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Principal Investigator: Alexandrea L. Craft
Organization: WOMEN AND INFANTS HOSPITAL-RHODE ISLAND
Fiscal Year: 2024
Award: $437,475
Funding agency: NIH Office of the Director
PROJECT SUMMARY / ABSTRACT
Preterm infants are at a heightened risk for developing neuromotor, cognitive, and psychiatric disorders that
persist through adulthood. Infants born very preterm (<32 weeks gestational age) are three times more likely to
develop psychiatric disorders, including anxiety, ADHD, and autism compared to term infants. Critically, the
consequences of prematurity disproportionately impact Black and low SES families. The overall high
prevalence of prematurity, coupled with Black and low SES families’ increased risk, is a serious public
health concern. However, the mechanisms contributing to these disparities are largely unexplored. Identifying
modifiable mechanisms will help inform policies and practices that promote healthy neurodevelopment for
preterm infants and their caregivers. Parenting premature infants is challenging due to the physical parent-infant
separation in the neonatal intensive care unit (NICU). Extensive research has emphasized the important role of
parents and parental involvement in the NICU to promote infant neurodevelopment. Yet we know little about the
external contextual factors that impact and impede parent involvement, especially in diverse populations. A
significant barrier to NICU involvement may be conflicting work and family demands. >62% of families with
children include two working parents. Further, low-income families in particular return to paid work as soon as
four weeks after childbirth which can have implications for their ability to visit the NICU. Regrettably there is
virtually no research on NICU parents transition to parenthood from a work-family lens. The proposed
study will use a unique method, Ecological Momentary Assessment (EMA), to monitor parents’ daily mental
health, NICU involvement, and work/family demands during their infants’ NICU hospitalization in a racially and
ethnically diverse sample of 250 families (defined as a mother, a secondary caregiver, and their infant). We aim
to 1) examine stable and dynamic associations between work factors, NICU involvement, and caregiver
mental health utilizing a longitudinal EMA burst design; and 2) examine how work, NICU involvement,
and caregiver mental health are related to infant neurodevelopment. We hypothesize that caregivers with
ideal work policies and conditions (e.g., shorter work hours, more job flexibility, more job autonomy, more paid
leave) will have better mental health and more NICU involvement, which, in turn, will be associated with better
infant neurodevelopmental outcomes at NICU discharge and 1-year follow-up. Additionally, given the differential
NICU experience for Black and low SES families, we hypothesize that the associations between work, mental
health, NICU involvement, and infant neurodevelopment will be exacerbated for Black and low SES families.
Results from this study will address the important public health concern of prematurity in diverse families from a
unique work-family lens that may help identify family-level and state/federal policy-level intervention targets to
support parent NICU involvement and mitigate the long-term neurodevelopmental consequences of prematurity.
Terms: <0-11 years old><0-4 weeks old><21+ years old><AD/HD><ADHD><ASD><Achievement><Achievement Attainment><Active Follow-up><Address><Adult><Adult Human><Anxiety><Application Context><Area><Attention deficit hyperactivity disorder><Autism><Autistic Disorder><Back><Birth Rate><Black><Black race><Care Givers><Caregivers><Caring><Caucasian Females><Caucasian Women><Child><Child Rearing><Child Youth><Childbirth><Children (0-21)><Chronologic Fetal Maturity><Cognition Disorders><Color><Complex><Coupled><Development><Disparities><Disparity><Doctor's Degree><Doctorate Degree><Dorsum><Early Infantile Autism><Ecological momentary assessment><Family><Fetal Age><Funding><Gestational Age><Goals><Health><High Prevalence><Hispanic Females><Hispanic Women><Hospital Admission><Hospitalization><Hospitals><Hour><Individual><Infant><Infantile Autism><Institution><Intervention><Intervention Strategies><Jobs><Kanner's Syndrome><Knowledge><Leadership><Life><Manuscripts><Mental Health><Mental Hygiene><Mental disorders><Mental health disorders><Mentors><Methods><Mothers><Neonatal Intensive Care Units><Neural Development><Newborn Infant><Newborn Intensive Care Units><Newborns><Non-Hispanic><Nonhispanic><Not Hispanic or Latino><Occupations><Outcome><Paper><Parenting><Parenting behavior><Parents><Play><Policies><Population Heterogeneity><Postpartum Period><Predominantly Hyperactive-Impulsive Type Attention-Deficit Disorder><Predominantly Hyperactive-Impulsive Type Hyperactivity Disorder><Premature Birth><Premature Infant><Prematurely delivering><Preterm Birth><Professional Positions><Psychiatric Disease><Psychiatric Disorder><Psychological Health><Psychopathology><Public Health><Publications><Publishing><Research><Rhode Island><Risk><Role><Sampling><Schedule><Science><Scientific Publication><Secure><Social Justice><Techniques><Training><United States><Visit><White Females><White Women><Woman><Work><abnormal psychology><active followup><adulthood><autism spectral disorder><autism spectrum disorder><autistic spectrum disorder><black female><black women><black/white disparity><child birth><childrearing><cognitive disease><cognitive disorder><cognitive syndrome><contextual factors><design><designing><developmental><diverse populations><doctoral degree><ethnic diversity><ethnic minority><ethnically diverse><experience><extreme prematurity><extremely premature infant><extremely preterm><extremely preterm infant><federal policy><flexibility><flexible><follow up><follow-up><followed up><followup><heterogeneous population><infants born premature><infants born prematurely><interventional strategy><kids><lens><lenses><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><lower income families><mental illness><neonatal ICU><neurodevelopment><newborn child><newborn children><parent><parent monitoring><parent role><parental involvement><parental monitoring><parental role><population diversity><post-partum><posters><premature><premature baby><premature childbirth><premature delivery><premature infant human><prematurity><preterm baby><preterm delivery><preterm infant><preterm infant human><programs><psychiatric illness><psychological disorder><racial diversity><racial minority><racially diverse><skills><social role><statistics><undergrad><undergraduate><undergraduate student><very premature><very preterm><virtual><youngster>