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9873 documents

Function Assessment Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Roger A. Fielding · BRIGHAM AND WOMEN'S HOSPITAL · 2024 · $438,138 — SUMMARY / ABSTRACT Preserving late-life mobility, defined as the ability to walk safely and independently, is central to maintaining a high quality of life, is critical for the performance of many activities of daily living and is necessary for maintaining physical independence. Therefore, the conti…

Development Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Susan W Parker · UNIV OF MARYLAND, COLLEGE PARK · 2024 · $149,676 — PROJECT SUMMARY The Development Core has, as its primary mission, the development, support, and promotion of population research of the highest scientific merit, in line with our four Primary Research Areas: Gender, Family and Social Change, Health in Social Context, Social and Economic Inequality, …

Exploratory-Project 2

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Maria A Oquendo · UNIVERSITY OF PENNSYLVANIA · 2024 · $295,155 — PROJECT SUMMARY Suicide is inherently an affectively charged topic and clinicians often experience anxiety and low self-efficacy in detecting and intervening with those at risk. This anxiety leads to poor implementation of evidence-based suicide screening, assessment, and interventions (SSAIs). Cl…

A Cardiometabolic Health Program LINKED with Clinical-Community Support and Mobile HEAlth TelemonitoRing in Underserved PopulaTionS (LINKED-HEARTS PROGRAM)

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Yvonne Commodore-Mensah · JOHNS HOPKINS UNIVERSITY · 2024 · $658,161 — Project Summary/Abstract Innovation in chronic disease management is urgently needed to effectively control hypertension (HTN) and diabetes, conditions which affect millions of Americans. Uncontrolled HTN and diabetes cause cardiovascular disease, stroke, chronic kidney disease (CKD), and premature …

Lynch Vaccine

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Steven M Lipkin · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $345,292 — Project 1: Project Summary/Abstract Lynch syndrome (LS) affects ~1.2 million Americans and predisposes them to colorectal cancer (CRC) and other malignancies. LS normal cells acquire somatic second mutations and become DNA mismatch repair deficient (MMRD). MMRD tumors have exceptionally high numb…

Facility Management, Maintenance and Operations Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

George Parsons Langan · UNIVERSITY OF CHICAGO · 2024 · $1,081,907 — PROJECT ABSTRACT (Core 1/C1Facilities@HTRL) Core 1 Facility Management, Maintenance and Operations Core (C1Facilities@HTRL) The Facility Management, Maintenance, and Operations Core will operate the Howard T Ricketts Regional Biocontainment Laboratory (HTRL) A/BSL3 to ensure continuous containment t…

BSL3 Practices Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

JAY RAPPAPORT · TULANE UNIVERSITY OF LOUISIANA · 2024 · $1,376,860 — The Biosafety Level 3 (BSL-3) Practices Core (Core 2) will support the research goals of the Regional Biocontainment Laboratory (RBL) at the Tulane National Primate Research Center (TNPRC) by continuing to ensure a safe and secure environment for work with high-consequence pathogens. To do so requir…

Data Management and Distribution Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

COULSON KGATHI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · 2024 · $49,352 — Project Summary/Abstract, Data Management and Distribution Core (Core B) The proposed program project aims to close research gaps in antiretroviral treatment for pregnant women and infants living with HIV with four inter-related projects that will require data management and data sharing. The Data M…

RC1 - The Data and Analysis Core (DAC)

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

W. JOHN BOSCARDIN · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $344,226 — PROJECT SUMMARY ABSTRACT – Data and Analysis Core (DAC) Research on function and disability in vulnerable older adults involves methodological and analytical challenges. Addressing these challenges often requires specialized expertise and approaches, including methods for working with data ranging f…

Administrative Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Vivian Colon · UNIVERSITY OF PUERTO RICO MED SCIENCES · 2024 · $683,127 — PROJECT SUMMARY/ABSTRACT: ADMINISTRATIVE CORE The CePCHE Administrative Core (AC) will consist of 5 components: (1) administration and finances, (2) monitoring and evaluation, (3) External Advisory Committee (EAC), (4) Internal Advisory Committee (IAC), and (5) training and Outreach/In-Reach. The AC…

Administrative Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Jaime L Matta · PONCE SCHOOL OF MEDICINE · 2024 · $200,815 — ABSTRACT | ADMINISTRATIVE CORE The Administrative Core (AC) of the Ponce Health Sciences University-Moffitt Cancer Center (PHSU-MCC) Partnership serves as its central coordinating component. The AC manages all aspects of the Partnership including day-to-day administrative and financial supervision, …

CEIRR: SARS-CoV-2 Research Activities

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

RICHARD WEBBY · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · 2024 · $602,070 — CEIRR will determine the molecular, ecologic and/or environmental factors that influence the evolution, emergence, transmission and pathogenicity of respiratory viruses, including coronaviruses such as SARS-CoV-2, and characterize the immune response to infection to improve understanding of the immu…

Project 1: Characterization of the Antibody Response to SARS-CoV-2 in Lung Cancer Patients

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Florian Krammer · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $119,920 — PROJECT 1: ABSTRACT Current information indicates that, in persons without cancer, natural infection with SARS-CoV-2 as well as vaccination with COVID-19 vaccine candidates induce antibody responses to the spike protein of the virus which should be protective against future infection. Lung cancer pa…

Project-004

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

MADHAV V DHODAPKAR · EMORY UNIVERSITY · 2024 · $88,878 — Abstract: The Emory U54 SeroNET U54 program is a multidisciplinary program that brings together experienced team of investigators to tackle fundamental issues relating to immunity to SARS CoV-2, particular in patients with cancer and autoimmunity. The team has a long track record of prior work in ba…

Immune Mechanisms of Protection Against Mycobacterium Tuberculosis Center (IMPAC-TB)

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

KEVIN URDAHL · SEATTLE CHILDREN'S HOSPITAL · 2024 · $5,443,065 — The goal of this program is to establish an integrated multi-disciplinary team of highly collaborative investigators that will plan and conduct iterative, in-depth immunologic analyses of tissue-specific and systemic responses in small animals, non-human primates (NHPs), and humans to identify the k…

Research Education Core

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Liya Escalera · UNIVERSITY OF MASSACHUSETTS BOSTON · 2024 · $369,198 — PROJECT SUMMARY The UMass Boston Dana-Farber/Harvard Cancer Center Partnership’s Research Education Core (REC) aims to bridge the divide that exists in the biomedical workforce by increasing the number of UMass Boston students, particularly those from underrepresented populations, to pursue graduat…

Discovery of Adjuvants for mRNA Vaccines

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

DENNIS CARSON · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2024 · $2,601,750 — The offeror’s proposed work plan aims to identify, characterize and optimize non-toxic, low molecular weight agents as adjuvants that a) enhance protein antigen accumulation and release in non-immune and immune cells after intramuscular administration of mRNA vaccine and b) stimulate innate immune…