Document text
Principal Investigator: SARAH E. DAUBER
Organization: PARTNERSHIP TO END ADDICTION
Fiscal Year: 2024
Award: $251,309
Funding agency: National Institute on Alcohol Abuse and Alcoholism
Abstract
The proposed R34 will develop and test digital helpline intervention components aimed at reducing heavy
episodic drinking (HED) during the first 3 months postpartum. HED is prevalent among women of reproductive
age, and more than half of women who reduce their drinking during pregnancy return to pre-pregnancy levels
within 3 months postpartum, making this a critical time for intervention. Addressing postpartum HED is key to
preventing negative maternal and child health outcomes, including fetal alcohol spectrum disorder in
subsequent pregnancies. Postpartum mothers are unlikely to seek treatment for HED, due to stigma and fear
of child removal. Helplines that use real-time synchronous text with a professional, as well as automated
messaging, are a promising mechanism for reaching postpartum mothers to deliver effective brief interventions
for HED, as they are widely accessible, convenient, free, and anonymous. The proposed study will apply the
Multiphase Optimization Strategy (MOST) framework to develop standard helpline interventions (assessment,
psychoeducation, and links to resources), and evidence-based brief interventions for alcohol use (motivational
interviewing and coping skills training), all tailored to the postpartum period and delivered via scheduled
sessions of synchronous texting with a helpline specialist. The standard helpline component will also include
the asynchronous support typical of helplines. Following development, a pilot factorial trial will evaluate the
standard helpline interventions for this unique population, examine the feasibility and added value of evidence-
based brief interventions delivered via helpline, and assess the added impact of 4 weeks of automated
messages to provide ongoing reinforcement of intervention content. Specific aims are to (1) develop
intervention components, Helpline staff training, and fidelity monitoring protocols via an iterative user-centered
design process with 15 mothers, 5 helpline specialists, and an expert panel; and (2) conduct a pilot 2X2X2
factorial trial with 120 new mothers to assess feasibility, acceptability, and fidelity of each intervention
component, and obtain preliminary proof-of-concept effects of intervention components on proximal
(motivation, self-efficacy, and self-regulation) and distal (quantity and frequency of HED) outcomes to prepare
for a future fully-powered optimization trial. Study products will be a set of piloted intervention components for
delivery via digital helpline, ready for optimization and evaluation in an R01. Partnership to End Addiction’s
existing Helpline infrastructure will support future testing and ultimate scalability.
Terms: <0-11 years old><Abscission><Address><Age><Alcohol Drinking><Alcohol consumption><Characteristics><ChatGPT><Child><Child Abuse and Neglect><Child Health><Child Youth><Childhood maltreatment><Children (0-21)><Client><Coping Skills><Data><Development><Distal><EtOH drinking><EtOH use><Evaluation><Excision><Extirpation><FASD><Family><Family member><Fear><Feedback><Fetal Alcohol Spectrum Disorder><Focus Groups><Frequencies><Fright><Future><GPT-2><GPT-3><GPT-4><Gestation><Goals><Individual><Infant Care><Informal Social Control><Infrastructure><Intervention><Intervention Strategies><Interview><Investments><Link><Maternal and Child Health><Methods><Monitor><Mothers><Motivation><Outcome><Participant><Phone><Population><Postpartum Period><Pregnancy><Process><Protocol><Protocols documentation><Psychological reinforcement><Public Health><Randomized><Reinforcement><Removal><Research><Research Resources><Resources><Risk><Sampling><Schedule><Self Efficacy><Self Regulation><Services><Specialist><Surgical Removal><System><Techniques><Telephone><Testing><Text><Text Messaging><Time><Training><Woman><Women's prevalence><addiction><addictive disorder><ages><alcohol ingestion><alcohol intake><alcohol product use><alcohol use><alcoholic beverage consumption><alcoholic drink intake><automated text message><automated texting><baby care><barriers to implementation><behavior change><binge alcohol consumption><binge drinking><brief alcohol intervention><brief intervention><brief therapy><brief treatment><cease smoking><child maltreatment><child protection services><child protective service><coping strategy><cost effective><design><designing><develop therapy><developmental><digital><drinking><effective therapy><effective treatment><episodic drinking><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><evidence base><facilitators to implementation><family support><female prevalence><high risk><implementation barriers><implementation challenges><implementation facilitators><infant health care><infant healthcare><innovate><innovation><innovative><intervention delivery><intervention development><intervention effect><interventional strategy><kids><motivational enhancement therapy><motivational interview><multiphase optimization strategy><newborn care><perinatal mental health><post-partum><post-partum care><postpartum care><prepregnancy><prevalence among females><prevalence among women><prevalence in females><prevalence in women><prevalent among females><prevalent among women><prevalent in females><prevalent in women><prevent><preventing><psychoeducation><quit smoking><randomisation><randomization><randomly assigned><reproductive><resection><satisfaction><short message service><skills training><smoking cessation><social stigma><stigma><stop smoking><substance use><substance using><synchronous contact><synchronous encounter><synchronous session><text based intervention><text intervention><text messaging based intervention><text messaging intervention><texting><therapy development><treatment development><uptake><user centered design><youngster>