Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
ROB S MCCONNELL · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $1,643,495 — OVERALL: PROJECT SUMMARY/ABSTRACT The mission of the Southern California Environmental Health Sciences Center (SCEHSC) is to develop the scientific knowledge base, investigator teams, and community engagement needed to reduce the burden of diseases and disability from environmental impacts. The SCEH…
Gary A Piazza · AUGUSTA UNIVERSITY · 2024 · $410,108 — Project summary/abstract Nonsteroidal anti-inflammatory drugs (NSAIDs) have cancer chemopreventive activity, but are not recommended for long-term use because of toxicities resulting from cyclooxygenase (COX) inhibition. However, sulindac and its congener, indomethacin (indo) inhibit the growth and …
PAUL KHAVARI · STANFORD UNIVERSITY · 2024 · $319,844 — This competing renewal of the Postgraduate Training Program in Epithelial Biology, AR07422, aims to extend 40 continuous years of NIH-supported postdoctoral training in skin research at Stanford. The program objective is to train postdoctoral fellows for future careers in research relevant to skin d…
Vanessa Cerda · VANDERBILT UNIVERSITY · 2024 · $89,775 — PROJECT SUMMARY In the United States, English is the primary language of instruction and testing in most schools. However, many bilingual students entering US schools learned foundational concepts in a language other than English and might be at a developmental disadvantage when expected to build on…
LAURA J ESSERMAN · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $1,741,554 — PROJECT SUMMARY/ABSTRACT The WISDOM Study (Women Informed to Screen Depending on Measures of risk) is a pragmatic trial comparing a personalized approach to breast cancer screening – in which the intensity and modality of screening is dependent upon stratified personal risk -- against the gold stand…
SEEMA BHATNAGAR · CHILDREN'S HOSP OF PHILADELPHIA · 2024 · $220,000 — PROJECT SUMMARY Traumatic brain injuries (TBI) have devastating consequences for the quality of life of affected individuals. Mild TBI (mTBI) is extremely common affecting approximately 42 million individuals worldwide (NINDS.gov; 2015). Key symptoms include excessive daytime sleepiness, poor memory…
Joseph Michael DeGutis · BOSTON VA RESEARCH INSTITUTE, INC. · 2024 · $403,224 — The goal of this proposal is to better characterize the cognitive and neural basis of face perception heterogeneity in developmental prosopagnosia (DP) and to test whether potential perceptual subtypes are better suited for one type of cognitive training program vs. another. This is relevant to the …
Lisa Zubkoff · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $545,008 — Project Summary The American Society of Clinical Oncology (ASCO) recommends “…combined standard oncology care and palliative care…early in the course of illness for any patient with metastatic cancer and/or high symptom burden”. Unfortunately, early palliative care is not routinely incorporated…
Rachelle L Crescenzi · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $498,183 — The overall goal of this work is to address clinical unmet needs for patients with lipedema using advanced magnetic resonance imaging (MRI) methods of vascular and molecular dysfunction, in sequence with portable clinical measures of adiposity and edema. Specifically, lipedema is a disease marked by…
Nickhill Hitesh Bhakta · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · 2024 · $98,612 — PROJECT SUMMARY/ABSTRACT Background: Multimorbidity, defined as the co-occurrence of two or more physical or mental chronic illnesses, is prevalent and rising globally. New measures of multimorbidity that provide unique insights into the spectrum, pattern and magnitude of multiple co-morbid conditio…
Mingming Wu · CORNELL UNIVERSITY · 2024 · $351,339 — Project Summary Cancer metastasis accounts for over 90% of all cancer deaths. Important abilities of metastatic tumor cells include breaking away from the primary tumor and invading into surrounding tissue before disseminating to secondary tumor sites. Solid tumor stress caused by rapid growth of tu…
Sara Tartof · KAISER FOUNDATION RESEARCH INSTITUTE · 2024 · $760,514 — SUMMARY/ABSTRACT In 2015, tuberculosis (TB) surpassed HIV as the number one cause of infectious disease deaths worldwide. In the U.S., California has the highest incidence and largest number of TB cases in the nation, comprising nearly one-quarter of all new active TB cases in 2017. More than 80% of…
Philipp Gutruf · UNIVERSITY OF ARIZONA · 2024 · $428,357 — Project Summary Osteopenic fragility fractures are a devastating result of poor bone quality secondary to high mortality and long- term patient disability. Currently there is limited understanding on the mechanistic level reflected in the relatively few available treatment and diagnostic options. Du…
Ryan Lee Minster · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $1,466,436 — SUMMARY/ABSTRACT Title: Lipidomics and structural genomics of cardiometabolic health in Samoan adults Project Period: 09/01/2023–08/31/2027 Pacific Islanders, such as Samoans, are disproportionally burdened by cardiometabolic disease yet are un- derrepresented as participants in health research gene…
Adetunji T Toriola · WASHINGTON UNIVERSITY · 2024 · $569,887 — ABSTRACT Women with dense breasts on mammogram have a 4-6-fold increased risk of breast cancer. A sizeable proportion of premenopausal breast cancer cases (29%) are attributable to having dense breasts. Observational and clinical trial data have shown that a decrease in breast density translates to …
William T. SULLIVAN · UNIVERSITY OF CALIFORNIA SANTA CRUZ · 2024 · $375,913 — The goal of this proposal is to elucidate the molecular and cellular basis of a newly discovered diverse set of adaptive mechanisms that maintain the integrity of the genome during anaphase and telophase. Eukaryotic cells have evolved sophisticated mechanisms to maintain genomic integrity. In respon…
Dobromir Rahnev · GEORGIA INSTITUTE OF TECHNOLOGY · 2024 · $369,995 — Project Summary. Metacognition is the ability to reflect on and evaluate one’s behavior. Impaired metacognition has been proposed as a major symptom for a number of psychiatric disorders such as schizophrenia, depression, generalized anxiety disorder, obsessive-compulsive disorder, and even substanc…
Eimear Elizabeth Kenny · UNIVERSITY OF PENNSYLVANIA · 2024 · $938,104 — Polygenic risk scores (PRS), that aggregate risk across common variants in the genome, have emerged as a powerful tool towards implementing genomic medicine. Unfortunately, the vast majority of genomic data from which current PRS are estimated is coming only from European ancestry individuals thus p…
Lora Anne Cavuoto · STATE UNIVERSITY OF NEW YORK AT BUFFALO · 2024 · $149,780 — Project Summary The University at Buffalo (UB), SUNY Occupational Safety and Health (OSH) Training Program prepares MS degree graduates who go on to affect OSH practice in New York State and the surrounding region. Specific objectives of the program include: 1) to provide a high-quality, comprehensi…
Brian Chih-Seng Searle · MAYO CLINIC ROCHESTER · 2024 · $174,847 — PROJECT SUMMARY The genomic difference between individuals is estimated to be approximately 0.5% of base pairs, but this small diversity can drastically affect the interpretation of both genome- and downstream proteome-level data. While most germline variants between individuals are neutral, there a…