Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
STEPHEN R RAPP · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2024 · $1,288,706 — Project Summary This multi-site R01 aims to validate video-administered cognitive assessments for use by the Alzheimer’s Disease Research Centers (ADRCs) and other research programs whose activities have been interrupted by the COVID-19 pandemic, as well as for use in future initiatives when remote …
Homer L Twigg · INDIANA UNIVERSITY INDIANAPOLIS · 2024 · $752,410 — Project Summary/Abstract As of February 8, 2023 more than 102.7 million cases of SARS-CoV-2 infection leading to COVID-19 disease have occurred in the United States. Besides the acute morbidity and mortality associated with hospitalization, many patients with COVID-19 develop prolonged complication…
Haian Fu · EMORY UNIVERSITY · 2024 · $782,142 — PROJECT SUMMARY The World Health Organization (WHO) declared Mpox (MPX) a global health emergency in 2022 and in the United States, MPX was declared a Public Health Emergency with >30,500 cases confirmed so far. MPX is a zoonotic infectious disease caused by the orthopoxvirus Mpox virus (MPXV), whi…
Hugo Javier Aparicio · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $667,131 — PROJECT SUMMARY Social isolation, loneliness, and social environment continue to emerge as important factors in Alzheimer’s disease and related dementias (ADRD), more so with the COVID-19 pandemic and observed trends in the prevalence of social isolation, loneliness, and ADRD. Although there is incr…
Matthew Scott Kelly · DUKE UNIVERSITY · 2024 · $105,500 — ABSTRACT SARS-CoV-2, the etiological agent of COVID-19, has been responsible for more than 600 million reported infections and 6.5 million deaths globally. Although several antivirals, monoclonal antibodies, and immunomodulatory treatments improve patient outcomes, mortality from COVID-19 remains un…
Katarina Guttmannova · UNIVERSITY OF WASHINGTON · 2024 · $75,167 — ABSTRACT This is an administrative supplement to the parent study that examines changes in cannabis, alcohol, and tobacco use and related health risk behaviors (e.g., driving while—or riding with a driver—under the influence of cannabis, alcohol, and simultaneous effects of cannabis and alcohol) dur…
Xuanhong Cheng · LEHIGH UNIVERSITY · 2024 · $390,178 — Transcriptional profiling of proliferative skeletal muscle mononucleated cells coupled with broadband electrical cytometry towards diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome PROJECT SUMMARY / ABSTRACT Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating,…
OTTO Z ZHOU · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $351,601 — Bedside 3D diagnostic imaging in ICU ABSTRACT Imaging in intensive care unit (ICU) is an integral part of patient management. Bedside chest x-ray radiograph (CXR) is the most often requested imaging examination for the commonly encountered pulmonary diseases in the ICU and is also routinely used fo…
Keenan Wiggins · EMORY UNIVERSITY · 2024 · $27,093 — Project Summary: It is important for an organism to develop a strong defense to repel an infection, which means the organism must fine tune its immune system to provide efficient clearance of the pathogen. Reponses to these different pathogens can be further divided to long lasting protection and sh…
Julie May Croff · OSU CENTER FOR HEALTH SCIENCES · 2024 · $70,943 — Project Summary/Abstract Neurodevelopmental processes are shaped by dynamic interactions between genes and environments. Maladaptive experiences early in life can alter developmental trajectories, leading to harmful and enduring developmental sequelae. Pre- and postnatal hazards include maternal sub…
Chang Yoon Moon · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $42,724 — PROJECT SUMMARY In the first 6 months after COVID-19 vaccine approval, 3.4 billion doses were administered globally, potentially saving 7.2 million lives. Lipid nanoparticle (LNP)-mRNA based COVID-19 vaccines have been able to induce both a strong T cell- and antibody-mediated responses against SARS…
Elizabeth Somsen · EMORY UNIVERSITY · 2024 · $48,974 — PROJECT SUMMARY/ABSTRACT Influenza viruses are a constant public health threat. Their high mutation rates, combined with a large number of infections each year, generate novel variants; additionally, novel influenza viruses from animal reservoirs like swine and wild birds can occasionally infect hum…
Diana Bouhassira · JOHNS HOPKINS UNIVERSITY · 2024 · $102,932 — PROJECT SUMMARY/ABSTRACT In-hospital mortality rates for acute respiratory failure (ARF) have improved, resulting in increasing numbers of ARF survivors. While their survival is indicative of major clinical advances in care, many of these individuals are left with long-term physical, cognitive, and …
Ligia M. Chavez · UNIVERSITY OF HAWAII AT MANOA · 2024 · $648,132 — PROJECT SUMMARY/ABSTRACT Intense natural disasters including hurricanes, floods, and earthquakes have become more frequent and closely spaced in recent years. Large scale natural disasters can severely damage and degrade health care facility structural integrity and equipment, create environmental h…
Cathy Ann Alessi · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · 2024 — Background: The most frequently diagnosed sleep disorder among older Veterans is obstructive sleep apnea (OSA), which is associated with serious adverse effects on health, quality of life and survival. Positive airway pressure (PAP) is recommended as first-line treatment (particularly for moderate t…
JEFF T HUTCHINS · INHALON BIOPHARMA, INC. · 2024 · $1,024,926 — Project Summary Respiratory Syncytial Virus (RSV) is the leading cause of viral hospitalization and death in infants and young children, and also a major cause of respiratory illness in immunocompromised and elderly. Unfortunately, for the millions infected with RSV each year, there is no currently …
Risha Gidwani Marszowski · UNIVERSITY OF COLORADO DENVER · 2024 · $728,784 — Enrollment in high deductible health plans (HDHPs) has increased 50% in the past 5 years, with more than 45% of privately-insured Americans enrolled in such plans. HDHPs require patients to pay 100% of the costs of most care (excluding some primary or secondary preventive care) out of pocket until a…
Farshad Tehrani · ACTIOX LLC · 2024 · $55,000 — Opioid overdose is a significant public health problem that has been escalating in recent years. Based on the statistics from the Centers for Disease Control and Prevention (CDC), the number of overdose-related deaths surpassed 100,000 from April 2020 to April 2021. This is a significant increase in…
Jerica M Berge · UNIVERSITY OF COLORADO DENVER · 2024 · $549,281 — ABSTRACT Food insecurity is known to be associated with metabolic and cardiovascular disease in adults. However, there is a gap in our knowledge; specifically a lack of studies investigating factors that influence the emergence of cardiometabolic risks from food insecurity during childhood and adole…
JOSEPH E. GAUGLER · UNIVERSITY OF MINNESOTA · 2024 · $235,264 — Project Abstract Descriptive research suggests that living alone with cognitive impairment (CI) is associated with many complex challenges, such as a lack of available and accessible services to facilitate living independently, and an elevated risk of hospitalization and institutionalization. Addit…