COVID 06 Taylor 508

CDC ACIP — Vaccine Advisory Committee

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National Center for Immunization & Respiratory Diseases
Trends in COVID -19-Associated Hospitalizations —COVID -19-Associated 
Hospitalization Surveillance Network (COVID -NET), March 2020–February 2023
Christopher A. Taylor, PhD
Epidemiologist, COVID -NET
Coronaviruses and Other Respiratory Viruses Division
National Center for Immunizations and Respiratory DiseasesCenters for Disease Control and Prevention
Advisory Committee on Immunization Practices
February 24, 2023

Weekly Population-Based Rates of COVID -19-Associated Hospitalizations 
among All Ages —COVID -NET, March 2020 –February 2023
020406080100120140
3/7/2020
4/7/2020
5/7/2020
6/7/2020
7/7/2020
8/7/20209/7/2020
10/7/202011/7/2020
12/7/2020
1/7/2021
2/7/2021
3/7/2021
4/7/2021
5/7/2021
6/7/2021
7/7/2021
8/7/20219/7/2021
10/7/202111/7/2021
12/7/2021
1/7/2022
2/7/2022
3/7/2022
4/7/2022
5/7/2022
6/7/2022
7/7/2022
8/7/20229/7/2022
10/7/202211/7/2022
12/7/2022
1/7/2023Rate per 100,000 population
Week Ending Date
≤17 years 18–49 years 50–64 years 65–74 years ≥75 years
Gray boxes indicate potential reporting delays. Interpretation of trends should be excluded from these weeks. 2
Weekly Population-Based Rates of COVID -19-Associated Hospitalizations 
among Adults Ages ≥18 Years — COVID -NET, March 2020 –February 2023
020406080100120140Rate per 100,000 population
Week Ending DateMarch 2020 –February 2023 (entire pandemic period)
18–49 years 50–64 years 65–74 years ≥75 years020406080100120140Rate per 100,000 population
Week Ending DateAugust 2022– February 2023
Gray boxes indicate potential reporting delays. Interpretation of trends should be excluded from these weeks. 3
Weekly Population -Based Rates of COVID -19-Associated Hospitalizations among 
Children and Adolescents Ages ≤17 Years —COVID- NET, March 2020 –February 2023
0102030405060708090Rate per 100,000 population
Week Ending DateAugust 2022– February 2023
0102030405060708090Rate per 100,000 population
Week Ending DateMarch 2020 –February 2023 (entire pandemic period)
<6 months 6 months–<2 years 2–4 years 5–11 years 12–17 years
Gray boxes indicate potential reporting delays. Interpretation of trends should be excluded from these weeks. 4
Weekly Proportions of COVID-19-Associated Hospitalizations by 
Adult Age Group — COVID-NET, March 2020 –February 2023
0%10%20%30%40%50%60%70%80%90%100%
3/7/2020
4/11/2020
5/16/2020
6/20/2020
7/25/2020
8/29/202010/3/202011/7/2020
12/12/2020
1/16/20212/20/20213/27/2021
5/1/20216/5/2021
7/10/20218/14/20219/18/2021
10/23/2021
11/27/2021
1/1/20222/5/2022
3/12/20224/16/20225/21/20226/25/20227/30/2022
9/3/2022
10/8/2022
11/12/2022
12/17/2022
1/21/2023March 2020 –February 2023 (entire pandemic period)
18–49 years 50–64 years 65–74 years ≥75 years0%10%20%30%40%50%60%70%80%90%100%
8/6/2022
8/20/2022
9/3/2022
9/17/2022
10/1/2022
10/15/2022
10/29/2022
11/12/2022
11/26/2022
12/10/2022
12/24/2022
1/7/2023
1/21/2023
2/4/2023August 2022– February 2023
40% of hospitalizations are
in adults ages ≥75 years .
5
Weekly Proportions of COVID-19-Associated Hospitalizations by 
Pediatric Age Group — COVID-NET, March 2020 –February 2023
0%10%20%30%40%50%60%70%80%90%100%
3/7/2020
4/11/2020
5/16/2020
6/20/2020
7/25/2020
8/29/2020
10/3/2020
11/7/2020
12/12/2020
1/16/2021
2/20/2021
3/27/2021
5/1/2021
6/5/2021
7/10/2021
8/14/2021
9/18/2021
10/23/2021
11/27/2021
1/1/20222/5/2022
3/12/2022
4/16/2022
5/21/2022
6/25/2022
7/30/2022
9/3/2022
10/8/2022
11/12/2022
12/17/2022
1/21/2023March 2020 –February 2023 (entire pandemic period)
<6 months 6 months –<2 years 2–4 years 5–11 years 12–17 years0%10%20%30%40%50%60%70%80%90%100%
8/6/2022
8/20/2022
9/3/2022
9/17/2022
10/1/2022
10/15/2022
10/29/2022
11/12/2022
11/26/2022
12/10/2022
12/24/2022
1/7/2023
1/21/2023
2/4/2023August 2022– February 2023
6
Proportions of COVID- 19-Associated Hospitalizations with COVID -19 as a Likely Reason for 
Admission by Age and Variant Predominance Period —COVID -NET, June 2020– November 2022
0102030405060708090100
Total 0–4 years 5–11 years 12–17 years 18–49 years 50–64 years ≥65 yearsWeight % of hospitalizations
Period of variant predominance
Pre-Delta (6/1/20–6/19/21)
Delta (6/20–12/18/21)
Omicron BA.1 (12/19/21–3/19/22)
Omicron BA.2 (3/20–6/18/22)
Omicron BA.5 and later (6/19 –11/30/2022)•Many children ages 
≤4 years and adults 
ages ≥50 years are 
still admitted for 
COVID.
•Adolescents and younger adults ( ages 
12–49 years ) are 
less likely to be 
admitted for COVID .
7
Underlying Medical Conditions among Non -Pregnant Adults 
Ages ≥18 Years — COVID-NET, June–November 2022
68.6
54.6
35.032.5 30.7
24.6
17.514.9
9.75.3
01020304050607080Weighted % of hospitalizations
Data are limited to hospitalizations where COVID -19 is a likely primary reason for admission.96% of hospitalized adults have
≥1 underlying medical condition .
8
Underlying Medical Conditions among Children and Adolescents 
Ages ≤17 Years — COVID-NET, June– November 2022
13.1
11.2
8.8 8.8
7.9
6.7 6.6 6.4
5.3
3.5 3.4
2.62.2
02468101214Weighted % of hospitalizations
Data are limited to hospitalizations where COVID -19 is a likely primary reason for admission.49% of hospitalized children and 
adolescents have no underlying 
medical conditions .
9
Underlying Medical Conditions among Children and 
Adolescents by Age Group —COVID-NET, June– November 2022
051015202530
<2 years 2–4 years 5–11 years 12–17 yearsWeighted % of hospitalizations
Asthma Prematurity Feeding tube dependence
Obesity Chronic lung disease, not including asthma Immunocompromising condition
Gastrointenstinal/liver Disease Blood disorders Chronic lung disease of prematurity
Autoimmune/inflammatory disease Abnormality of airway Diabetes
Data are limited to hospitalizations where COVID -19 is a likely primary reason for admission.10
Vaccination Status by Age Group among Non -Pregnant Adults 
Ages ≥18 Years —COVID-NET, October– November 2022
Data are limited to hospitalizations where COVID -19 is a likely primary reason for admission. Unvaccinated: No recorded doses of COVID -19 vaccine. Vaccinated, but no bivalent booster: 
Completed a primary series with or without ≥1 booster dose but did not receive an updated bivalent booster dose. Updated bivalent booster : Received updated bivalent booster dose. Partially 
vaccinated : Received at least one dose of COVID -19 but was not considered fully vaccinated at the time of a positive SARS -CoV-2 test. Pers ons with unknown vaccination status are excluded. 58.250.4
34.1
23.115.0 12.540.3
42.4
58.0
66.9 79.676.55.42.73.42.78.0
0%10%20%30%40%50%60%70%80%90%100%
5–11 years 12–17 years 18–49 years 50–64 years 65–74 years ≥75 yearsPercent of hospitalizations
Unvaccinated Vaccinated, but no bivalent booster Updated bivalent booster Partially vaccinated
11
Monthly Age-Adjusted Rates of Lab- Confirmed Hospitalizations by Vaccination Status 
among Adults Ages ≥18 Years —COVID- NET, January 2021–December 2022
0100200300400500600700Rate per 100,000 population
Month of Admission
Unvaccinated Primary series Primary series & ≥1 booster
Primary series & ≥2 boosters Vaccinated, no bivalent booster Updated bivalent booster
Data are based on all hospitalizations regardless of reason for admission. Unvaccinated : No recorded doses of COVID -19 vaccine. Primary series ± ≥1 booster: Completed a primary series with or without ≥1 
booster dose but did not receive an updated bivalent booster dose. Vaccinated, but no bivalent booster : Completed a primary series with or without ≥1 booster dose but did not receive an updated bivalent 
booster dose. Updated bivalent booster : Received updated bivalent booster dose. Persons with partial or unknown vaccination status are excluded. See https://covid.cdc.gov/covid-data-tracker/#covidnet -
hospitalizations-vaccination for complete definitions of vaccination categories. In December 2022, compared to adults 
who received an updated bivalent booster dose, the monthly rates of hospitalization were-16x higher among unvaccinated and 
-2.6x higher in vaccinated adults without an updated booster dose.
12
Acknowledgments
Coronaviruses and Other Respiratory 
Viruses Division (CORVD) (proposed):
RESP-NET Team (COVID -NET/RSV -NET):
•Fiona Havers
•Huong Pham
•Michael Whitaker
•Kadam Patel
•Jenny M ilucky
•Onika Anglin
•Bhoomija C hatwani
Many others in CORVD….State, Local, and Territorial h
ealth Department partners
RESP- N ET partners
Thank you.

For more information, contact CDC
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TTY:  1 -888-232-6348    www.cdc.gov
T
he findings and conclusions in this report are those of the authors and do not necessarily represent the 
official position of the Centers for Disease Control and Prevention.