Use of Bacteriophages to Prevent, Diagnose, and Treat Diseases

NIH Pandemic-Era Grants

Pandemic Era Grants

2024

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Principal Investigator: SANKAR  ADHYA
Organization: DIVISION OF BASIC SCIENCES - NCI
Fiscal Year: 2024
Award: $1,025,659
Funding agency: National Cancer Institute

Using our phage-based vaccine technology, we have succeeded (i) in eliciting highly specific vaccines against EGRvIII glioblastoma cancer cells in Mouse. This phage vaccine would next be tested by injecting into live model mouse. with EGFRvIII glioblastoma for efficacy. (ii) Constructed (in collaboration with Dr. Mitchell Ho) a Nanobody displaying phage that specifically neutralizes the activity of Covid19 pseaudovirus. This nanobody would next be tested for neutralization of live Covid 19 virus by injecting

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