Document text
Principal Investigator: ARLEEN F. BROWN
Organization: UNIVERSITY OF CALIFORNIA LOS ANGELES
Fiscal Year: 2024
Award: $9,718,232
Funding agency: National Center for Advancing Translational Sciences
SUMMARY/ABSTRACT
The UCLA Clinical and Translational Science Institute is a research partnership of the University of California
Los Angeles, Cedars-Sinai Medical Center, Charles R. Drew University of Medicine and Science and the Harbor-
UCLA Medical Center/ Lundquist Institute for Biomedical Innovation. Our mission is to bring biomedical
innovations to bear on the greatest health needs of Los Angeles, an ethnically and economically diverse
metropolis of more than 10 million people. In the past 10 years, we have built a robust research infrastructure to
support our mission. In partnership with the community, we have made important advances against the leading
causes of preventable disability and death. Supporting these advances is a streamlined regulatory infrastructure.
We have instituted scientific review, reduced time-to-study-activation by 42%, and achieved 100% compliance
with ClinicalTrials.Gov. As we enter our next decade, we are building on our progress by augmenting the
integration with our institutional hub partners and broadening collaborations in the community as well as with
investigators outside the health professions. Because Equity, Diversity and Inclusion (EDI) is a foundational
principle of our CTSI, we have embarked on an Inclusive Science Initiative, led by our EDI Senior Associate
Director, to ensure that our research and training programs continue to embrace this guiding principle. Through
new T1-T4 seminars and team science trainings and opportunities, we are equipping our trainees to conduct
multidisciplinary team science across the translational spectrum. We are systematically evaluating our CTSI
outcomes and overall impact. The UCLA CTSI has five specific aims: 1) Enhance education and training to
prepare and expand the translational workforce, 2) Engage stakeholder communities in multidisciplinary
team science and disseminate successful models of collaboration, 3) Integrate special populations,
including those experiencing health disparities, into translational research, 4) Improve methods and
processes to accelerate efficient, high-quality, multisite research, and 5) Provide informatics solutions
to advance high-impact translational science.
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