Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Philip Murphy · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $15,314 — We have written an Animal Study Proposal that has been approved by the NIAID Animal Care and Use Committee and the SVC. We began research in fall, 2020 after the BSL3 and ABSL3 facilities opened for this purpose. To date, WT and huACE2 transgenic mice on a C57BL/6 background have been infected with…
Leah Katzelnick · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $1,477 — Immunity to endemic coronaviruses and SARS-CoV-2 before and during the COVID-19 pandemic in children in Cebu, Philippines. NIAID and University of the Philippines Manila are collaborating to study SARS-CoV-2 and endemic coronavirus seroprevalence in children in the Central Visayas Region in the Phil…
Yasmine Belkaid · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $3,831,897 — In response to the SARS-CoV-2 pandemic we have made the technologies and platforms at CHI available for characterization of COVID-19 patient samples, as a priority ahead of our ongoing collaborative studies. CHI has contributed to 4 separate studies related to COVID-19 this fiscal year. To address …
Reed Johnson · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $782,853 — Viruses of the Coronaviridae family are enveloped viruses that possess a large (30kb), single-stranded, positive sense, RNA genome that infect a large number of mammals (alpha and beta coronaviruses) and birds (gamma coronaviruses). Four different seasonal coronaviruses (two alpha coronaviruses, 229…
James Inglese · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · 2022 · $450,520 — This project includes the development of biochemical and target-focused assays based on specific protein or nucleic acid targets implicated in disease. The assay designs are considered in the context of analysis and progression strategies for evaluation of a wide range of compound classes using hi…
Eliezer Masliah · NATIONAL INSTITUTE ON AGING · 2022 · $83,630 — The main objective of the Molecular Neuropathology unit (MNU) at Laboratory of Neurogenetics (LNG) is to harness the immune system to better understand the mechanisms of neurodegeneration and to develop therapies for synucleinopathies of the aging population such as DLB, PD and AD. We propose 3 Aims…
BARBARA K FELBER · DIVISION OF BASIC SCIENCES - NCI · 2022 · $563,898 — An ideal HIV vaccine should provide protection against all HIV-1 variants. Thus, an important aspect of HIV vaccine development is the selection of immunogens, which has to take into consideration the diversity of the different HIV clades and the identification of the critical epitope…
TIMOTHY STEDMAN · AMERICAN TYPE CULTURE COLLECTION · 2022 · $3,696,409 — This contract provides unique and quality-assured infectious reagents and resources to the scientific community for use in basic research and product development. The scope of this contract includes the acquisition, authentication, production, preservation, storage, and distribution of research and …
TIMOTHY STEDMAN · AMERICAN TYPE CULTURE COLLECTION · 2022 · $443,137 — This contract provides unique and quality-assured infectious reagents and resources to the scientific community for use in basic research and product development. The scope of this contract includes the acquisition, authentication, production, preservation, storage, and distribution of research and …
BRUCE BLOUGH · RESEARCH TRIANGLE INSTITUTE · 2022 · $97,008 — This task provides for lead identification, development, chemistry and synthesis services under the NIAID Preclinical Services for the Development of Interventional Agents Program.…
JOHN P. KIRWAN · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2022 · $480,869 — Project Summary: Administrative Core The LA CaTS Center Administrative Core has been set up to promote, support, and continually evolve the governance and administrative structure of the Center, to effectively facilitate the necessary leadership, tools and processes required to integrate and align …
SUMIT K CHANDA · SCRIPPS RESEARCH INSTITUTE, THE · 2022 · $2,050,508 — SUMMARY The Administrative Core will coordinate the CAMPP AViDD Center by 1) establishing an organizational structure centered on an Executive Committee responsible for – along with Director, Deputy Directors, and Scientific Advisory Board (SAB) – monitoring overall program progress and making decis…
ANBU DEVASAHAYAM · 2022 · $738,702 — The Clinical Product Center under contract, provides Investigational Product Services for all DAIT-funded and/or sponsored clinical research programs and other NIAID-funded clinical trials as needed. Studies to be supported encompass a broad range of immune-mediated & rare diseases, including: (i) a…
FRED R HIRSCH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2022 · $458,807 — ADMINISTRATIVE CORE: ABSTRACT Our inter-institutional U54 Serological Sciences Center of Excellence (“U54”) Administrative Core provides scientific and administrative oversight for all of the U54’s Projects and Cores. It also provides the main interface with patient advocates, NCI program staff, ex…
DAVID B. WEINER · WISTAR INSTITUTE · 2022 · $275,223 — Project Summary The goal of this Program is to develop a next-generation, universal coronavirus synthetic nucleic acid vaccine employing advancements in nucleic acid delivery of nanoparticles that will provide broad protection against multiple seasonal and emerging CoV. There are seven CoV known to …
Laura F. Gibson · WEST VIRGINIA UNIVERSITY · 2022 · $387,703 — The Technology and Resources for Core Laboratories Core (Technology Core) of the West Virginia Clinical and Translational Science Institute (WVCTSI) supports research infrastructure critical for rapid translation of innovation to positively impact the health of West Virginians. Importantly, the Tech…
SUMIT K CHANDA · SCRIPPS RESEARCH INSTITUTE, THE · 2022 · $67,624,156 — SUMMARY The ongoing COVID-19 pandemic has brought to light an urgent need to enhance the therapeutic preparedness for future viral outbreaks and pandemics. The overarching goal of the “Center for Antiviral Medicines & Pandemic Preparedness” (CAMPP) is thus to develop novel strategies and enhance the…
BRUCE E BOWLER · UNIVERSITY OF MONTANA · 2022 · $60,976 — Project Summary Montana is a geographically large and predominantly rural state with 12 Tribal nations. From the beginning of the SARS-CoV-2 pandemic through the spring of 2021, Montana was severely under-represented in national sequencing databases—and specifically in rural areas—limiting the state…
Christian Bime · UNIVERSITY OF ARIZONA · 2022 · $529,354 — PROJECT SUMMARY The COVID-19 pandemic has dramatically highlighted the serious unmet needs of acute respiratory distress syndrome (ARDS) including the lack of key genetic insights into ARDS susceptibility and health disparities, and the absence of effective FDA-approved pharmacologic interventions t…
Robert Blair · TULANE UNIVERSITY OF LOUISIANA · 2022 · $200,528 — PROJECT SUMMARY Vaping is a serious public health concern that was associated with outbreaks of hospitalizations and deaths in 2019. These outbreaks of electronic vaping associated lung injury (EVALI) coincided with increased use of electronic vaping devices by adolescents and young adults. The rapi…