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Principal Investigator: KHANDAN KEYOMARSI
Organization: UNIVERSITY OF TX MD ANDERSON CAN CTR
Fiscal Year: 2024
Award: $430,381
Funding agency: National Cancer Institute
As a recognized leader in cancer research,1 MD Anderson Cancer Center is uniquely positioned to train and support the career development of the next generation of cancer researchers. We will do so via early intervention programs that foster sustained interest in cancer research in students with limited research experience. Since 2011, we have directed a summer undergraduate training program encompassing 345 trainees (from 2011-2018). Significantly, outcomes for research limited trainees in our program are indistinguishable; research limited, and non-limited alumni are enrolled in or have completed STEM bachelor’s (98.8% vs 98.1%) and doctoral (both 67.1%) degrees and are retained in STEM education or workforce (98.3% vs 98.6%, respectively). Built upon these successes, we have designed a comprehensive cancer research training program for high school and undergraduates with limited exposure to cancer research via the R25 YES initiative. In our focused program, we address major barriers in the pursuit and success in STEM, including limited 1) research experience, 2) career path knowledge, and 3) scientific identity formation and exposure to science; 4) underdeveloped professionalism and communication skills; 5) inadequate research, educational, and career mentoring; and 6) barriers in the graduate application process. Our proposed UPWARDS Training Program (Undergraduate Students Working Towards Research in Science) has 3 tracks: full-time, 12-week summer research for 1) high-schoolers and 2) undergraduates and 3) part-time, 40-week research for undergraduates. Within each track, we propose the following aims to address the aforementioned barriers: Aim 1) Employ focused recruitment and holistic strategies for program involvement and deliver didactic learning and hands-on cancer research experiences through a cadre of outstanding mentoring faculty. Aim 2) Develop and deliver individualized mentoring, career exploration, and professional development that stimulates graduate education and cancer research career pursuit. Aim 3) Educate and inspire communities, young generations in the STEM pipeline, and the families and support systems of our students through training, STEM outreach, and hands-on engagement. We will encourage our trainees to lead and encourage their communities and younger generations through hands-on STEM outreach activities and design and delivery of community education. Aim 4) Implement and maintain a rigorous assessment program with continual appraisal and enactment of novel, evidence-driven best practices derived from these efforts. Lastly, we commit to disseminating our findings and best practices via peer-reviewed publications. Through the UPWARDS Program, we will build upon our prior experiences and best practices to launch a cancer research training program specifically designed to fit the needs of research limited trainees in our local community and nationally. We anticipate our efforts will effectively increase the STEM educational pipeline and cancer research workforce.
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