Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Yu Zuo · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $172,800 — PROJECT SUMMARY/ABSTRACT A growing body of evidence suggests that COVID-19 emulates many aspects of inflammatory and autoimmune diseases. Circulating autoantibodies have been detected in serum of COVID-19 patients where they have an antigen profile reminiscent of the lupus-associated thrombophilia k…
Christopher Bizon · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $787,035 — The proliferation of high-throughput technologies has led to previously unimaginable growth in biomedical research data sets and knowledgebases. Nearly all these data and knowledge sources address specialized areas of biomedical research, leading to natural diversity but also growing disintegration …
BRIAN R CRANE · CORNELL UNIVERSITY · 2024 · $1,018,507 — This is an R24 proposal to establish a Regional and National Resource in modern Electron-Spin Resonance (ESR) Technology for use by the biomedical community. This resource will build upon 20 years of a very successful National Biomedical Center: ACERT (funded by an NIH P41 grant), in which the new E…
Leonard E. Egede · MEDICAL COLLEGE OF WISCONSIN · 2024 · $212,052 — Project Summary/Abstract Structural racism, defined as the ways in which societies foster discrimination through mutually reinforcing inequitable systems, has emerged as an important social risk factor and contributor to poor health outcomes for racial/ethnic minorities (Egede 2020, Bailey 2017). S…
Erica Soltero · BAYLOR COLLEGE OF MEDICINE · 2024 · $149,334 — Project Summary Hispanic adolescents are disproportionately burdened by type 2 diabetes (T2D) and social determinants of health (SDoH), which can serve as barriers to behavior change and participation in disease prevention efforts. Telehealth is a potentially effective approach for delivering diseas…
Vladimir R Muzykantov · UNIVERSITY OF PENNSYLVANIA · 2024 · $653,281 — No anti-thrombotic agent (ATA) is safe and effective in the many patients at a combined risk of acute thrombosis and bleeding, e.g., in the early post-surgery period. To address this unmet need, we develop drug delivery systems (DDS) executing two main functions: A) Block access of ATA to off- targe…
Emily F Dauria · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $281,857 — Project Summary/Abstract There is a strong scientific premise for the study of integrated substance use disorders (SUDs) and HIV- prevention interventions for criminal justice-involved (CJI) populations. SUDs lead to increased rates of justice involvement as well as increased risk for HIV-acquisitio…
SAMUEL YANG · STANFORD UNIVERSITY · 2024 · $231,600 — PROJECT SUMMARY / ABSTRACT Neutrophils are the first line of host defense against invading pathogens that trap and kill pathogens through a process called NETosis. Upon stimulation by the pathogen, neutrophils extrude decondensed chromatin in the form of DNA fibers that trap invading cells and forms…
Leena Bhattacharya Mithal · LURIE CHILDREN'S HOSPITAL OF CHICAGO · 2024 · $83,196 — Project Abstract Pregnant people are uniquely susceptible to SARS-CoV-2 infection, with risks of severe maternal COVID-19 illness and obstetric complications. However, far less is known about the long-term impact of pregnancy- associated SARS-CoV-2 infection on developing infants. Given the global b…
Ian Andres Boggero · UNIVERSITY OF KENTUCKY · 2024 · $125,910 — Chronic masticatory muscle pain disorders (MMPD) affect between 5-12% of the population, are the second most common musculoskeletal pain conditions after chronic low back pain, and are associated with management costs of over $4 billion per year, presenting a serious public health issue. Multidiscip…
Hui Shen · VAN ANDEL RESEARCH INSTITUTE · 2024 · $353,999 — PROJECT SUMMARY / ABSTRACT OC is the deadliest gynecological cancer in the US. It consists of several histotypes, each biologically distinct with different clinical challenges. In the first three and half years of the parent grant, in spite of challenges imposed by COVID, we were able to make subst…
KEJAL KANTARCI · UNIVERSITY OF MINNESOTA · 2024 · $615,261 — PROJECT SUMMARY/ABSTRACT Since the World Health Organization declared COVID-19 a pandemic in March 2020, increasing evidence has shown that the disease affects multiple organs, including the central nervous system (CNS). Effects of COVID-19 on the CNS in the acute phase were documented clinically, …
Robert Tarran · UNIVERSITY OF KANSAS MEDICAL CENTER · 2024 · $542,500 — PROJECT SUMMARY Cystic fibrosis (CF) is a genetic disease caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene. CF airways are immunocompromised and become colonized with bacteria soon after birth. Chronic bacterial infection leads to persistent and severe neutrophil-domina…
Sally Margaret Blower · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $773,130 — PROJECT SUMMARY / ABSTRACT This proposal is to develop and implement methods for quantifying geographic disparities, within Sub-Saharan African countries, in the opportunity for people living with HIV (PLHIV) to access antiretroviral therapy (ART); and to identify optimal strategies for reducing suc…
ROBERT A CLARK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2024 · $5,584,747 — Project Summary-Abstract South-Central Texas is home to San Antonio and Austin, both among the nation’s fastest growing cities. San Antonio, the gateway to South Texas, is the 7th largest city and the largest minority- majority Hispanic/Latino city in the US, whereas Austin is 11th largest. The regi…
Marcela V Horvitz-Lennon · RAND CORPORATION · 2024 · $796,338 — PROJECT SUMMARY Medicaid is a key player in the care of individuals living with serious mental illness (SMI). Despite its high costs, Medicaid-funded SMI care is characterized by low quality and inequities. Although state Medicaid programs have implemented policies to improve quality or value of car…
CYNTHIA M SUVEG · UNIVERSITY OF GEORGIA · 2024 · $624,590 — Modified Project Summary/Abstract Section Latin American children in the United States (U.S.) experience behavioral and physical health disparities early in development that persist into adulthood. Early in development, Latin American children are behind their peers in cognitive self-regulation (e.…
Seth Blumberg · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $403,750 — Elimination of an infectious disease is often a goal of the public health community. Although that goal is rarely achieved, the tremendous expansion of epidemiological databases provides new opportunities to test hypotheses concerning elimination with mathematical modeling. Besides improving our sci…
PHILIP J GOULDER · UNIVERSITY OF OXFORD · 2024 · $527,932 — IMPACT OF IMMUNE SEX DIFFERENCES IN THE FIRST 1000 DAYS OF LIFE AND IN CHILDHOOD AND ADOLESCENCE PROJECT SUMMARY: Substantial differences exist between the immune responses made by males and females that critically impact on health and survival. Immune sex differences start within weeks of concepti…
Nevan J Krogan · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $2,475,950 — THE HOST PATHOGEN MAP INITIATIVE 2.0 OVERALL SUMMARY The Host-Pathogen Map Initiative (HPMI) 2.0 is an interdisciplinary program that aims to improve our understanding of the interactions between host cellular systems and respiratory pathogens and builds upon the success of its previous iteration. T…