Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Goleen Samari · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $135,783 — PROJECT SUMMARY Adverse birth outcomes, such as preterm birth, low birth weight, and small for gestational age, have serious health consequences not just during infancy but across the life course. Past research shows an immigrant advantage in birth outcomes compared to women born in the United State…
Alyce Sophia Adams · KAISER FOUNDATION RESEARCH INSTITUTE · 2024 · $700,000 — Project Summary/Abstract Diabetes mellitus is a significant health burden in the U.S. and California leads the nation in incident cases and costs of Type 2 Diabetes. Individuals with low socioeconomic status, older adults, rural populations, and racial and ethnic minorities are at highest risk. The …
JEFFREY S GONZALEZ · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2024 · $810,000 — CENTER OVERVIEW The New York Regional Center for Diabetes Translation Research (NY-CDTR) is seeking is first competitive renewal in order to continue to maximize the assets devoted to diabetes translation research in the high-need, culturally diverse New York area. With this application, we expand o…
Hongsheng Gui · HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES · 2024 · $157,000 — PROJECT SUMMARY/ABSTRACT Technology is rapidly expanding our knowledge of the human genetic code and the alterations which predispose to disease; however, minority populations (e.g., African Americans) are rarely included in the discovery arms of genomic studies. As a particular genomic region, the …
Melissa Juliana DuPont · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $163,665 — PROJECT SUMMARY/ABSTRACT We propose a two-part integrated mixed-methods project to help improve our understanding of the social media landscape for adolescents, especially those with mental illnesses, and further accountability of new technology. Research has documented a concurrent adolescent menta…
TERRY L. SHEPPARD · KEYSTONE SYMPOSIA · 2024 · $17,700 — ABSTRACT Support is requested for a Keystone Symposia conference entitled HIV and (Re)Emerging Viruses: Aligning Lessons Across Pandemics, organized by Drs. Melanie Ott, Priti Kumar, Olivier Schwartz and Alex Sigal. The conference will be held in Hannover, Germany from April 8-11, 2024. This Keyston…
OLGA A AMOSOVA · ACTOPROBE, LLC · 2024 · $295,308 — Abstract: Understanding molecular mechanisms of diseases and manipulating them to achieve cure constitutes one of the "holy Grail" of biomedical science. Infectious (and parasitic) diseases are responsible for ~30% of premature deaths, especially in low- and middle-income countries. Studies of the p…
Alash'le G. Abimiku · INSTITUTE OF HUMAN VIROLOGY · 2024 · $249,896 — Project summary Antimalarial drug resistance is a continuing challenge in the global effort to control and eliminate malaria. Well designed, rapid and highly granular antimalarial surveillance systems are urgently needed to protect the efficacy of remaining antimalarial treatments and inform discove…
Jeffrey A Henderson · BLACK HILLS CTR/AMERICAN INDIAN HEALTH · 2024 · $1,046,042 — Mitakuye Oyasin is a well-known Lakota phrase that means “we are all related.” This phrase is often used to signify the Lakota people’s appreciation for and relationship with the environment (Unci Maka or Grandmother Earth). This Native American Research Centers for Health (NARCH) XII program applic…
Keith Thomas Gagnon · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2024 · $230,891 — PROJECT SUMMARY Messenger RNA, or mRNA, and its translation into protein lies at the heart of the central dogma of molecular biology. Converting this basic cellular mechanism into a therapeutic opportunity was the basis of the first two successful COVID-19 vaccines. This technology has the potentia…
Mahmoud Moradi · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · 2024 · $364,373 — PROJECT SUMMARY With recent advances in structural biology and supercomputing technology, all-atom molecular dynamics (MD) simulation technique has gained momentum as a prominent tool for the study of protein structural dynamics. Brute-force MD, however, is not capable of adequately sampling most fu…
JONATHAN S MALTZMAN · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · 2024 — ABSTRACT Immunosuppression required for lifesaving solid organ transplantation is complicated by significant morbidity including increased recurrence of latent viral infection in transplant recipients. Approximately 60-70 percent of adults in the United States are latently infected with Cytomegalovi…
Zandrea Ambrose · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $235,550 — SARS-CoV-2 is a novel b-coronavirus identified in 2019 that causes the disease COVID-19, which is responsible for over 6 million deaths since late 2019. While recent virology studies have clarified many aspects of how SARS- CoV-2 infects cells and causes disease, questions remain on the spatio-tempo…
KOREY K HOOD · JOSLIN DIABETES CENTER · 2024 · $119,527 — PROJECT SUMMARY/ABSTRACT Adolescents and young adults (AYA) with type 1 diabetes (T1D) are especially at risk for missed diabetes visits and suboptimal self-care behaviors, as evidenced by their poor glycemic control with very high A1c levels. Further, diabetes distress is common in AYA with T1D and…
Thomas G Brott · MAYO CLINIC JACKSONVILLE · 2024 · $1,284,994 — The broad, long-term objective of this application is to advance primary prevention of stroke in patients at risk for stroke due to atherosclerosis of the carotid artery. One to two percent of adults in the U.S. have asymptomatic atherosclerotic stenosis of the carotid artery exceeding 50% luminal …
BENJAMIN S ABELLA · UNIVERSITY OF PENNSYLVANIA · 2024 · $406,250 — The objective of the PHLHousing+ Evaluation is to test whether unconditional, monthly cash payments made directly to tenants increases housing security and thereby reduces health disparities for low-income renters who, in the city of Philadelphia, are disproportionately Black. This objective is alig…
Aditya Subhash Khanna · BROWN UNIVERSITY · 2024 · $207,669 — Project Summary Coronavirus Disease 2019 (COVID-19) continues to cause significant morbidity and mortality across the world. Characterized by crowded detention facilities and limited medical safety resources, US criminal legal settings (CLS) have experienced some of the largest COVID-19 outbreaks. P…
RISA B WEISBERG · BEHAVR, LLC · 2024 · $805,212 — Project Summary: The US is experiencing an opioid crisis, with an estimated 2.5 million Americans meeting full criteria for opioid use disorder (OUD). Medications for opioid use disorder (MOUD) like buprenorphine are currently the most effective form of intervention for OUD. In spite of the proven e…
Ricardo Rajsbaum · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $471,011 — The Severe Acute Respiratory Syndrome Coronavirus 2 (CoV-2) belongs to a family of pathogenic enveloped RNA viruses of the family Coronaviridae. The ongoing pandemic has caused a public health emergency worldwide, accompanied by dire health and economic consequences. There is evidence suggesting tha…
DANA P ASCHERMAN · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $237,514 — The current SARS-CoV-2 pandemic has had devastating consequences, with more than 110,000,000 cases and 2,400,000 deaths worldwide. Beyond the direct effects of SARS-CoV-2 infection, much of the morbidity and mortality stems from dysregulated activation of the immune system that culminates in systemi…