Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
HEATHER L TRUE-KROB · WASHINGTON UNIVERSITY · 2024 · $1,208,590 — The mission of the Cell and Molecular Biology (CMB) program at Washington University in St. Louis is to provide rigorous interdisciplinary training to a diverse group of PhD students in four related disciplines in order to prepare them for successful careers in the biomedical workforce. It will prov…
Genevieve Lianne Wojcik · JOHNS HOPKINS UNIVERSITY · 2024 · $466,437 — PROJECT SUMMARY The majority of genomics research is conducted in populations of European descent, leaving other groups behind as we rapidly move from genetic discovery to clinical translation, exacerbating existing health inequities. The transferability of findings is further complicated in admixed…
Elizabeth Selvin · JOHNS HOPKINS UNIVERSITY · 2024 · $589,601 — PROJECT SUMMARY/ABSTRACT: This application is for a five year renewal, years 46‐50, of an institutional training grant in cardiovascular disease epidemiology. The aims of the training program are to develop creative and independent investigators who will contribute to our knowledge of cardiovascular…
Jeffrey M. Rybak · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · 2024 · $83,000 — PROJECT SUMMARY Mucor circinelloides is a Mucoralean mold and a primary causative pathogen of mucormycosis, a severe and life-threatening infection among immunocompromised patient populations. Unfortunately, M. circinelloides possesses a high degree of intrinsic resistance to antifungals, leaving cl…
Akira Nagamori · SALK INSTITUTE FOR BIOLOGICAL STUDIES · 2024 · $32,662 — Project Summary The ability to perform rapid, goal-directed movements accurately and efficiently is critical for interacting with the environment. These movements have provided a key behavioral paradigm for experimental and clinical study, helping to establish theories of sensorimotor control and to…
Yubin Zhou · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · 2024 · $168,026 — Project Summary / Abstract | The overarching goal of this project is to develop targeted therapies for peripheral T cell lymphoma (PTCL), a diverse group of aggressive lymphomas that develop from T cells or natural killer cells and lack standards of care. The current therapeutic options for PTCL are…
MELISSA M HUDSON · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · 2024 · $1,236,790 — Abstract Because many adverse effects of treatment for childhood cancer may not become clinically apparent until the survivor attains maturity or older ages, continued follow-up across the lifespan, from childhood through adulthood, is essential. With the number of childhood cancer survivors in the …
Ivan C Balan · FLORIDA STATE UNIVERSITY · 2024 · $209,449 — Men who have sex with men (MSM) are disproportionally affected by HIV and substance abuse in the U.S., Europe, and Latin America. However, as in the general population, identifying and engaging MSM with problematic substance use (PSU) into treatment is a significant challenge, which results in the g…
Jay T. Rubinstein · UNIVERSITY OF WASHINGTON · 2024 · $538,521 — PROJECT SUMMARY The primary goal of the Research Education Program in the Department of Otolaryngology-Head and Neck Surgery (OtoHNS) at the University of Washington (UW) is to provide every resident in our department with knowledge, skills, and inspiration to establish an independent and sustainab…
Rahul Suresh Shinde · WISTAR INSTITUTE · 2024 · $587,277 — PROJECT SUMMARY The treatment of pancreatic ductal adenocarcinoma (PDAC) remains a major hurdle with 5-year survival of 12%. PDAC resistance to chemotherapy and immunotherapy is thought to arise from the immunosuppressive tumor microenvironment (TME), characterized by a fibrotic stroma and high infi…
Scott H Brewer · FRANKLIN AND MARSHALL COLLEGE · 2024 · $423,133 — PROJECT SUMMARY The long-term objective of this research is to use vibrational reporters and infrared (IR) spectroscopy to study protein and nucleic acid structure and dynamics. A full understanding of these requires a sensitive, site-specific, and relatively non-invasive methodology with sufficien…
Olivia Ifeoma Okereke · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $1,203,241 — PROJECT SUMMARY (OVERALL): The scientific theme of the “MassaChusetts General Hospital ROybal CeNter For BehavIoral Dyadic ResEarch in Alzheimer’s Disease and Related Dementias” (CONFIDE-ADRD) is the development, optimization, testing and implementation of dyadic behavioral prevention interventions …
Mythreye Karthikeyan · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $285,198 — Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. This is a pre-doctoral training grant application for a program in Translational and Molecular Sciences (TMS) at the University of Alabama at Birmingham (UAB). Current…
DAVID B BULLER · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $525,379 — Skin cancer is a significant and expensive public health problem, with ~5 million Americans treated at a cost of over $8 billion annually 29. Melanoma is the deadliest skin cancer, and its incidence has more than tripled in the last four decades 30,31. Indoor tanning (IT) is a well-established cause…
Alessandra Angelucci · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2024 · $424,941 — PROJECT SUMMARY In the mammalian neocortex, inhibitory neurons (INs) profoundly influence cortical computations and dynamics, and their various functions are thought to be mediated by different IN types. While a large diversity of INs exists, molecular markers in mouse cortex identify three major no…
DAVID KRIZAJ · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2024 · $381,250 — PROJECT SUMMARY/ABSTRACT Mechanosensitive ion channels were shown to drive mechanically induced inflammatory signaling in the central and peripheral nervous systems and to exacerbate pathology in neuropathies, skeletal diseases, traumatic brain injury and other neurodegenerative conditions. Suppress…
Roderick Jason Tan · VETERANS HEALTH ADMINISTRATION · 2024 — Chronic kidney disease (CKD) affects over 35 million Americans, and veterans have a higher prevalence of CKD compared to the general population. Progressive CKD leads to end-stage renal disease (ESRD), a state of complete kidney failure requiring dialysis or renal transplantation for survival. Glome…
Debashree Ray · JOHNS HOPKINS UNIVERSITY · 2024 · $204,688 — PROJECT SUMMARY Years of genetic research on various complex human traits have implicated several genetic variants as risk factors for two or more diseases/traits, including seemingly unrelated traits. A recent systematic evaluation of >500 traits from >4100 genome-wide association studies (GWAS) h…
RICHARD A HIRTH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $633,610 — PROJECT SUMMARY The end stage renal disease (ESRD) population on dialysis is a longstanding challenge to manage. This stems from high health care needs, and comorbidities, with mortality rates 10-fold greater than age- matched controls and costs totaling 7% of Medicare’s budget. In contrast to peer …
James J. Daniero · UNIVERSITY OF VIRGINIA · 2024 · $121,125 — Synthetic hydrogels offer a promising platform for volumetric augmentation of the aerodigestive tract for precision medicine approaches. We propose that an ideal biomaterial platform for PPW augmentation to treat VPD would provide a durable tissue bulking effect, maintain implant configuration, and …