Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
JAMES C MULLIKIN · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · 2022 · $10,295,725 — Over the last year, NISC operated the following suite of production sequencing machines: 1 PacBio Sequel 2, 1 NovaSeq 6000, 1 Oxford Nanopore GridION, 1 Oxford Nanopore PromethION, and 3 MiSeqs. Using these platforms, we have generated over 3,259 billion reads in the past year. Though we remain cons…
Ighovwerha Ofotokun · EMORY UNIVERSITY · 2022 · $1,186,474 — PROJECT SUMMARY/ABSTRACT The Clinical Research Core (CRC) (Core D) provides services to support researchers conducting human subjects research studies investigating the pathogenesis of HIV disease, treatment and prevention of HIV, strategies to eliminate HIV from those who are infected, and the redu…
Daniel E Voth · UNIV OF ARKANSAS FOR MED SCIS · 2022 · $228,000 — PROJECT SUMMARY/ABSTRACT A primary means of research support for investigators in the Center for Microbial Pathogenesis and Host Inflammatory Responses (CMPHIR) in Phase III will be the NIGMS-funded Pilot Grant Program (PGP), supplemented with institutional funds ($100,000 per year for each year) t…
Olivier Elemento · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · 2022 · $147,304 — Data Management Core Principal Investigator: Olivier Elemento, PhD. Co-I: Zhengming Chen, PhD Abstract This Core will provide bioinformatics expertise and support with data integration and analyses. The Core will serve three main goals. First, it will provide central data storage and data management…
John Damon Chodera · SLOAN-KETTERING INST CAN RESEARCH · 2022 · $7,107,143 — PROJECT SUMMARY / ABSTRACT - Administrative Core The AI-driven Structure-enabled Antiviral Platform (ASAP) AViDD Center is organized as a distributed antiviral discovery effort that will produce---in addition to three Investigational New Drug (IND) applications---a robust pipeline of open science da…
Reuben S Harris · UNIVERSITY OF MINNESOTA · 2022 · $7,505,644 — Core A – Administration ABSTRACT The primary goals of Core A – Administration are to provide leadership, logistical support, and coordinated communication for all members and collaborators of the Midwest AViDD Center in order to expedite the successful completion of all specific aims. The PI of Cor…
John Damon Chodera · SLOAN-KETTERING INST CAN RESEARCH · 2022 · $6,599,276 — SARS-CoV-2 continues to cause severe morbidity and mortality in the current pandemic and future RNA virus pandemics are inevitable. Clinical-trial-ready antivirals are lacking for all RNA viruses of pandemic potential. It is imperative that the world have access to an arsenal of compounds ready to b…
PETER MYLER · SEATTLE CHILDREN'S HOSPITAL · 2022 · $386,529 — To apply state-of-the-art, high-throughput structural biology technologies to experimentally characterize the three-dimensional atomic structure of targeted proteins on the NIAID Category A-C priority pathogens list and organisms causing emerging and re-emerging infectious diseases. This program als…
ETHAN DMITROVSKY · LEIDOS BIOMEDICAL RESEARCH, INC. · 2022 · $57,909,079 — The purpose of the National Cancer Institute’s SARS-CoV-2 Serological Sciences Network (SeroNet) is to study the immune response to COVID-19 by developing and deploying serological assays of the highest specificity and sensitivity, expanding the national testing capacity for SARS-CoV-2 antibodies, a…
TIMOTHY STEDMAN · AMERICAN TYPE CULTURE COLLECTION · 2022 · $2,924,707 — This contract provides unique and quality-assured infectious reagents and resources to the scientific community for use in basic research and product development. The scope of this contract includes the acquisition, authentication, production, preservation, storage, and distribution of research and …
Jean-Laurent Casanova · ROCKEFELLER UNIVERSITY · 2022 · $74,534 — Project Summary In December 2019, a novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, China, and quickly spread worldwide, with an increasing number of cases and deaths. In populations naive to this new pathogen, there has been immense inter-individual clinical variability among infected …
DEBORAH S HASIN · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · 2022 · $255,746 — Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2 is a global pandemic. While most COVID-19 cases are mild or moderate, severe cases (~15%) require hospitalization, critical cases (~5%) require intensive care, and many deaths occur. Males, Blacks and Hispanics are at greater risk for COVID-19…
John Damon Chodera · SLOAN-KETTERING INST CAN RESEARCH · 2022 · $67,673,902 — PROJECT SUMMARY/ABSTRACT - Overall SARS-CoV-2 continues to cause severe morbidity and mortality in the ongoing pandemic. Future RNA virus epidemics and pandemics are inevitable. New clinical-trial-ready antivirals are urgently needed RNA viruses of pandemic potential. COVID-19 has further underscore…
Reuben S Harris · UNIVERSITY OF MINNESOTA · 2022 · $66,431,207 — Overall – Midwest AViDD Center ABSTRACT The Midwest Anti-Viral Drug Development (AViDD) Center was formalized as a direct response to NIAID U19 RFA RFA-AI-21-050 “Emergency Awards: AViDD Centers for Pathogens of Pandemic Concern”. The Co- PIs of the Midwest AViDD Center are Reuben Harris and Fang L…
Matthew Rizzo · UNIVERSITY OF NEBRASKA MEDICAL CENTER · 2022 · $60,285 — Project Summary: This application from the Great Plains IDeA Clinical and Translational Research (GP IDeA-CTR) network responds to NIGMS call (NOT-GM-22-026) for Urgent Competitive Revisions to IDeA Programs for SARS-CoV-2 Surveillance Studies. Our innovative approach addresses three specific aims (…
Mohamed Abdel Mohsen · RUSH UNIVERSITY MEDICAL CENTER · 2022 · $208,746 — PROJECT SUMMARY Recent data show that 10-30% of coronavirus disease 2019 (COVID-19) patients do not fully recover and suffer from a wide range of symptoms that persist after the SARS-CoV-2 infection has been cleared (so-called post- COVID-19 syndrome or Long Hauler). Severe COVID-19 and associated r…
Catherine A. Gao · NORTHWESTERN UNIVERSITY AT CHICAGO · 2022 · $85,550 — A. Project Summary and Abstract The goals of this NRSA postdoctoral fellowship proposal are: 1) to facilitate Dr. Catherine Gao’s development as an independent physician-scientist and an expert in the handling, integration, and computational analyses of complex datasets, and 2) to model transitions …
Christian L. Lorson · UNIVERSITY OF MISSOURI-COLUMBIA · 2022 · $2,340,729 — The objective of the parent G20 grant is to provide state of the art, highly safe and secure biocontainment facilities and services to faculty, student and staff researchers at the MU Laboratory for Infectious Diseases, one of 12 NIH/NIAID Regional Biocontainment Laboratories. The LIDR/MURBL is c…
Alexander Viloria Winnett · CALIFORNIA INSTITUTE OF TECHNOLOGY · 2022 · $51,752 — PROJECT SUMMARY Morbidity and mortality in COVID-19 is the result of an exaggerated inflammatory response causing severe tissue and organ damage. However, the biological mechanism for why some individuals progress from initially stable to ultimately critical condition has not been fully elucidated. …
JUDITH FEINBERG · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2022 · $156,195 — Project Summary/Abstract The COVID-19 pandemic caused by SARS-CoV-2 has resulted in social distancing measures, the total consequences of which, particularly as they relate to substance use and drug overdose deaths, are unknown. News reports and early studies have suggested increases in opioid overd…