Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Andrew George Gordus · JOHNS HOPKINS UNIVERSITY · 2024 · $43,370 — The Influence of Neuronal States on Perception and Behavior Unlike reflexes, most of our behaviors are governed by internal states such as satiety or arousal that influence how we respond to our environment. The ability to regulate our internal state in response to experience is immediately evident …
B Paige Lawrence · UNIVERSITY OF ROCHESTER · 2024 · $149,463 — Abstract: The overarching goals of the Rochester Environmental Health Sciences Center (EHSC) are to prevent disease and improve health by advancing innovative and impactful translational environmental health research, engaging communities to address environmental health issues, and enhancing career …
J CHRISTOPHER STATES · UNIVERSITY OF LOUISVILLE · 2024 · $21,882 — The University of Louisville’s (UofL) Center for Integrative Environmental Health Science (CIEHS) brings together a multidisciplinary group of investigators working together to develop a framework to understand the complexities of and to integrate the interactions between environmental toxicants, li…
Juan Luis Mendoza · UNIVERSITY OF CHICAGO · 2024 · $72,550 — Project Summary/Abstract Cytokine signaling is essential to the initiation of the immune response against microbial infection and cancer. The immune system is composed of two mechanisms of defense defined as the innate and adaptive immune systems, both of which critically rely on cytokine signaling …
David Allan Drummond · UNIVERSITY OF CHICAGO · 2024 · $120,900 — Project Summary from the Parent Award A conceptual and empirical revolution is occurring in our understanding of the eukaryotic heat-shock response. Heat shock has long been conceived of as a proteotoxic stress, triggering formation of toxic aggregates of denatured proteins, which must be cleaned up…
Katherine Bangen · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2024 · $50,054 — Type 2 diabetes mellitus (T2DM), which is rising in prevalence, increases risk of cognitive impairment and dementia, including Alzheimer's disease (AD). In our prior work we have shown that T2DM is associated with steeper cognitive decline and reduced cerebral blood flow (CBF) in regions that are pr…
Mandar Deepak Muzumdar · YALE UNIVERSITY · 2024 · $183,977 — PROJECT SUMMARY/ABSTRACT Despite significant advances in cancer care, pancreatic ductal adenocarcinoma (PDAC) remains the third leading cause of cancer death in the United States with a 5-year survival rate of ~10%. Obesity and high fat diet (HFD) consumption increase PDAC risk in human cohorts and …
David Artis · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $138,646 — PROJECT SUMMARY Soil-transmitted helminth infections are estimated to infected two billion people worldwide, remaining one of the most neglected groups of infectious diseases and a significant public health and economic challenge. Infected individuals can suffer from malnutrition, growth retardation…
Amy M Cohn · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2024 · $418,859 — PROJECT SUMMARY Social media (SM) has played an increasingly prominent role in adolescents’ daily lives over the past decade, notably coinciding with increased population prevalence of major depressive disorder and eating disorders among adolescents. Correlational research consistently links greater…
Anne Moscona · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $41,396 — Abstract Human parainfluenza viruses (HPIV) cause a significant portion of childhood croup, bronchiolitis and pneumonia in the U.S. and worldwide, yet no effective drugs or vaccines are available. For the lethal Nipah (NiV) and Hendra (HeV) viruses, in the face of human-to-human transmission of NiV,…
MELANIE H. COBB · UNIVERSITY OF PENNSYLVANIA · 2024 · $6,302 — PROJECT SUMMARY (PARENT GRANT) The goals of this proposal are to uncover how pre-mRNA splicing and nuclear speckles are controlled by the kinase TAO2, and to determine why TAO2 is required for successful Influenza virus (IAV) replication. Recent work has identified the understudied protein kinase TA…
DAVID O MELTZER · UNIVERSITY OF CHICAGO · 2024 · $97,554 — PROJECT SUMMARY/ABSTRACT The purpose of the proposed University of Chicago (UChicago) Center for Healthy Aging Behaviors and Longitudinal InvestigationS (CHABLIS) is to promote a sustained research and infrastructure development program that leverages longitudinal data, from both observational and i…
Jennifer Kong · UNIVERSITY OF WASHINGTON · 2024 · $57,849 — PROJECT SUMMARY/ABSTRACT This is a proposal for a Diversity Supplement to fund research training and career development for Dorothy Lartey, a talented undergraduate student and soon postbaccalaureate researcher in the Kong Lab at the University of Washington. The parent grant for this proposal is 4R…
Shashi Kapadia · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $707,647 — PROJECT ABSTRACT: Hepatitis C virus (HCV) during pregnancy predominantly affects people who inject drugs. The rates of perinatal HCV and maternal to child transmission are rising in concert with the current injection drug use crisis. Testing for HCV in the perinatal period has been inadequate, as ha…
Denis Godwin Antoine · JOHNS HOPKINS UNIVERSITY · 2024 · $610,084 — Project Summary This is a competing revision for the Johns Hopkins University (JHU) CFAR to permit continued support for our Diversity, Equity and Inclusion Pathway Initiative (CDEIPI) program, originally funded as a CFAR supplement. The program leverages the strengths of the JHU CFAR and is in line…
MICHAEL L WHITFIELD · DARTMOUTH COLLEGE · 2024 · $1,082,397 — Dysregulation of normal tissue repair processes can lead to fibrosis, a pathological feature of many diseases, including chronic inflammatory conditions, autoimmune diseases, and cancer. Excessive accumulation of extracellular matrix can occur in all tissues, and if progressive, can be fatal. The lo…
Manoj T Duraisingh · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · 2024 · $60,361 — Project Summary/Abstract We confirm that the scope of the parent grant (R01AI168163) will remain unchanged. Malaria parasites infect red blood cells (RBCs), within which they proliferate to cause disease in a continuous cycle of invasion, growth, and egress from one host RBC to another. Free merozoi…
Alan Ross Morrison · OCEAN STATE RESEARCH INSTITUTE, INC. · 2024 · $67,877 — ABSTRACT: Aging and age-related diseases like peripheral artery disease (PAD) lead to considerable morbidity and mortality. Aging is associated with impaired inflammatory arteriogenesis responses to injury. We defined a macrophage signaling axis that activates the mRNA stabilizing protein, HuR, to p…
XIAOFANG WANG · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · 2024 · $346,938 — Project summary/Abstract MSCs play critical roles in tissue turnover and injury healing processes, making them highly valuable in the field of regenerative medicine. The murine teeth present an excellent model for investigating MSC homeostasis due to the rapid turnover and regenerative abilities in …
Paul J Joudrey · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $823,809 — PROJECT SUMMARY Medications for opioid use disorder (MOUD) improve the health of individuals with opioid use disorder (OUD). However, there are significant gaps in obtaining services at each step of the opioid treatment cascade. Individual’s access to MOUD vary by community characteristics, most oft…