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Principal Investigator: Leanne Maree Redman
Organization: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
Fiscal Year: 2021
Award: $699,510
Funding agency: National Institute of Nursing Research
PROJECT SUMMARY
The SARS-CoV-2 (COVID-19) pandemic is adversely impacting the physical and mental health of non-
pregnant people, including weight gain and increased sedentary behavior, depression, anxiety, and stress. The
overarching goal of this administrative supplement to A pragmatic, scalable e-health intervention for
management of gestational weight gain in low-income mothers (R01NR017644), is to expand these
observations into pregnant and postpartum populations with the long-term objective of understanding the
impact of the COVID-19 pandemic on perinatal physical and mental health outcomes among women who were
pregnant during the pandemic and to identify mediators of this impact. The central hypothesis is that exposure
to the COVID-19 pandemic during pregnancy will be associated with worsened perinatal physical and mental
health outcomes. The specific aims are: 1) examine the effects of the COVID-19 pandemic on gestational
weight gain among pregnant women in Louisiana, 2) investigate the effects of the COVID-19 pandemic on
racial disparities on adverse pregnancy outcomes among women pregnant during the pandemic in Louisiana,
and 3) examine the effects of the COVID-19 pandemic on perinatal mental health among women pregnant
during the pandemic in Louisiana. Louisiana is a living laboratory for the country and the world, with an
expansive spectrum of income and education levels, and high racial diversity. The specific aims will be tested
with two unique study designs. First, a retrospective chart review of deliveries at Woman's Hospital (Baton
Rouge, Louisiana) will be used to compare gestational weight gain and pregnancy outcomes from women who
were pregnant during the pandemic, compared to women who were pregnant immediately before the
pandemic (n=~23,000); as well as comparing outcomes between Black and White women. Second, using a
sequential explanatory mixed-methods design we will survey and interview two cohorts of recently postpartum
women who were pregnant during the pandemic about their mental health as well as pandemic-related
hardships: Louisiana WIC recipients and patients of Woman's Hospital. The mixed-methods design offers rigor
by integrating components of triangulation, complementarity, expansion, and development. The project survey
includes validated mental health questionnaires and common data elements of the NICHD Promoting Data
Harmonization to Accelerate COVID-19 Pregnancy Research. Potential mediators are pandemic-related
hardships, including isolation and changes to government assistance, housing, employment, or access to
medical care. At the end of the project, our expected outcome is to have quantified the impact of the COVID-19
pandemic on the physical and mental health of pregnant and postpartum women and identified mediators of
that impact.
Terms: <2019 novel corona virus><2019 novel coronavirus><2019-nCoV><Abdominal Delivery><Administrative Supplement><Anxiety><BMI><BMI percentile><BMI z-score><Birth><Black race><Body mass index><C section><COVID crisis><COVID epidemic><COVID pandemic><COVID-19><COVID-19 crisis><COVID-19 epidemic><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 public health crisis><COVID-19 virus><COVID19><COVID19 crisis><COVID19 epidemic><COVID19 global health crisis><COVID19 global pandemic><COVID19 health crisis><COVID19 pandemic><COVID19 public health crisis><COVID19 virus><CV-19><CV19><Caring><Categories><Cesarean><Cesarean section><CoV-2><CoV2><Code><Coding System><Color><Common Data Element><Country><Development><Disasters><Disease><Disorder><Economic Income><Economical Income><Economics><Education Level><Educational Background><Employment><Exposure to><Future><Gestation><Gestational Diabetes><Gestational Diabetes Mellitus><Goals><Government><Guidelines><Health Insurance><Hospitals><Housing><Incidence><Income><Individual><Insurance><Intervention><Intervention Strategies><Interview><Laboratories><Louisiana><Low income><Mediating><Mediator><Mediator of Activation><Mediator of activation protein><Medicaid><Medical><Medical Records><Mental Depression><Mental Health><Mental Hygiene><Methods><Mothers><NICHD><National Institute of Child Health and Human Development><National Institute of Children's Health and Human Development><Neighborhoods><Obesity><Outcome><Over weight><Overweight><Parturition><Patients><Perinatal><Peripartum><Population><Position><Positioning Attribute><Post-partum Women><Postpartum><Postpartum Period><Postpartum Women><Pregnancy><Pregnancy Outcome><Pregnancy-Induced Diabetes><Pregnant Women><Preventative strategy><Prevention strategy><Preventive strategy><Privatization><Psychological Health><Public Health><Questionnaires><Quetelet index><Race><Racial Group><Racial Segregation><Racial Stocks><Reporting><Research><Research Design><Risk><Risk Factors><SARS corona virus 2><SARS-CoV-2><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-CoV2><SARS-CoV2 epidemic><SARS-CoV2 pandemic><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Sedentary behavior><Sedentary life-style><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe acute respiratory syndrome related corona virus 2><Special Supplemental Nutrition Program for Women, Infants, and Children><Stress><Structure><Study Type><Survey Instrument><Surveys><Testing><Time><Underweight><WIC><WIC program><Weight Gain><Weight Increase><Woman><Women, Infants and Children (WIC)><Wuhan coronavirus><adiposity><adverse pregnancy outcome><black female><black women><body weight gain><body weight increase><cohort><corona virus disease 2019><corona virus disease 2019 epidemic><corona virus disease 2019 pandemic><coronavirus disease 2019><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease 2019 virus><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><corpulence><data harmonization><depression><design><designing><developmental><disparities in race><disparity in health><e-Health><eHealth><education access><expectant mother><expecting mother><gestational weight gain><hCoV19><harmonized data><health disparity><health insurance plan><improved><interventional strategy><low SES><low socio-economic position><low socio-economic status><low socioeconomic position><low socioeconomic status><nCoV2><pandemic><pandemic disease><perinatal health><perinatal mental health><perinatal outcomes><physical conditioning><physical health><post-partum><pregnancy diabetes><pregnancy disorder><pregnant><pregnant mothers><psychosocial><race disparity><racial disparity><racial diversity><racially diverse><recruit><sedentary lifestyle><segregation><service delivery><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social health determinants><study design><wt gain>