Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Jessica Cardenas · UNIVERSITY OF COLORADO DENVER · 2024 · $390,000 — Complications that arise secondary to an exaggerated innate immune response, such as multiple organ failure, are a major cause of late-stage mortality in trauma patients. My overall goal is to initiate an innovative and translational research program focused on elucidating mechanisms through which t…
JULIE ANN SOSA · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $669,355 — Abstract Addressing Surgical Disparities at the Root: Improving Diversity in the Surgical Workforce The recent COVID-19 pandemic, racially motivated murders, and subsequent protests underscore what we already know--that racial disparities in medicine run far deeper than patient outcomes alone and mu…
ALISA B BUSCH · HARVARD MEDICAL SCHOOL · 2024 · $749,529 — PROJECT SUMMARY While alcohol use disorder (AUD) is a leading cause of morbidity and mortality, and efficacious medication and behavioral treatments exist, only a small minority with AUD in the US receive any AUD treatment. Additionally, there are substantial disparities in receiving AUD care across…
Peter F Rebeiro · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $371,875 — Project Summary / Abstract The HIV, HCV, and opioid epidemics disparately impact populations in different regions of the US, with higher burden (51% of new HIV diagnoses in the US) and poorer outcomes (highest HIV mortality in the US, at 6-10 per 1,000 persons with HIV) in the South, particularly l…
Joel D Mainland · MONELL CHEMICAL SENSES CENTER · 2024 · $204,557 — PROJECT SUMMARY Only about 4% of biomedical scientists at US research institutions and universities are from underrepresented (UR) groups, even though these groups make up 33% of the US population. To support diversification of the biomedical workforce, with particular focus on the field of the chem…
Mary Kathryn Irvine · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · 2024 · $592,950 — Abstract The Ryan White HIV/AIDS Program (RWHAP) for low-income people with HIV (PWH) is a key resource for reducing HIV health disparities and scaling up evidence-based interventions. As RWHAP serves >50% of US PWH, RWHAP outcomes are vital to achieving “getting to zero”/ Ending the HIV Epidemic (…
Joshua Adam Barocas · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2024 · $619,921 — ABSTRACT People who inject drugs (PWID) remain a high priority population under the Ending the HIV Epidemic: Plan for America (EHE) with 11% of new HIV infections attributable to injection drug use (IDU). IDU has led to multiple recent outbreaks of HIV in the US, driven primarily by the ongoing opio…
PAUL Anthony WENDER · STANFORD UNIVERSITY · 2024 · $409,237 — Project Summary/Abstract: This renewal involves integrated and interdependent synthetic, mechanistic, structural, biochemical mode of action, computer modeling, collaborative and preclinical studies directed at the design, synthesis, assay and advancement of fundamentally new and unique therapeutic …
Danielle Elise Rose · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · 2024 — Background: [With the onset of the COVID-19 pandemic, VA primary care (PC) experienced a substantial increase in video-based encounters, nationwide. This rapid uptake of video-based care in PC clinics, however, varied by site. Given that the VA is committed to continue expanding VA Video Connect (VV…
Eric Jutkowitz · PROVIDENCE VA MEDICAL CENTER · 2024 — Background: The US Department of Housing and Urban Development-Veterans Affairs Supportive Housing (HUD-VASH) program offers permanent, subsidized independent housing and case management to over 60,000 Veterans annually. In response to COVID-19, HUD-VASH shifted case management from in-person to tel…
Sarah Emily Snider · BEAM DIAGNOSTICS, INC. · 2024 · $935,721 — PROJECT SUMMARY Opioid use disorder (OUD) is a major contributor to excessive disability, morbidity, and mortality in the United States. Currently, almost 10 million Americans misuse opioid substances and 2.7 million Americans suffer from OUD. In the past year alone, U.S. opioid overdose deaths have…
Tierra Smiley Evans · UNIVERSITY OF CALIFORNIA AT DAVIS · 2024 · $214,874 — PROJECT SUMMARY Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern pose a global challenge to the effectiveness of existing and future vaccines. This project will address questions surrounding the immunological response to different sarbecovirus exposure patter…
Rachel C Shelton · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $542,964 — Project Summary Widespread implementation, scale-up, and sustainability of culturally-appropriate, evidence-based programs is critical to reducing the significant and disproportionate burden of cancer among Black women. Community- engaged Lay Health Advisor (LHA) programs are highly successful in re…
NINA T GENTILE · TEMPLE UNIV OF THE COMMONWEALTH · 2024 · $383,128 — The Temple-led Emergency care research network (Temple-SIREN) is comprised of multiple community and academic medical centers and EMS providers throughout Philadelphia, New Jersey, Delaware, and Maryland to execute SIREN emergency care trials. To meet the needs for specific study enrollment, Temple-…
Andrew Horn · KANSAS STATE UNIVERSITY · 2024 · $36,760 — PROJECT SUMMARY Heart disease is the leading cause of death in the United States. Diaphragm dysfunction is prevalent in heart failure (HF) patients and both precedes and surpasses that seen in other locomotory skeletal muscles; increasing susceptibility to respiratory muscle failure and exercise in…
JILL Allison HOLLENBACH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $449,783 — PROJECT SUMMARY The Human Leukocyte Antigen (HLA) region on human chromosome 6p21 is the most medically important region of the human genome. Over 100 infectious, autoimmune and pharmacological disease phenotypes and cancers are associated with genetic variation of HLA, and matching of HLA genotypes…
Angela R Dixon · EMORY UNIVERSITY · 2024 · $132,057 — PROJECT SUMMARY Blacks are more likely than whites to experience the deaths of multiple family members and experience them at earlier ages. Between 1970-2004, an estimated 2.7 million excess black deaths occurred because of blacks’ elevated mortality rates. Further, the estimated 600,000 COVID-19 de…
DEV PRIYA ARYA · NUBAD, LLC · 2024 · $999,707 — PROJECT SUMMARY Aminoglycosides are one of the cheapest and well-known antibiotics in clinical use for over 70 years, but one of the major limitations in their use is their ototoxicity. We are developing fast and low-cost methods to develop aminoglycosides with anti-ribosomal activities and reduced…
Neha Neelam Goel · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $187,879 — PROJECT SUMMARY The goal of Dr. Neha Goel’s K23 project is to enable her to become an independent physician-investigator who conducts research on the implementation of evidence-based care for patients with acute respiratory failure. Building upon her strengths as a pulmonary-critical care physician…
Federico Costa · YALE UNIVERSITY · 2024 · $741,011 — PROJECT SUMMARY Although new variants may contribute to surges, we expect SARS-CoV-2 to transition to a new phase where the virus continues to circulate but at lower levels. Sequential immunizing exposures, whether due to infection or vaccination, have transformed the immune status of populations by…