Document text
Principal Investigator: Julie Elaine Miller
Organization: NEW ENGLAND RESEARCH INSTITUTES, INC.
Fiscal Year: 2020
Award: $4,327,649
Funding agency: National Heart Lung and Blood Institute
PROJECT SUMMARY/ABSTRACT
To address the knowledge gap discussed previously, NIH is initiating a national research program focused on
pediatric SARS-CoV-2, COVID-19 and MIS-C. This goal of the program is to gain comprehensive
understanding of phenotype, natural history, outcomes, and pathobiology of MIS-C. The Program will have
several components including a MIS-C Cohort Study, adaptive design trials, long-term follow-up and a robust
cloud-based data platform. The PHN DCC will serve to coordinate some of the components of the Program.
The Specific Aims of the DCC are as follows:
AIM 1: MANAGE CORE PROGRAM OPERATIONS
AIM 2: MANAGE MIS-C COHORT STUDY DEVELOPMENT, LAUNCH, AND DISSEMINATION OF
RESULTS
AIM 3: PROVIDE SUPPORT SERVICES TO PROGRAM COMPONENTS
Terms: <2019 novel coronavirus><2019-nCoV><Address><Agreement><Budgets><COVID-19><COVID19><Childhood><Clinical Trials Data Monitoring Committees><Cohort Studies><Concurrent Studies><Cyclicity><Data><Data Coordinating Center><Data Coordination Center><Data Monitoring Committees><Data and Safety Monitoring Boards><Development><ECG><EKG><Electrocardiogram><Electrocardiography><Goals><Heart><Individual><Information Dissemination><Infrastructure><Knowledge><Laboratories><Leadership><Link><Logistics><Long-term Follow-up><Longterm Follow-up><MR Imaging><MR Tomography><MRI><Magnetic Resonance Imaging><Maintenance><Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance><Methods><Monitor><NHLBI><NIH><NMR Imaging><NMR Tomography><National Heart, Lung, and Blood Institute><National Institutes of Health><Natural History><Nuclear Magnetic Resonance Imaging><Outcome><Participant><Periodicity><Phenotype><Progress Reports><Protocol><Protocols documentation><Research><Review Committee><Rhythmicity><Running><SARS-CoV-2><SARS-CoV2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related coronavirus 2><Safety Monitoring Boards><Services><Severe acute respiratory syndrome coronavirus 2><Site><System><TimeLine><United States National Institutes of Health><Update><Work><Wuhan coronavirus><Zeugmatography><cloud based><conference><convention><corona virus disease 2019><coronavirus disease 2019><data integration><developmental><dissemination of results><electronic data capture system><insurance claims><long-term followup><longterm followup><operation><payment><pediatric><programs><recruit><social media><summit><symposia><symposium><trial design><web site><webinar><website>