Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
BRUNO DE BEZERRIL ANDRADE · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $3,960,184 — TB-RICC 3.0 is designed to support the Regional Prospective Observational Research Tuberculosis (RePORT) Consortium to produce the highest quality observational and interventional research on tuberculosis (TB), TB-HIV, and TB-COVID-19. To accomplish this goal, TB-RICC 3.0 will: i) collaborate with R…
Andrea S Foulkes · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $419,861 — Project Summary This proposal aims to develop, evaluate and disseminate novel statistical tools for rigorous investigation of the clinical spectrum, biological underpinnings and social determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, COronoVIrus Disease (COVID-…
KJ Suda · VETERANS HEALTH ADMINISTRATION · 2024 — Background: Few of the drugs Veterans take as a cornerstone to prevent and treat disease are produced domestically; the majority of medications consumed in the U.S. are produced in foreign facilities. Thus, the drug supply chain is global and susceptible to disruption due to unanticipated events, su…
GR Scott Budinger · JESSE BROWN VA MEDICAL CENTER · 2024 — Project Summary/Abstract Pulmonary fibrosis (PF) describes a group of disorders in which the alveolar space is progressively replaced by fibrotic tissue which eventually leads to death from respiratory failure. Available therapies modestly slow disease progression but are not curative, difficult to …
Thankam P Thyvalikakath · INDIANA UNIVERSITY INDIANAPOLIS · 2024 · $648,647 — Project Summary To avoid potential harm and improve dental treatment success, dental clinicians (DCs) must obtain an up-to- date medical and medication history of their patients. Recent studies have reported discrepancies with patient- reported medical histories in electronic dental records (EDRs), …
MARK Jay ALBERTS · YALE UNIVERSITY · 2024 · $494,611 — PROJECT SUMMARY/ABSTRACT We propose to renew the Southern New England Partnership In Stroke Research, Innovation and Treatment (SPIRIT), a StrokeNet Regional Coordinating Center (RCC) anchored previously by 3 leading institutions: Yale School of Medicine, the Warren Alpert School of Medicine at Brow…
Peter B Allen · DPLEXBIO INC. · 2024 · $494,340 — Project Summary This proposed project aims to develop a new type of digital PCR platform which eliminates the need for uniform volumes and thereby reduces the complexity, cost, and run time of digital PCR while increasing its dynamic range. The result is a higher performance digital PCR system that …
Natalie Celia Tronson · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $195,000 — PROJECT SUMMARY More than 85 million cases of COVID-19 have been recorded in the US alone, and up to 40% of survivors report Long-COVID symptoms including cognitive impairments. Together with evidence that inflammation during adulthood increases risk for later cognitive decline, this raises the pro…
CONNIE Marie ULRICH · UNIVERSITY OF PENNSYLVANIA · 2024 · $246,682 — ABSTRACT This application responds to PAR-16-454: International Bioethics Research Training Program (D43) with a focus on bioethics research training in Tanzania. The need for doctoral-trained bioethics scholars and bioethics scholarship in low and middle-income countries (LMIC) is urgent. With the …
Melissa Dawn Bauman · UNIVERSITY OF CALIFORNIA AT DAVIS · 2024 · $3,124,965 — PROJECT SUMMARY - OVERALL Psychiatric illnesses, including schizophrenia, affect a significant proportion of the population, yet current treatments are only partially effective for many individuals and, in the case of SZ, do little to address disabling cognitive and negative symptoms. Thus, there is…
FRANCISCO A MORENO · UNIVERSITY OF ARIZONA · 2024 · $341,521 — The nation, including the state of Arizona with a population that is 38.5% Latino and Native American, suffers from tremendous health disparities contributed to, in part, by the absence of a diverse biomedical research and healthcare workforce. Never has there been a greater need for health equity t…
Natalie Hiromi Brito · NEW YORK UNIVERSITY · 2024 · $715,736 — PROJECT SUMMARY Societal consequences of the COVID-19 pandemic are unprecedented. The global community has been crippled by a public health emergency that has had deleterious health and economic impacts, the scope of which has yet to be determined. As a result of the current crisis, pregnant women a…
Lun-Ching Chang · FLORIDA ATLANTIC UNIVERSITY · 2024 · $199,661 — ABSTRACT Florida Atlantic University (FAU), the University of Miami (UM) and Florida International University (FIU) propose a six-week Florida Summer Institute in Biostatistics and Data Science (Florida SIBDS) focused on health disparities related to cardiovascular and infectious diseases. Currently…
Valerie Chock · STANFORD UNIVERSITY · 2024 · $331,108 — PROJECT SUMMARY The Division of Neonatal and Developmental Medicine at Stanford University submits a competing renewal application to participate in the NICHD Neonatal Research Network (NRN). The Division and its faculty members have a long history of innovative research accomplishments in neonatal …
CHARLES J NEIGHBORS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $726,809 — Project Summary Transition-age (TA) adulthood—between ages 18 to 25—is a distinct and critical developmental period where unique biological, psychological, and social changes are occurring. Brain development continues into the latter part of this period, with neurological structures associated with …
TIMOTHY R DILLINGHAM · UNIVERSITY OF PENNSYLVANIA · 2024 · $642,659 — About 10-20% of persons who contract SARS CoV-2 will experience persistent post-acute sequelae of SARS- CoV-2 infection (referred here as PASC). Given that persistent symptoms are heterogeneous with multisystem involvement, recent consensus recommendations suggest that a holistic rehabilitation prog…
Ethan John Anderson · UNIVERSITY OF IOWA · 2024 · $436,894 — ABSTRACT: Sepsis is a dangerous hyper-inflammatory condition that carries a mortality rate of 25% for uncomplicated cases and rises to 80% for patients who develop multiple organ dysfunction syndrome (MODS). No specific therapies for MODS exist, which is why identification of druggable targets and b…
Susan Napier Thomas · GORDON RESEARCH CONFERENCES · 2024 · $9,000 — Project Summary/Abstract Immunoengineering is a vibrant, emerging field that improves human health by enabling the analysis, manipulation, and engineering of the immune system. Grounded in fundamental immunology discoveries, the integration of principles from engineering and the physical sciences in…
Lindsey A Miles · SCRIPPS RESEARCH INSTITUTE, THE · 2024 · $460,000 — Project Summary/Abstract The plasminogen activation system extensively regulates the inflammatory response in a broad range of tissues. Inflammation is essential for maintenance of normal tissue homeostasis and its dysregulation has a broad pathologic impact, including development of fibrosis, scar…
HONGMIN LI · LYCHEE BIOSCIENCE LLC · 2024 · $299,985 — Abstract: The recent outbreak of SARS-CoV-2 has caused severe economical and humanitarian loss worldwide after it first emergence in Wuhan, China in 2019. The genetic material of this virus is comprised of enveloped, positive- sense, single-stranded RNA. SARS-CoV-2 genome is evolutionary related to …