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9873 documents

COVID-19 and Nail Salon Workers: Taking Stock of the Pandemic's Impact on Occupational Health and Safety

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Marie-Anne Sanon Rosemberg · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $79,176 — PROJECT SUMMARY/ABSTRACT: The 400,000 nail salon workers (NSW) in the U.S.—primarily immigrant women in their prime reproductive years—are part of a $10 billion small business industry that is understudied and hard-to-reach. NSWs are emblematic of low-wage, underinsured, immigrant women in the workf…

Reducing Evictions, Homelessness, and Poor Health Outcomes Among Washington State Veterans: Integrating Novel State Data into Analytic and Predictive Models of Housing Insecurity

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Steven Bacchus Zeliadt · VA PUGET SOUND HEALTHCARE SYSTEM · 2024 — Background: There is a paucity of reliable, household-level data on evictions. We have no data on how many Veterans are evicted each year, whether they regain housing or not after eviction, or the costs to VA of rehousing evicted Veterans and treating eviction-related health conditions. If we knew t…

Generalizing Effects of Infectious Disease Prevention Interventions in the Presence of Interference

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Bonnie E Shook-Sa · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $169,811 — PROJECT SUMMARY Medical and behavioral interventions are critical for preventing the spread of infectious diseases. But there are statistical challenges when estimating causal effects for such interventions. Most statistical methods assume the treatment of one individual does not affect outcomes of …

Preclinical development of a synthetic lung surfactant dry powder aerosol for hypoxemia or acute respiratory distress syndrome patients receiving different modes of ventilation support

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

P. Worth Longest · VIRGINIA COMMONWEALTH UNIVERSITY · 2024 · $733,241 — Hypoxemia and acute respiratory distress syndrome (ARDS) arising from direct lung injury are associated with a dysfunctional lung surfactant system; however, large clinical trials of surfactant replacement therapy have been unsuccessful in this population. The method employed for surfactant delivery…

Applying a Targeted Machine Learning and Causal Inference Approach to Analyzing Long-Term Sequelae of COVID-19 Infection Through the National COVID Cohort Collaborative.

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Zachary Butzin-Dozier · UNIVERSITY OF CALIFORNIA BERKELEY · 2024 · $134,923 — Modified Project Summary/Abstract Section Candidate: I am an epidemiologist in the Division of Biostatistics at the University of California, Berkeley School of Public Health, and I completed my Ph.D. in Epidemiology in August 2022 at UC Berkeley. Since my graduation, I have worked with the Center f…

Investigating structural drivers of maternal and child health inequities: a geospatial and data science approach

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Aresha Maree Martinez-Cardoso · UNIVERSITY OF CHICAGO · 2024 · $126,486 — Abstract The United States ranks among the worst of all developed countries in perinatal health, including high rates of maternal and infant mortality and pervasive disparities among women who are racial/ethnic minorities, have lower SES, and reside in rural regions. Perinatal outcomes are influence…

Intranasal Vaccine Against Lyme Disease

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Maria Gomes-Solecki · IMMUNO TECHNOLOGIES, INC. · 2024 · $999,881 — ABSTRACT We propose to develop intranasal, parainfluenza 5 (PIV5) viral-vector delivered vaccines against human Lyme disease (LD) to be administered using a prime-boost schedule, for the US market. A recent new estimate of LD by the CDC places the new number at 476,000 annual cases, up from 329,000 …

Alzheimer's-focused Celdara Medical High-Potential Entrepreneurial Fellowship Program (A-CHEF)

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Julie H Coleman · CELDARA MEDICAL, LLC · 2024 · $162,000 — While the majority of biomedical scientists end up in professions outside of academia, most receive little-to-no training in preparation for this transition. Here, we seek to establish a comprehensive training program to prepare scientists for their actual careers: to meet the nation’s greatest biom…

2022-2024 US DOHaD Society Meetings

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

PHU V. TRAN · UNIVERSITY OF MINNESOTA · 2024 · $15,250 — ABSTRACT The fundamental concept of Developmental Origins of Health and Diseases (DOHaD), which posits that early- life events or exposures determine the health outcomes across the life span, has been well represented by the US DOHaD Society exemplified by its annual national meeting since its incep…

Predictors of Weight Loss and Weight Loss Maintenance to Lifestyle Modification Therapy and Pharmacotherapy for Adolescents with Obesity

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Amy C. Gross · UNIVERSITY OF MINNESOTA · 2024 · $357,024 — Project Summary/Abstract Neurobehavioral characteristics have the potential to predict initial weight loss and weight loss maintenance in response to various treatment approaches in adolescents with obesity. However, prior research is limited by heavy reliance on cross-sectional analyses and a focus…

DIALS: supporting structural biology through open source diffraction processing software

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Aaron Samuel Brewster · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · 2024 · $1,204,713 — Project Summary/Abstract X-ray crystallography is a powerful tool for determining the atomic positions of proteins, used by researchers at synchrotrons and X-ray free electron lasers. Typically, the crystal is exposed to X-rays, which diffract and are collected on a detector to create diffraction pa…

Brain Function and Neurogenomic influences on AUD risk and resilience.

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Chella Kamarajan · SUNY DOWNSTATE MEDICAL CENTER · 2024 · $507,544 — This COGA (Collaborative Study on the Genetics of Alcoholism) spinoff application aims to understand structural/functional features in key brain networks (Default Mode Network (DMN), Executive Control Network (ECN), Reward/Salience Network (RSN)) underlying the critical transition from regular drink…

The effects of immunosuppression on SARS-CoV-2 persistence, virus genetic diversity and clinical outcomes of COVID-19

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Mirella Salvatore · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $296,625 — ABSTRACT One of the biggest challenges for the development of Coronavirus Disease 2019 (COVID-19) vaccines and therapeutics is the emergence of SARS-CoV-2 variants with immune-escape or resistance mutations. Multiple evidence points to the chronic infection of immunocompromised hosts, especially ind…

The Impact of the COVID-19 Pandemic Environment on Cardiometabolic Health

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Shivani A Patel · EMORY UNIVERSITY · 2024 · $290,492 — PROJECT SUMMARY RELEVANCE: The COVID-19 pandemic upended life in the United States through social distancing policies, such as remote work mandates, to halt the spread of the SARS-CoV-2 coronavirus. Weight gain and changes in physical activity, dietary intake, and other health behaviors related to c…

Trajectories of Isolation and (A)Loneliness with AOD Use, 2019-2027: A National Egocentric Network Study of US Adults

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

MICHAEL SEAN POLLARD · RAND CORPORATION · 2024 · $637,163 — PROJECT SUMMARY This project will significantly advance understanding of the longitudinal links between social connection, alcohol, cannabis, and other drug (AOD) use through the analysis of novel longitudinal data that includes a multidimensional assessment of social connection over eight consecut…

Dynamic neural systems udnerlying social-emotional functions

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Lorenzo Pasquini · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $56,706 — Parent Project Summary Emotions are central to human functioning, guiding thought and action from the earliest to the latest days of life1–3. Emotional experiences change over the adult life span, with older adults shifting their motivational goals towards optimizing emotional regulation and reporti…

Mechanisms of macrophage death co-dependent on M. tuberculosis and IFN-a,b receptor

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

CARL Francis NATHAN · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $211,875 — ABSTRACT Mycobacterium tuberculosis (Mtb) was the world’s single leading cause of death from infection before COVID- 19. Direct-acting antimycobacterial regimens are long, often toxic and plagued by emergence of drug resistance. Adjunctive therapies could potentially speed the cure of tuberculosis b…

Interdisciplinary Health Equity Research (IHER) Center

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Sangeeta Gupta · DELAWARE STATE UNIVERSITY · 2024 · $43,301 — Interdisciplinary Health Equity Research (IHER) Center Summary The COVID-19 pandemic put a spotlight on our nation’s stark disparities in health and the disproportional burden of disease related to race, ethnicity, and socioeconomic status. Delaware is an ideal state for a health disparities-focuse…

Implementation of a triadic network case management intervention for younger Black sexual minority men

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Alida M Bouris · UNIVERSITY OF CHICAGO · 2024 · $691,176 — We will conduct a Hybrid Type II effectiveness-implementation randomized controlled trial of a Case Management Dyad (CM2) intervention, an evidence-based triadic social work intervention that uses a case manager dyad to engage younger Black sexual minority men (YBSMM) aged 18-35 in economic stabilit…