Non-Human Primate Lymphoid Organ Chips for Vaccine Assessment
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Organization: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES Fiscal Year: 2024 Award: $1,000,000 Funding agency: National Institute of Allergy and Infectious Diseases To support the development of a non-human primate (NHP) lymph node (LN) microphysiologic system/tissue-on-a-chip with a focus on modeling immune responses to anti-viral vaccines (influenza, SARS-CoV-2) and testing the efficacy of these medical countermeasures. Terms: <2019 novel corona virus><2019 novel coronavirus><2019-nCoV><2019-nCoV vaccine><Body Tissues><COVID-19 vaccine><COVID-19 virus><COVID19 virus><CoV-2><CoV2><Development><Grippe><Immune response><Immunologic Model><Immunological Models><Immunological response><Influenza><Lymph Node Reticuloendothelial System><Lymph node proper><Lymphatic nodes><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 vaccine><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 vaccine><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 vaccine><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 vaccine><Severe acute respiratory syndrome related corona virus 2><Tissues><Vaccines><Viral Vaccines><Wuhan coronavirus><coronavirus disease 2019 vaccine><coronavirus disease 2019 virus><coronavirus disease-19 vaccine><coronavirus disease-19 virus><develop a vaccine><develop vaccines><development of a vaccine><developmental><efficacy testing><hCoV19><host response><immune system response><immunoresponse><lymph gland><lymph nodes><lymph organ><lymphatic organ><lymphnodes><lymphoid organ><medical countermeasure><microphysiologic model><microphysiologic platform><microphysiologic system><microphysiology model><microphysiology platform><microphysiology system><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><nCoV2><non-human primate><nonhuman primate><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine candidates against SARS-CoV-2><vaccine development><vaccine for novel coronavirus><vaccines preventing COVID><vaccines to prevent COVID>