Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Mikael Rubin · PALO ALTO UNIVERSITY · 2024 · $335,000 — Project Summary (Abstract) Social anxiety is a prevalent mental health concern that impacts approximately 12% of the US population. Yet, the majority of individuals with social anxiety do not receive treatment in large part because it is difficult to access mental health resources. There is a need f…
Kristopher Andrew Sarosiek · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · 2024 · $346,614 — ABSTRACT Central nervous system (CNS) tumors are a leading cause of cancer death and morbidity in children. CNS tumors, including the most common subtype – medulloblastomas, are routinely treated with external beam radiation therapy (xRT) as well as neurosurgery and chemotherapy, and improvements in…
Kathryn Elizabeth Evans · HARVARD MEDICAL SCHOOL · 2024 · $53,974 — Project Summary The central goal of this proposal is to characterize the role of the insular cortex (InsCtx) in encoding and shaping the physiological drive to consume nicotine in nicotine-dependent mice. The InsCtx integrates sensory, visceral, and limbic information and is implicated in interocept…
Ashley Elizabeth Walker · UNIVERSITY OF OREGON · 2024 · $398,361 — PROJECT SUMMARY As the prevalence of late-onset Alzheimer’s disease continues to increase, understanding the mechanistic causes of this disease is becoming increasingly critical. Recent clinical studies have linked increased stiffness of the large arteries to both impaired memory and Alzheimer’s dis…
Habibul Ahsan · UNIVERSITY OF CHICAGO · 2024 · $292,583 — ABSTRACT: This is the renewal U2R application for the “Bangladesh Center for Global Environmental and Occupational Health (GEOHealth)”- awarded along with the linked U01 grant in 2015 to the University of Chicago (UofC) and International Centre for Diarrheal Disease Research, Bangladesh (ICDDR,B). T…
Jithin Yohannan · JOHNS HOPKINS UNIVERSITY · 2024 · $191,187 — ABSTRACT This is an application for a K23 Mentored Patient-Oriented Research Career Development Award. The goal of this proposal is to provide the candidate with the advanced skills needed to establish an independent research program in the area of glaucoma diagnostic testing with special expertise…
Robert K Ernst · UNIVERSITY OF MARYLAND BALTIMORE · 2024 · $463,500 — PROJECT SUMMARY Infectious diseases have a substantial global health impact. Clinicians need rapid and accurate diagnoses of infections to direct patient treatment and improve antibiotic stewardship, but current methodologies face severe limitations in this regard. In the first funding cycle of our …
Shari Pilon-Thomas · H. LEE MOFFITT CANCER CTR & RES INST · 2024 · $452,237 — Summary Bladder cancer is the fourth most common cancer in men and a leading cause of cancer mortality among men and women with the rates of bladder cancer incidents and bladder cancer-related deaths that have not decreased over the last 40 years. Therefore, novel more precise treatment strategies a…
Katherine J. Karriker-Jaffe · RESEARCH TRIANGLE INSTITUTE · 2024 · $783,430 — PROJECT SUMMARY/ABSTRACT Excessive drinking results in tremendous economic and social costs and is a leading cause of preventable death in the US. Only a small minority of people with alcohol use disorder (AUD) receive appropriate services, and there are large disparities in access to alcohol health…
Matthew Brown · BROAD INSTITUTE, INC. · 2024 · $93,982 — PROJECT SUMMARY/ABSTRACT The loss of glucose-stimulated insulin secretion (GSIS) is a critical pathophysiological event precipitating development of hyperglycemia in Type 2 diabetes mellitus (T2DM). Recent evidence suggests that loss of GSIS in diabetes is associated with metabolic reprogramming tow…
Bethany Plakke Anderson · KANSAS STATE UNIVERSITY · 2024 · $71,589 — PROJECT SUMMARY Autism spectrum disorder (ASD) is a neurodevelopmental disorder where individuals exhibit deficits in cognitive flexibility. Purpose: This proposal will record from the frontal cortex of Fmr1 KOs (model of Fragile X syndrome) during cognitive flexibility tasks and assess how neural h…
Juliet Iwelunmor · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $605,834 — Project Abstract Access to highly active antiretroviral treatment led to increased survival of people living with HIV (PLWH) in Africa, which in turn increased their CVD burden. PLWH now experience high CVD-mortality probably due to uncontrolled hypertension (HTN). Based on Global Burden of Disease …
PETER L FRANZEN · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $776,721 — ABSTRACT Suicide is the second leading cause of death among young people age 14–24, and rates in this age group are increasing. Most suicide risk factors are distal (i.e., long-standing, static), thus informative regarding who is at risk, but not when. As such, our ability to reliably predict near-t…
Lora Lynn Iannotti · WASHINGTON UNIVERSITY · 2024 · $620,841 — ABSTRACT A disturbingly high number of young children around the world experience stunted growth and development with irreparable consequences through the lifespan. Recent estimates show 250 million children less than five years of age are not reaching their developmental potential, and 151 million…
Cody Welford Thompson · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · 2024 · $470,518 — Project Summary/Abstract Without T cells (e.g., CD4+ helper, CD8+ cytotoxic), mammals cannot have a proper functioning immune system or fight off viral infection. Classically, T cells in mammals develop in the thymus then migrate to peripheral tissues and circulate in the blood. Development of T ce…
Bradley Joel Undem · JOHNS HOPKINS UNIVERSITY · 2024 · $919,316 — Project Summary/ Abstract Basic and clinical research over the past decade is shedding new light on the major role played by the nervous system in respiratory pathophysiology, in particular in the “hypertussivity” associated with chronic unproductive cough, in the “airways hyperresponsiveness”” asso…
John A. Dani · UNIVERSITY OF PENNSYLVANIA · 2024 · $535,555 — Project Summary. Cocaine is the most widely abused psychostimulant by a wide margin, and it remains a major public health problem in the US. Cocaine use was slowly declining, but in recent years there has been a resurgence in cocaine abuse accompanied by a sharp increase in cocaine-related hospital…
Paul Wesley Noble · CEDARS-SINAI MEDICAL CENTER · 2024 · $830,589 — ABSTRACT Our laboratory has been focused on elucidating the molecular mechanisms that regulate progressive pulmonary fibrosis for over two decades. My contributions to the field of idiopathic pulmonary fibrosis research include using matrix hyaluronan as a model molecule to dissect the molecular mec…
Juan Pablo Arroyo Ornelas · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $158,436 — Chronic Kidney Disease (CKD) affects 15% of the US adult population 30 and vasopressin is associated with progression of non-diabetic, diabetic, and polycystic kidney disease (PKD). 1-18 However, the specific mechanism(s) through which vasopressin worsens progression of kidney disease are unclear. V…
Carolyn Stigge Harris · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $161,556 — PROJECT SUMMARY/ABSTRACT The psychological symptom cluster is a common problem that impacts women receiving breast cancer treatment and is associated with several negative outcomes, including reduced functional status and quality of life. Unfortunately, the mechanism(s) that underlie this cluster ar…