Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Kristine A. Kuhn · AMERICAN COLLEGE OF RHEUMATOLOGY · 2021 · $54,000 — Project Summary-Abstract The American College of Rheumatology (ACR) has been a leader in the effort to facilitate the bidirectional exchange of cutting-edge scientific information between scientists and investigators in rheumatic diseases through its annual Basic and Clinical Research Conferences. H…
CRISTINA ELIZABETH DAVIS · UNIVERSITY OF CALIFORNIA AT DAVIS · 2021 · $975,463 — Project Summary/Abstract: This proposal has two major goals: 1) Define signature exhaled breath volatile organic compounds (VOCs) to diagnose SARS-CoV-2 infections, and 2) Develop a portable chemical sensing device that can capture and detect exhaled VOCs and includes machine learning algorithms for…
RHONDA C BOYD · CHILDREN'S HOSP OF PHILADELPHIA · 2021 · $270,195 — Depression symptoms in the postpartum period are common and a major public health concern. The 12-month prevalence of postpartum depression (PPD) has been estimated at 9.3% by the National Epidemiologic Survey on Alcohol and Related Conditions. PPD has been shown to interfere not only with individua…
Ivona Vasile Pandrea · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2021 · $391,250 — Abstract With more than 60 million SARS-CoV-2 -infected patients worldwide and nearly 1.5 million COVID-19-related deaths recoreded thus far (November 25), the COVID pandemic is one of the most critical global health problem ever known to humankind, and a major emergency in the US. COVID-19 disprop…
Larry S. Schlesinger · TEXAS BIOMEDICAL RESEARCH INSTITUTE · 2021 · $7,483,557 — OVERALL ABSTRACT The Mission of the Southwest National Primate Research Center (SNPRC) is to improve the health of our global community through innovative biomedical research with nonhuman primates (NHPs). One way that it achieves this goal is by serving as a global resource to scientists that ca…
Robert P. Kimberly · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2021 · $807,056 — ABSTRACT The pandemic prompted by the novel SARS-COV-2 virus continues to have a devastating impact on the health of communities, clinically, socially and economically. Preventive approaches require an understanding of the virus prevalence and the level of herd immunity in the general population. As…
Kelly G Pennell · UNIVERSITY OF KENTUCKY · 2021 · $277,361 — Abstract: Through our NIEHS-SRP research we have advanced materials (membranes to adsorptive and recognition-based polymers) development for degradation and capture/sensing of toxic organics from water. Membranes and polymers-based technologies are also used in air filtration area to remove particle…
Lynn M Yee · NORTHWESTERN UNIVERSITY AT CHICAGO · 2021 · $234,050 — PROJECT SUMMARY Pregnancy is a critical window of opportunity for preventive health interventions, including vaccines. Yet, vaccine hesitancy is a known global phenomenon. Uptake of the currently recommended vaccines in pregnancy (influenza and tetanus, diphtheria, and pertussis [TDaP]) is suboptima…
Michael Cohen-Wolkowiez · DUKE UNIVERSITY · 2021 · $5,500,000 — This supplement will follow the approved Abstract under RADx-UP 3U24-MD016258-01S1. As requested by the NIH, we will deploy the SAY YES! COVID Test pilot in two additional communities likely to experience surges in SARS-CoV-2 infections. These additional communities will not be subject to the sub-st…
Diego G Diel · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · 2021 · $799,280 — The ongoing pandemic of COVID-19 is designated by World Health Organization (WHO) as a Public Health Emergency of International Concern. Similarities among ACE2 receptors predict that there are several animals could function as reservoirs for the virus. Recent studies by us and others identified fel…
Leanne Maree Redman · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2021 · $699,510 — PROJECT SUMMARY The SARS-CoV-2 (COVID-19) pandemic is adversely impacting the physical and mental health of non- pregnant people, including weight gain and increased sedentary behavior, depression, anxiety, and stress. The overarching goal of this administrative supplement to A pragmatic, scalable e…
BRIAN M BARNES · UNIVERSITY OF ALASKA FAIRBANKS · 2021 · $128,440 — Project Summary: To date (3/23/21), Alaska has suffered over 58,000 cases of COVID-19, 1,318 hospitalizations, and 306 deaths. Alaska is a designated Primary Care Health Professional Shortage Area. Likely driven by health disparities, the COVID-19 fatality rate among American Indian/Alaska Native (A…
Soo-Jeong Lee · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2021 · $242,250 — PROJECT SUMMARY/ABSTRACT Disinfectants are widely used in various products and in various settings to prevent infection and transmission of harmful pathogens. Disinfectants, however, contain hazardous chemicals and are known to cause irritation or allergic symptoms in eyes, skin, respiratory and ner…
STEVEN A BENNER · FOUNDATION FOR APPLIED MOLECULAR EVOLUTN · 2021 · $741,716 — Basic Research to Diagnostics and Surveillance in Lower Resource Environments Foundation for Applied Molecular Evolution Steven A. Benner ABSTRACT We will deliver to the NIAID and CDC communities, through basic research, a scientific understanding of pairing, mispairing, and enzymology of natural …
Michael Hannan · PEARL DIAGNOSTICS, INC. · 2021 · $976,576 — Aspergillosis causes morbidity and death in medically immune compromised patients, especially after cancer chemotherapy and transplant. Recently, we have witnessed increased cases of influenza-associated aspergillosis and COVID-19-associated aspergillosis, complicating effective treatment in those c…
Mario Borgnia · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · 2021 · $1,352,100 — The NIEHS Cryo-EM Core continues to lead the deployment and to promote the adoption of techniques in cryo-electron microscopy in the region. Two dozen peer reviewed articles in high impact journals, five in the first half of FY2021, are an attestation of this leadership. One publication, describing …
NICO TJANDRA · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · 2021 · $1,305,351 — We developed a new method to characterize inter-domain motion. We applied this new approach to study the functional flexibility of a three domain modules of factor-H, which is a protein involved in immune signaling against host pathogens. We used residual dipolar coupling (rdc) measured by NMR. The …
Pamela Robey · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · 2021 · $865,069 — During the last fiscal year, the NIH SCCF has made progress in a number of areas as highlighted below. Characterization of RSet nave-like pluripotent stem cells: One of the essential properties of human pluripotent stem cells (hPSCs) is the ground or nave pluripotent state that is primarily establi…
Stephen Leppla · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2021 · $20,392 — The monoclonal S9.6 antibody has the unique property of recognizing DNA/RNA hybrids in a sequence-independent manner. A polyclonal antibody having this specificity is the basis of hybrid capture ELISA-type commercial diagnostic assays for human papilloma virus (HPV) DNA in vaginal swabs. It follows …
Steven Holland · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2021 · $2,687,710 — The major activities of this research project in the past have centered around using our optimized methods and procedures for imaging rhesus macaques, NZW rabbits, and common marmosets on PET/CT scanners while conducting a variety of chemotherapy and basic immunology experiments in Mtb models. We ha…