Document text
Principal Investigator: Rebeca Wong
Organization: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
Fiscal Year: 2024
Award: $1,694,384
Funding agency: National Institute on Aging
The Mexican Health and Aging Study (MHAS) is a longitudinal study using a national sample of community-dwelling
adults aged 50 and older in urban and rural Mexico. Six waves of data collection over 20 years have
been completed. Since its inception, the protocols and survey instruments are highly comparable to the U.S.
Health and Retirement Study (HRS), A key ancillary study of the MHAS is the Mex-Cog, part of the
Harmonized Cognitive Aging Protocol (HCAP), conducted in several countries to study Alzheimer's disease
and related dementias (ADRD) around the globe using population-based surveys like the MHAS. Two waves of
the Mex-Cog have been completed.
The long-term goal is to create new knowledge on aging and ADRD for Mexican older adults using a
population-based life course perspective. The MHAS is uniquely positioned to sustain research on emerging
themes such as COVID-19 and the related social inequities it revealed, providing a strong rationale for adding
follow-ups of the MHAS and Mex-Cog, and incorporating new themes to address these knowledge gaps, The
specific aims are to: 1) Support further research on the dynamics of aging in Mexico, by extending and
improving an existing national panel study, the MHAS. 2) Support further research on the dynamics of
Alzheimer's disease and related dementias around the globe, by extending an existing panel of Mex-Cog, an
ancillary study of the MHAS; and 3) Foster research on the dynamics of Mexican aging by expanding the
knowledge about and promoting the use of the databases and its related products. We will carry out waves 7
and 8 of the MHAS and Wave 3 of the Mex-Cog, We will add a rural over-sample, and incorporate new
themes: COVID-19, discrimination, use of languages, and use of technology for health care. We will collect
saliva samples in Mex-Cog 3 to support research on genetics of Alzheimer's disease. We will continue the
user-friendly web-based platforms and launch a new virtual data enclave to enhance global public access to
the data and project documentation.
The analytical significance of the new MHAS data will be exceptional, producing a national longitudinal study of
aging that spans over twenty-six years, which is unique for a low or middle-income country, The data platform
will enhance research on aging in general and ADRD more specifically, and related changes of physical and
mental health; physical and cognitive functionality; COVID-19 and other environmental risks; health behaviors
and health care use; family support; aging and the life course; wealth, income, labor and retirement; Mexico-U.S. migration; and mortality in a country aging fast with limited institutional support for individuals in old age,
and with close social and economic ties to the United States. The data will enable cross-period and cross-cohort
analyses, as well as short- and long-run effects on health and aging, and will continue to be highly
comparable with similar studies in other countries.
Terms: <21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><AD dementia><AD related dementia><ADRD><Active Follow-up><Address><Adult><Adult Human><Aged 65 and Over><Aging><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease related dementia><Alzheimers Dementia><Ancillary Study><Blood><Blood Reticuloendothelial System><COVID crisis><COVID epidemic><COVID pandemic><COVID-19><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 pandemic affected><COVID-19 pandemic consequence><COVID-19 pandemic effects><COVID-19 pandemic impact><COVID-19 pandemic impacted><COVID-19 period><COVID-19 public health crisis><COVID-19 years><CV-19><Cognitive><Cognitive Discrimination><Cognitive aging><Cohort Analyses><Cohort Analysis><Collaborations><Communities><Coronavirus Infectious Disease 2019><Country><DNA Methylation><Data><Data Bases><Data Collection><Databases><Developing Countries><Developing Nations><Dimensions><Discrimination><Documentation><Economic Income><Economical Income><Economics><Elderly><Environmental Factor><Environmental Risk Factor><Epigenetic><Epigenetic Change><Epigenetic Mechanism><Epigenetic Process><Equity><Family><Fostering><Funding><Genetic><Geography><Geriatrics><Goals><Health><Health Care Technology><Health Technology><Health and Retirement Study><Health behavior><Healthcare><Healthcare Technology><Income><Individual><Inequity><Institution><Interdisciplinary Research><Interdisciplinary Study><Investigators><Knowledge><Language><Latin America><Lead><Length><Less-Developed Countries><Less-Developed Nations><Life Cycle><Life Cycle Stages><Link><Longitudinal Studies><Mental Health><Mental Hygiene><Mexican><Mexico><Multidisciplinary Collaboration><Multidisciplinary Research><NIH><National Institutes of Health><Participant><Pb element><Peer Review><Physical Function><Population><Position><Positioning Attribute><Primary Senile Degenerative Dementia><Protocol><Protocols documentation><Psychological Health><Research><Research Personnel><Research Support><Researchers><Retirement><Running><Rural><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Saliva><Sampling><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social Protection><Spanish/English><Structure><Survey Instrument><Surveys><Third-World Countries><Third-World Nations><Under-Developed Countries><Under-Developed Nations><United States><United States National Institutes of Health><Venous><Work><above age 65><access to health care><access to healthcare><accessibility of health care><accessibility to health care><accessibility to healthcare><active followup><adulthood><advanced age><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged><aged 65 and greater><aged 65+><aged ≥65><bilingual><bilingualism><cognitive function><coronavirus disease 2019><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 pandemic consequence><coronavirus disease 2019 pandemic impact><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><coronavirus infectious disease-19><data base><data driven platform><data enclave><data platform><design><designing><developing country><developing nation><economic><effects following the COVID-19 pandemic><empowerment><environmental risk><epigenetically><experience><experienced discrimination><family support><follow up><follow-up><followed up><followup><geriatric><geriatric medicine><health care><health care access><health care availability><health care service access><health care service availability><health related behavior><healthcare access><healthcare accessibility><healthcare availability><healthcare service access><healthcare service availability><heavy metal Pb><heavy metal lead><human old age (65+)><impact of the SARS-CoV-2 pandemic><improved><incomes><instrument><internet based platform><internet platform><life course><long-term study><longitudinal outcome studies><longterm study><migration><mobile computing><mobile platform><mobile technology><mortality><old age><older adult><older adulthood><outreach><over 65 years><perceived discrimination><perception of discrimination><physical conditioning><physical health><population based><preservation><primary degenerative dementia><programs><response><retirements><rural area><rural location><rural region><saliva sample><salivary sample><self-reported discrimination><senile dementia of the Alzheimer type><senior citizen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social><statistics><trend><usability><user-friendly><virtual><web based platform><web based system><web enabled platform><web platform><web site><website><≥65 years>