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Principal Investigator: Daniel Hal Solomon
Organization: BRIGHAM AND WOMEN'S HOSPITAL
Fiscal Year: 2024
Award: $891,115
Funding agency: National Institute of Arthritis and Musculoskeletal and Skin Diseases
PROJECT SUMMARY
The overarching long-term aims of VERITY are: 1) to develop state-of-the-art methods for clinical research in
rheumatology and musculoskeletal diseases that are relevant for the Research Community, 2) to deliver
methodologic and bioinformatic assistance to the Research Community, and 3) to train the Research
Community in state-of-the-art methods through courses, seminars, and mentoring. During the last cycle,
VERITY recruited a large and growing Research Community of rheumatic and MSK disease investigators who
participate in courses, mentoring, and utilize the services of the three VERITY Cores. The Overall Section of
the application describes: the progress and future directions for VERITY’s burgeoning Research Community;
how VERITY has developed and delivered courses to respond to the Research Community’s needs, especially
during the COVID pandemic; plans for future courses and mentoring of trainees and junior faculty; and the
services offered and organization of the Methodology Core and the Bioinformatics Core. During the previous
cycle, VERITY developed a diverse Research Community that has included many junior faculty and trainees, a
good number of pediatric rheumatologists, and an increasing group of MSK investigators. These researchers
represent the tremendous diversity of clinical investigators engaged with NIAMS-focused topics. In addition,
the large group of investigators helps provide the Cores with a steady stream of activity and resources.
During the prior cycle of the BWH CCCR, VERITY helped produce 160 original articles already cited 1,287
times. These original articles appeared in high impact journals. The VERITY Research Community has
been successful with 109 grant submissions during the last 4+ years, tabulating a total of $40,073,225
in annual direct research revenues. The three Cores have been extremely productive and learned much
about working effectively with the Research Community. The proposed aims build on the prior successes with:
an enhanced Enrichment Program increasing the focus on URiM researchers in rheumatology; a Methodology
Core that ensures methodologic rigor while incorporating behavioral theory and economics into studies
focused on racial and ethnic minorities; and a Bioinformatics Core that provides bioinformatic support to better
phenotype patient cohorts, allowing for studies of social determinants of health.
Terms: <21+ years old><Adult><Adult Human><Behavioral><Bio-Informatics><Bioinformatics><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Case Study><Childhood><Clinical><Clinical Investigator><Clinical Research><Clinical Study><Communities><Conduct Clinical Trials><Data><Economics><Ensure><Faculty><Future><Grant><Hospitals><Intervention><Intervention Strategies><Investigators><Journals><Learning><Machine Learning><Magazine><Mentors><Mentorship><Methodology><Methods><Minority researcher><Musculoskeletal><Musculoskeletal Diseases><Musculoskeletal Pain Disorder><NIAMS><National Institute of Arthritis, and Musculoskeletal, and Skin Diseases><Paper><Patients><Perception><Persons><Phenotype><Productivity><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research Support><Research Training><Researchers><Resources><Rheumatic Diseases><Rheumatism><Rheumatologic Diseases><Rheumatologic Disorder><Rheumatology><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Scientific Publication><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Stream><Training><Underrepresented Ethnic Minority><Underrepresented Minority><Woman><Work><adulthood><advanced analytics><behavioral economics><bio-informatics resource><bioinformatics resource><case report><cohort><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><data integration><design><designing><economic><ethnic minority><improved outcome><interventional strategy><machine based learning><minority investigator><musculoskeletal disorder><next generation><pediatric><phenotypic data><programs><racial minority><recruit><research study><rheumatologist><service utilization><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><skills><social health determinants><success><theories><tool><treatment effect><under-representation of minorities><under-represented minority><underrepresentation of minorities>