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Principal Investigator: Alyce Sophia Adams
Organization: KAISER FOUNDATION RESEARCH INSTITUTE
Fiscal Year: 2024
Award: $700,000
Funding agency: National Institute of Diabetes and Digestive and Kidney Diseases
Project Summary/Abstract
Diabetes mellitus is a significant health burden in the U.S. and California leads the nation in incident cases and
costs of Type 2 Diabetes. Individuals with low socioeconomic status, older adults, rural populations, and racial
and ethnic minorities are at highest risk. The drivers of these disparities include a complex combination of
interacting factors at the individual, family, community, health system, societal, and policy levels. Programs and
policies that can effectively translate high-quality, evidence-based diabetes interventions into widespread
practice across diverse communities, modes of delivery, and a range of settings are desperately needed. The
Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational
Research (DREAMS-CDTR) aims to advance health equity science through the development and translation
of: 1) innovations and structural changes to healthcare delivery systems that substantively reduce health
inequalities, and 2) innovative, scalable interventions to alter the socioenvironmental drivers of the Type 2
Diabetes epidemic and associated disparities.
Focusing on the northern California and Central Valley regions of California, the DREAMS-CDTR will conduct
clinical research and interventions designed to inform practice and policy change at the health system,
community and policy levels. The DREAMS-CDTR (formerly Health Delivery Systems) brings together
translational science core faculty who have expertise in diverse, multi-level areas including: food insecurity,
medication adherence, health communication, health IT, social policy, and cost effectiveness analysis.
DREAMS-CDTR will involve four regional academic sites with a range of public and non-profit health systems
that serve large and diverse populations: Kaiser Permanente Northern California’s Division of Research and
the University of California at San Francisco, Merced and Davis.
The DREAMS-CDTR activities include: an Administrative Core, Pilot and Feasibility Program, Enrichment
Program, and three coordinated research cores - Health Equity & Action Translational (HEAT) core, Methods
and Data Integration (MDI) translational core, and National Diabetes Policy Research Resource (DPR) core.
The HEAT Core will employ a multi-level systems approach to designing rigorous action-oriented observational
and interventional research. The MDI Core will systematically prepare and support DREAMS-CDTR members
in harnessing novel advances in methods and data to achieve greater health equity in Type 2 Diabetes. Lastly,
the novel National DPR Core will extend the reach of the DREAMS-CDTR expertise and resources beyond the
primary institutions in five key areas of expertise: (1) natural experiments research,(2) health economics,
including comparative effectiveness and cost-effectiveness analysis; (3) simulation modeling, (4) machine
learning, and (5) communicating science to policy-making institutions, community partners, health
departments, and human service organizations.
Terms: <Acceleration><Access to Care><Adult-Onset Diabetes Mellitus><Area><Attention><COVID-19 pandemic affected><COVID-19 pandemic consequence><COVID-19 pandemic effects><COVID-19 pandemic impact><COVID-19 pandemic impacted><California><Caring><Clinical><Clinical Research><Clinical Study><Communication><Communities><Complex><Complications of Diabetes Mellitus><Cost Effectiveness Analysis><Data><Department of Health and Human Services><Development><Diabetes Complications><Diabetes Mellitus><Diabetes-Related Complications><Diabetic Complications><Disparities><Disparity><Dreams><Epidemic><Equity><Faculty><Family><Fostering><Foundations><Funding><Future><Grant><Health><Health Care Systems><Health Inequity><Health Policy><Health Services Accessibility><Health equity research><Health system><Healthcare Delivery><Healthcare Systems><History><Improve Access><Individual><Individuals from minority><Individuals of minority><Inequalities in Health><Inequities in Health><Inequity><Institution><Intervention><Intervention Strategies><Intervention Studies><Investigators><Ketosis-Resistant Diabetes Mellitus><Low income><Machine Learning><Maturity-Onset Diabetes Mellitus><Methods><Minority Groups><Minority People><Minority Population><Minority individual><NIDDK><NIDDM><Names><National Institute of Diabetes and Digestive and Kidney Diseases><Natural experiment><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Observation research><Observation study><Observational Study><Observational research><Outcome><Paper><Pattern><Persons><Policies><Policy Making><Policy Research><Population Heterogeneity><Prevalence><Public Health><Public Health Practice><Publishing><R-Series Research Projects><R01 Mechanism><R01 Program><Recording of previous events><Research><Research Design><Research Grants><Research Methodology><Research Methods><Research Personnel><Research Project Grants><Research Projects><Research Resources><Research in health equity><Researchers><Resources><Rural><Rural Population><Rural group><Rural people><San Francisco><Science><Scientist><Site><Slow-Onset Diabetes Mellitus><Social Environment><Social Policies><Stable Diabetes Mellitus><Study Type><System><T2 DM><T2D><T2DM><Target Populations><Translating><Translational Research><Translational Science><Translations><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States Department of Health and Human Services><United States Dept. of Health and Human Services><Universities><Vulnerable Populations><Work><access to health services><access to services><access to treatment><accessibility to health services><adult onset diabetes><availability of services><base><bases><care access><care delivery><career><career development><community partners><community setting><community-based partners><comparative effectiveness><coronavirus disease 2019 pandemic consequence><coronavirus disease 2019 pandemic impact><cost><cost efficient analysis><cost-effective analysis><data integration><design><designing><developmental><diabetes><diabetes control><diabetes mellitus control><diabetes risk><disparity in health><diverse populations><drug adherence><drug compliance><effects following the COVID-19 pandemic><ethnic minority><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><evidence base><experiment><experimental research><experimental study><experiments><food insecurity><health and care delivery><health care delivery><health care policy><health communication><health delivery systems><health disparity><health economics><health equity><health equity promotion><health equity-focused research><health inequalities><health service access><health services availability><health services delivery><healthcare policy><heterogeneous population><high risk><histories><impact of the SARS-CoV-2 pandemic><improved><innovate><innovation><innovative><intervention design><intervention research><interventional research><interventional strategy><interventional study><interventions research><ketosis resistant diabetes><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><machine based learning><maturity onset diabetes><medication adherence><medication compliance><member><model-based simulation><models and simulation><multidisciplinary><name><named><naming><novel><older adult><older adulthood><population diversity><programs><promote health equity><racial minority><research and methods><research on health equity><research related to health equity><research to attain health equity><rural individual><scaffold><scaffolding><service availability><service organization><social climate><social context><socioenvironment><socioenvironmental><study design><support network><systems research><telehealth><therapy design><translation><translation research><translational health research><translational health science><translational investigation><treatment access><treatment design><type 2 DM><type II DM><type two diabetes><vulnerable group><vulnerable individual><vulnerable people>