Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
DAVID P OLSON · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $59,898 — Abstract The postdoctoral Pediatric Endocrinology and Diabetes Training Program at the University of Michigan is designed to recruit and provide high quality research training in one of two major tracks, Basic Science or Clinical Investigation & Epidemiology to qualified candidates. Now on its 15th …
Melissa E Dichter · PHILADELPHIA VA MEDICAL CENTER · 2024 — Background. The suicide rate among women Veterans has increased substantially in recent years, particularly among younger women and those with limited or no engagement in Veterans Health Administration (VHA) care. The U.S. Department of Veterans Affairs (VA) has invested extensive resources toward p…
KAREN Suzanne MITCHELL · VA BOSTON HEALTH CARE SYSTEM · 2024 — Background Eating disorders (EDs) likely affect a significant proportion of female and male Veterans; however, they remain understudied and under-treated in VA. Individuals with EDs are likely to be high users of medical care, which is at least partly due to the physical complications of EDs. Noneth…
Eszter Boros · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $187,715 — Precision medicine requires tools that visualize diseased cells to enable diagnosis, facilitate surgical resection, and monitor therapeutic response. Technologies to identify the interface of cancer and healthy tissues require the ability to illuminate cancer cells with exceptional selectivity over …
Keri Lyn Rodriguez · VETERANS HEALTH ADMINISTRATION · 2024 — Quality of life following surgery is critically important to Veterans, their families, and the VA Healthcare System—especially for frail patients who are less likely to be discharged to home, more likely to be readmitted within 30 days, and have substantially increased rates of postoperative mortali…
Hsiao-Lan Wang · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $553,076 — Project Summary/Abstract Among head and neck cancer (HNC) patients, 92% report fatigue and 73% have pain. A 10% increase in fatigue or pain is associated with a 10-25% reduction in HNC survival. During the critical transition period from the end of active treatment to 3 months post-treatment (during…
STEVEN M. ASCH · MICHAEL E DEBAKEY VA MEDICAL CENTER · 2024 — Background: Advanced liver disease (AdvLD) is a serious illness that disproportionately affects Veterans. As many as half of AdvLD patients die within 2 years of developing liver complications, and nearly all suffer increasing symptoms and hospitalizations. Although many patients hope for curative l…
Adriaan Willem Bruijnzeel · UNIVERSITY OF FLORIDA · 2024 · $343,125 — SUMMARY Smoking is addictive and most smokers would like to quit. However, even with treatment, only a small percentage of smokers quits successfully. Clinical studies indicate that smoking cessation leads to anhedonia, which increases the risk for relapse. Nicotine induces the release of dopamine (…
Kara A Bernstein · UNIVERSITY OF PENNSYLVANIA · 2024 · $451,972 — Project Summary/Abstract: Accurate repair of DNA damage is critical for genetic stability, and for preventing aging-related degeneration and cancer. We are working to identify key factors that regulate accurate repair of DNA double-strand breaks (DSBs) through the error-free homologous recombination…
Stephanie Leah Shimada · EDITH NOURSE ROGERS MEMORIAL VETERANS HOSPITAL · 2024 — Background: Type 2 Diabetes, a common, complex condition with high comorbidity, affects 24% of Veterans. Vulnerable Veterans (e.g., African-American, rural, comorbid mental health diagnosis, low-income) are less likely to have controlled diabetes, and have higher mortality and morbidity compared to …
Robert F. Kirsch · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · 2024 — The Center on Functional Electrical Stimulation (FES Center) is a global leader in neurostimulation and neuromodulation research that addresses the unmet rehabilitation needs of Veterans and civilians with neurological, autonomic, psychiatric, pain, and other disorders. The Vision of the FES Center …
SCOTT W. LOWE · SLOAN-KETTERING INST CAN RESEARCH · 2024 · $463,686 — Genome characterization has enabled the cataloging of genes altered in human tumors and stimulated the development of therapies that exploit these alterations. Still, functional studies are ultimately needed to interpret and exploit the genetic variation that exists in human cancers. Furthermore, it…
Wendy McKelvey · FUND FOR PUBLIC HEALTH IN NEW YORK, INC. · 2024 · $192,587 — Project Summary/Abstract It is estimated that there are almost 1.5 million cases of foodborne illness (FBI) in New York City (NYC) each year, and more than 6,000 cases are serious enough to require hospitalization. Out of the 27 FBI outbreaks in NYC that were reported to the CDC National Outbreak Re…
Rebecca Ivy Hartman · VA BOSTON HEALTH CARE SYSTEM · 2024 — Malignant melanoma is one of the top five cancers in Veterans. If diagnosed early, like the majority of melanomas in the U.S., it is highly curable with local surgery alone in the outpatient setting. In contrast, clinically aggressive melanoma, defined in this proposal as tumor stage pT1b, requires …
Yaguang Xi · SOUTHEAST LOUISIANA VETERANS HEALTH CARE · 2024 — PROJECT SUMMARY: In the United States, approximately 3% of cancer patients are being treated in the Veterans Affairs Medical Centers (VAMCs) each year, of which 11% are colon or rectal malignancies. Colorectal cancer (CRC) remains a leading cause of cancer-related death in the United States. Althoug…
Carrie Lynn Esopenko · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $642,640 — Intimate partner violence (IPV), the physical violence, sexual violence, psychological aggression, or stalking by a current or former intimate partner, is a significant public health concern affecting approximately 10 million people in the United States annually. Approximately 33% of women exposed t…
George Dimopoulos · JOHNS HOPKINS UNIVERSITY · 2024 · $749,082 — SUMMARY Arboviruses remain an immense public health threat, causing yearly large epidemics. The overarching aim of this research is to better understand the role of the Aedes aegypti RNA interference (RNAi) pathway in antiviral defense and innate immunity, and to generate knowledge and tools for th…
Shobhan Gaddameedhi · NORTH CAROLINA STATE UNIVERSITY RALEIGH · 2024 · $367,565 — Circadian clock disruption: A risk factor for environmental carcinogenesis Abstract/Summary Circadian clocks respond to environmental time cues to coordinate 24-hour rhythmicity in gene expression and biological processes in virtually all cells of the body. According to the US Department of Labor, …
Nicholas Varvel · EMORY UNIVERSITY · 2024 · $331,013 — Project Summary/Abstract Status epilepticus (SE) is a frequent neurological emergency that can reduce the quality of life of those affected, produce cognitive deficits, and result in the development of epilepsy. Brain inflammation is an invariable feature of seizure activity and is believed to contr…
Marc Mendillo · NORTHWESTERN UNIVERSITY AT CHICAGO · 2024 · $326,284 — PROJECT SUMMARY/ABSTRACT Triple-negative breast cancer (TNBC) refers to a collection of heterogeneous breast tumors that lack expression of immediately druggable molecules, such as the estrogen and progesterone receptors and human epidermal growth factor receptor 2. No targeted therapy is currently …