Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Anna D. Johnson · GEORGETOWN UNIVERSITY · 2024 · $643,467 — Project Summary The COVID-19 pandemic poses a sustained threat to the wellbeing of all children, but particularly for low- income, racially minoritized, and special needs subgroups. This unpredictable, complex, racialized crisis has exposed millions of children to massive disruptions of their educat…
CINDY H LIU · BRIGHAM AND WOMEN'S HOSPITAL · 2024 · $859,895 — PROJECT SUMMARY/ABSTRACT The United States does not have sufficient science to mount an evidence-based response to combat the health detriments of present-day anti-Asian American (AA) hate. AA parents and children are struggling with a deeply troubling new sociopolitical context, a context with unpr…
Carla Boutin-Foster · SUNY DOWNSTATE MEDICAL CENTER · 2024 · $522,020 — Project Abstract The Downstate Clinical Research Scholars Training Program (CREST) will provide a structured program that prepares nurses and physicians to conduct rigorous research that addresses health disparities and advances health equity. The COVID-19 pandemic coupled with acts of social injust…
KAMAKSHI LAKSHMINARAYAN · UNIVERSITY OF MINNESOTA · 2024 · $413,463 — Project Summary The Upper Midwest Regional Coordinating Center (RCC), previously the University of Minnesota (UMN) RCC, is an established, high-performance RCC within Stroke Net. The pillars of the Upper Midwest Stroke Net RCC are: 1) unparalleled expertise in clinical trial conduct with a track rec…
David Michael Markovitz · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $714,193 — The huge loss of life and major damage to the social fabric that is caused by a viral pandemic has been brought graphically to light with the current SARS-CoV-2 (COVID-19) crisis. Clearly, broad-spectrum antiviral agents that are effective therapeutically and prophylactically against SARS-CoV-2, ant…
Sonya Reid · RHODE ISLAND HOSPITAL · 2024 · $732,687 — Project Summary People with cancer have a higher risk of infections in general because of vulnerabilities arising from their cancer and its treatments. This is especially true for the novel coronavirus, SARS-CoV- 2. People with cancer are twice as likely to die from COVID-19 compared to the general …
Nicholas S Heaton · DUKE UNIVERSITY · 2024 · $713,913 — PROJECT SUMMARY/ABSTRACT Influenza viruses induce significant morbidity and mortality in the human population every year. Despite the medical importance of influenza disease, the mechanisms underlying the viral pathogenesis are incompletely understood. After influenza viruses initiate infection, cel…
Aida Sivro · CENTRE/AIDS PROGRAMME/RES/SOUTH AFRICA · 2024 · $122,682 — ABSTRACT Previously, we carried out large-scale analysis of mucosal cytokines and HIV acquisition in high-risk women from KwaZulu-Natal, South Africa, enrolled as part of the CAPRISA 004 TFV 1% gel study (n = 774). Using a prospective cohort design, we validated our previous finding that inflammator…
TREVOR P. CASTOR · APHIOS CORPORATION · 2024 · $300,000 — PROJECT SUMMARY COVID-19, the multiorgan disease caused by the novel coronavirus SARS-CoV-2, has become the most impactful healthcare, social, and economic crisis of our lifetime. SARS-CoV-2 is genetically related to the previous two coronaviruses that caused human outbreaks in the 21st century, SAR…
Moriel Zelikowsky · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2024 · $571,982 — PROJECT SUMMARY/ ABSTRACT Extended deprivation of social contact can produce deleterious effects on the brain and behavior. Social isolation (SI), or its perception (loneliness), is as predictive a risk factor for poor health outcomes as smoking or obesity. Many factors have contributed to a modern …
Jonathan L Zelner · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $645,067 — Modified Project Summary/Abstract Section ABSTRACT The distribution of disease and death from the COVID-19 pandemic was characterized by wide geographic and sociodemographic variation. Lower-risk, wealthier, and Whiter individuals have received earlier access to vaccination than their counterparts…
KANWALJEET S ANAND · STANFORD UNIVERSITY · 2024 · $1,003,564 — Adverse childhood experiences (ACEs), parenting, and social determinants of health (SDH) contribute to early life adversity (ELA), which can disrupt development in the brain, cardiovascular, metabolic, and immune systems to increase the risks for chronic non-communicable diseases, substance abuse, o…
CATHERINE M KOTZ · MINNEAPOLIS VA MEDICAL CENTER · 2024 — Aging and the chronic diseases associated with aging, such as obesity and neurodegeneration, combined with military service (trauma, burn pit exposure etc.) make old age Veterans more vulnerable to community-acquired viral pathogens. This reduces quality of life for Veterans and places a tremendous …
WENDY M. CAMPANA · VA SAN DIEGO HEALTHCARE SYSTEM · 2024 — It is increasingly apparent that Schwann cells (SCs) in the peripheral nervous system (PNS) function as a unit with neurons to regulate sensory function. When the PNS is injured or stressed, SCs become activated for repair. This involves dramatic SC phenotypic transformation. If this process is abno…
Bryan R Greenhouse · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $197,226 — Abstract Dr. Greenhouse is a physician scientist trained in internal medicine, infectious diseases, and biostatistics. Over the past 18 years, he has worked across domains of field epidemiology, laboratory science, data science, and public health to investigate the epidemiology of infectious diseas…
Jennifer M. Puck · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $20,000 — Project Summary Primary immune deficiencies (PIDs) are a group of over 480 rare disorders of the immune system that result in increased susceptibility to infections, autoimmunity, and malignancies. The most severe forms of PIDs are fatal unless immune reconstitution is achieved by hematopoietic cel…
Andrea L Kasinski · PURDUE UNIVERSITY · 2024 · $386,127 — PROJECT SUMMARY Like the challenges and skepticism that faced the antibody therapeutics field over a decade ago, RNA therapeutics is facing the same. And, like the antibody therapeutics field, we are beginning to realize the clinical impact of RNA therapeutics amiss these challenges. This is most cl…
MANUEL R AMIEVA · STANFORD UNIVERSITY · 2024 · $1,484,612 — Stanford/UNC Biomimetic U19 Research Center PROJECT SUMMARY/ABSTRACT – CENTER OVERVIEW Infectious diseases continue to pervasively afflict global health and socioeconomic stability despite substantial prevention and treatment initiatives. Respiratory and gastrointestinal pathogens rank amongst the m…
Susan Cheng · CEDARS-SINAI MEDICAL CENTER · 2024 · $718,171 — Project Summary In the midst of emerging threats from sporadic viral entities, the perennial influenza viral strains continue to impose a substantial burden of morbidity and mortality that compounds total annual risks to the population at large. Last season (2018-19), influenza affected 35.5 million…
Maria Marquine · DUKE UNIVERSITY · 2024 · $185,236 — PROJECT SUMMARY The proposed K24 Midcareer Investigator Award in Patient-Oriented Research aims to best enable the Principal Investigator, Dr. María Marquine, to advance research on neurocognitive disparities in aging and Alzheimer’s Disease and Related Dementias (ADRDs) among Hispanics/Latinos/as/x…