Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
CECILY V BISHOP · OREGON STATE UNIVERSITY · 2024 · $10,000 — PROJECT SUMMARY In September 2024, the 19th Northwest Reproductive Science Symposium (NWRSS) meeting will be hosted by Oregon State University at the OSU-Cascades campus in Bend, OR. This long-standing series began in 1989 as the Washington State University (WSU) and the University of Idaho (UI) an…
Katia Bruxvoort · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $619,863 — SUMMARY/ABSTRACT HIV is declining in many parts of the world, but rising in Latin America, including Brazil. From 2010 to 2019, the number of new HIV infections in Latin America increased 21%, compared to a global reduction of 23%. The number of reported HIV cases in Brazil increased from 13,719 in …
Livia Agnes Veress · CMTX BIOTECH, INC. · 2024 · $299,993 — PROJECT SUMMARY/ABSTRACT CMTx Biotech is a drug development company working to commercialize a pipeline of proprietary, non- antibiotic, chemically-modified tetracycline (CMT) compositions and formulations for the host-modulatory treatment of diseases with high unmet needs, including a proprietary, …
Sarah T Stahl · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $90,746 — PROJECT SUMMARY/ABSTRACT My ongoing research (R01 MH118270) examines the efficacy of a digital health intervention to stabilize the 24- hour rhythm of sleep, meals, and physical activity for reducing symptoms of depression in acutely-bereaved older adults. The onset of COVID-19 in 2020 occurred in t…
Arjun Rustagi · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $175,510 — PROJECT SUMMARY COVID-19 remains an ongoing global health crisis, in part due to emerging variants. Fundamental questions remain about the mechanisms by which SARS-CoV-2 infection drives inflammation in the lower lung, in part due to the lack of in vitro infection models. Better understanding of var…
Dawon Baik · UNIVERSITY OF COLORADO DENVER · 2024 · $75,600 — PROJECT SUMMARY/ABSTRACT My career goal is to establish an independent aging research program focused on designing and evaluating high quality, technology-based behavioral health interventions to improve self-management and quality of life (QoL) of community-dwelling older adults, particularly older…
Elisabeth Mates · VA SIERRA NEVADA HEALTH CARE SYSTEM · 2024 — Background: Thiamine deficiency (TD) causes a variety of thiamine deficiency disorders (TDDs) such as neuropsychiatric disturbances, polyneuropathy, ataxia, weakness and falling, and non-ischemic heart failure. Left untreated, TD can be associated with poor quality of life, loss of independence, and…
Louis M Mansky · UNIVERSITY OF MINNESOTA · 2024 · $84,171 — Human T-cell leukemia virus (HTLV-1) has been estimated to infect 15-20 million individuals worldwide and is known to be the etiological agent of an adult T-cell leukemia/lymphoma (ATLL), an inflammatory disease syndrome known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a…
Justin Berk · RHODE ISLAND HOSPITAL · 2024 · $65,365 — PROJECT SUMMARY This K23 application proposes novel research in opioid use disorder (OUD) treatment in a correctional healthcare setting and a robust training plan to support the successful transition of the Dr. Justin Berk, MD MPH MBA (PI) to independent clinician-scientist. His background in publ…
Naleef Fareed · OHIO STATE UNIVERSITY · 2024 · $186,244 — Project Summary The opioid crisis in the United States has reached a critical stage, with unprecedented levels of illness and death. In 2021, over 106,000 individuals died from drug overdoses, with opioids contributing to more than 80,000 of these deaths, accounting for 75% of all drug-related fatal…
Yizhou Dong · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $62,718 — PROJECT SUMMARY A vaccine is a promising approach for stopping the spread of HIV infections. Although vaccine regimens in clinical trials show various levels of protection against HIV, there is no effective vaccine available for a large population yet. Preclinical and clinical data demonstrate the i…
BRUCE Steven KLEIN · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $285,674 — ABSTRACT: Pre-existing T cell responses have been correlated with decreased disease severity and positive clinical outcomes during the influenza pandemic of 2009 and the recent COVID-19 pandemic. Therefore, diversifying T cell responses, particularly targeting conserved internal viral proteins such …
Chawangwa Modongo · UNIVERSITY OF CALIFORNIA-IRVINE · 2024 · $145,607 — Project Summary The emergence and spread of SARS-CoV-2 variants of concern is threatening global health and our ability to prevent COVID-19 disease, raising concerns about a potential new wave of the pandemic. HIV may complicate the trajectory of the COVID-19 pandemic and efforts to eradicate the vi…
JAMES E Robinson · TULANE UNIVERSITY OF LOUISIANA · 2024 · $310,000 — ABSTRACT The SARS-CoV-2 virus, the causative agent of COVID-19, has infected a reported 13,810,247 persons globally as of July 16, 2020 with a mortality rate of 4.2%. In the State of Louisiana, over 7.3% of the 86,411 COVID-19 cases involve people living with cancer. Treatment with convalescent seru…
Adolfo Garcia-Sastre · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $599,601 — Project Summary/Abstract The Mount Sinai U54 continues to accrue new lung cancer (LC) patients to its large, highly annotated longitudinal cohort with routine specimen collection. Updated research focus areas include: 1) the ability of patients with lung cancer to maintain robust immune responses to…
PATRICE DELAFONTAINE · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $9,869,052 — ABSTRACT – The Center for Clinical and Translational Science (CCTS), the CTSA Hub at the University of Alabama at Birmingham (UAB), serves a region of the country with a disproportionate burden of multiple chronic diseases and health disparities. The COVID-19 pandemic brought into sharp relief the c…
Libin Xu · UNIVERSITY OF WASHINGTON · 2024 · $648,691 — Benzalkonium chlorides (BACs) are widely used antimicrobials in disinfecting products, medical products, and food processing industries, suggesting humans may be exposed chronically to BACs through various routes. The ongoing COVID-19 pandemic has led to greatly increased use of disinfectants, resul…
Kate L Lapane · UNIV OF MASSACHUSETTS MED SCH WORCESTER · 2024 · $804,301 — This proposal is responsive to PAR-19-373 and the National Institute on Aging Strategic Plan Goals B and C. Social connectedness, the relationship people have with others, contributes to thriving in nursing homes. Loneliness is prevalent in nursing homes, and more so in residents with Alzheimer’s di…
Meghan Elizabeth Flanigan · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $104,106 — The COVID-19 pandemic has greatly exacerbated rising patterns of excessive alcohol consumption, particularly in women. Binge alcohol drinking is the most common pattern of excessive alcohol drinking and is associated with increased risk of developing mood disorders and Alcohol Use Disorder (AUD). So…
Fiona C Baker · SRI INTERNATIONAL · 2024 · $658,480 — PROJECT SUMMARY / ABSTRACT Initiating excessive alcohol drinking during adolescence is known to disturb typical neurodevelopmental patterns, increase the risk of developing alcohol use disorder (AUD), and accelerate involutional processes in adulthood. In response to RFA-AA-21-007, this application …