NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Stephanie Lina Gaw · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $686,531 — ABSTRACT Passive transfer of immunoglobulins (IgG) against SARS-CoV-2 occurs from the mother to fetus by transplacental transfer and may protect the neonate against infection or cause disease. Recent studies have shown maternal SARS-CoV-2 infection leads to the dysregulation of infant immune respons…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Jeremy Dahl · SONOVANCE, INC. · 2024 · $294,641 — Abstract As currently practiced, ultrasound imaging, recognized universally as being of great health care importance, requires the operator to have considerable training and anatomic and medical image understanding. Access to low-cost imaging services for millions of patients in-home, rural areas an…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
LORRAINE E LEVITT KATZ · CHILDREN'S HOSP OF PHILADELPHIA · 2024 · $865,708 — ABSTRACT While obesity, ancestry, family history of diabetes, insulin resistance, and puberty are all risk factors for pediatric-onset type 2 diabetes (T2D), identifying the subset of youth at greatest risk of advancing from “prediabetes” to T2D and the mechanisms underlying the deterioration remain…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Huilin Li · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $381,375 — With the steady growth of longitudinal microbiome studies, microbiomes are now on the cusp of clinical utility for several diseases, including obesity, diabetes, inflammatory bowel disease, and cancer. Motivated by the PI’s broad microbiome collaborations at New York University Langone Health and bu…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
John Richard Pamplin · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $177,962 — PROJECT SUMMARY Deaths due to opioid overdose are a pressing public health crisis and the number of deaths per year is increasing. Rates of fatal overdose are rising faster for Black people than for any other racial/ethnic group, largely driven by the increased prominence of synthetic opioids. Black…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Hilliard Kutscher · POP BIOTECHNOLOGIES, INC · 2024 · $950,225 — Abstract Influenza is the cause of considerable morbidity and mortality globally. Despite immunization being the most effective and economical prophylactic approach, vaccines often provide less than optimal defense against an influenza virus infection and illness. While hemagglutinin (HA) is the pri…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
KATHLEEN C INSEL · UNIVERSITY OF ARIZONA · 2024 · $844,799 — Abstract Mild cognitive impairment (MCI) is characterized by mild impairment in one or more cognitive functions and is associated with an increased risk for failure to take prescribed medications. Hypertension is prevalent among persons with MCI (PwMCI) and nonadherence to medications increases the …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Emma May Gorin · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $36,053 — ABSTRACT Policy makers, researchers and public health officials rely on forecasts from infectious disease models to anticipate resource use, assess risk, and plan public health interventions. In order to effectively and accurately predict future cases and hospitalization rates of COVID-19, these mod…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Araba Nayena Blankson · SPELMAN COLLEGE · 2024 · $311,324 — PROJECT SUMMARY The research focuses on examining African American children across a broad range of socioeconomic statuses (SES), avoiding the inherent confound in examination of only low-income African American children. In the proposed research, cognitive processes (fluid reasoning, executive func…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
E GLORIA CLAUDETTE REGISFORD · PRAIRIE VIEW AGRI & MECH UNIVERSITY · 2024 · $437,258 — URISE at PVAMU PI/PD: Regisford The increasing need for a well-trained STEM workforce, made more poignant during this COVID-19 pandemic, also requires a diverse population to meet the future needs and challenges in the biomedical sciences. An Undergraduate Research Training Initiative for Student E…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Jamie Estock · VETERANS HEALTH ADMINISTRATION · 2024 — Background: Prior to the pandemic, the approximately 10,000 Veterans on insulin pumps (VIPs) were excluded from VA telehealth programs due to the complexity of their care and their risk of adverse events (AEs). The lack of enrollment of VIPs in VA telehealth programs resulted in a gap in knowledge o…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Colleen Renee Kelly · AMERICAN GASTROENTEROLOGICAL ASSN/INST · 2024 · $673,041 — PROJECT SUMMARY Fecal microbiota transplantation (FMT) is an established treatment for patients with recurrent Clostridioides difficile infection (CDI). Although most patients with CDI can be successfully treated, the subset of acutely ill patients with severe and fulminant CDI is a much greater ch…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Changchun Liu · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · 2024 · $505,996 — Abstract Cervical cancer is among the leading causes of cancer death in women worldwide, especially in low- and middle- income countries (LMICs). High-risk human papillomaviruses (HPV) are the main causative agents of cervical cancer and its precursor lesions; therefore, the World Health Organizatio…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Kris Hauser · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · 2024 · $387,363 — This project proposes to enable a complete system for robotic optometric I ophthalmic examination of freestanding patients, including automated cornea , lens, and retinal imaging as well as eyeglass prescription measurement. Robot-aided medical exams have the potential to improve access to preven…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Ivona Vasile Pandrea · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $793,137 — Antiretroviral therapy (ART) has dramatically changed the landscape of chronic HIV infection and massively reduced mortality in persons living with HIV (PWH). Yet, many PWH present with intestinal dysfunction, residual immune activation and inflammation, incomplete immune restoration and a hypercoag…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
James G. Kublin · FRED HUTCHINSON CANCER CENTER · 2024 · $74,999 — PROJECT SUMMARY ANNUAL TRANSLATIONAL HIV EARLY STAGE INVESTIGATOR (ESI) CONFERENCE This R13 application requests continued NIH support for four annual conferences for Early Stage Investigators (ESIs) conducting translational HIV vaccine, cure, immunology, and co-infection research with non-human pri…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Laurent Olivier Mosnier · SCRIPPS RESEARCH INSTITUTE, THE · 2024 · $452,500 — Project Summary This application seeks to improve basic understanding of the molecular mechanisms that mediate cytoprotective actions of coagulation proteases on cells and will test novel approaches for the potential treatment of thrombo- inflammatory disease. Despite recent advances, major gaps in …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
George B Sigal · MESO SCALE DIAGNOSTICS, LLC · 2024 · $837,128 — Our objective is to develop better assays for measuring antibodies produced in people after influenza infection or vaccination. We’ll develop assays that measure total antibody responses, and assays that specifically measure the antibodies responsible for protection from infection. By using high-thr…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
PEARL H CHIU · VIRGINIA POLYTECHNIC INST AND ST UNIV · 2024 · $624,302 — PROJECT SUMMARY Social isolation is associated with excessive alcohol use, depression, anxiety, and other poor outcomes (e.g., Daeppen et al., 2013; Moos et al., 2001; Muller et al., 2017; Zuckermann et al., 2020). Substantial variability also exists in these associations, such that individuals with…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Daniel Max Crowley · PENNSYLVANIA STATE UNIVERSITY, THE · 2024 · $683,168 — Project Summary The proposed study will evaluate the economic impact of a major NIDA-funded prevention delivery and support system for evidence-based preventive interventions (EBPIs) known as PROSPER (PROmoting School/community-university Partnerships to Enhance Resilience). This research will build…