Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Matthew C. Altman · BENAROYA RESEARCH INST AT VIRGINIA MASON · 2024 · $2,283,860 — SUMMARY/ABSTRACT – OVERALL Acute respiratory viral infections (ARVI) are the most frequently occurring global illness producing significant morbidity and mortality, particularly in vulnerable populations. Children suffer higher frequencies of ARVI and often experience re-infections. Common chronic d…
Efren Flores · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $280,777 — PROJECT SUMMARY Candidate: This resubmission for the NCI K08 Mentored Clinical Scientist Research Career Development Award to Promote Diversity describes Efrén J. Flores, MD as a candidate who is well- positioned to successfully complete the proposed training objectives and research aims. Dr. Flores…
David Changli WEI · UNIVERSITY OF TEXAS MED BR GALVESTON · 2024 · $606,134 — Summary Viral infection is a major contributor to the global burden of infectious diseases. Virus-related glomerular diseases are seen in increasing frequency in clinical practice but are still underrecognized, thus miss opportunities for timely treatment. Viral exposure can alter host immunity in s…
Billy Tsai · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $381,397 — Abstract SARS-CoV-2 exploits the function of the endoplasmic reticulum (ER) to promote its infection life cycle. Despite its strong reliance on the ER, the molecular basis by which SARS-CoV-2 hijacks ER factors to promote defined steps of this life cycle remains unclear. Using infectious SARS-CoV-2,…
Gordon Raphael Bernard · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $10,954,065 — Contact PD/PI: Bernard, Gordon R The Vanderbilt Institute for Clinical and Translational Research (VICTR) is a highly functional and integrated clinical and translational (C&T) research infrastructure that has raised the quality and scientific rigor of the research conducted at Vanderbilt and longst…
Felice Le-Scherban · DREXEL UNIVERSITY · 2024 · $619,860 — PROJECT SUMMARY Nearly 14% of US households with children were food insecure before the start of the COVID-19 crisis, and this number increased dramatically during the pandemic. Food insecurity (FI)— inadequate access to enough food for every person in a household to live an active, healthy life—thr…
Brandon A Knettel · DUKE UNIVERSITY · 2024 · $166,317 — The proposed K08 Career Development Award will provide Dr. Knettel with the training and mentorship to become an independent clinical scientist focused on developing novel, yet scalable mental health interventions in resource-limited settings. The objective of the proposed research is to assess the …
Thomas E Lane · UNIVERSITY OF CALIFORNIA-IRVINE · 2024 · $846,461 — Abstract: An important unmet clinical need for patients with the demyelinating disease multiple sclerosis (MS) is an effective method for promoting remyelination that can ameliorate clinical symptoms associated with demyelination and restore motor function while limiting immune cell infiltration int…
Daniel A Hackman · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $637,055 — Project Summary Neighborhoods are an important ecological context for child and adolescent development and a social determinant of physical health, mental health, and school achievement. Research has begun to elucidate the associations between neighborhood characteristics and brain structure, functi…
Laura Forsberg White · BOSTON UNIVERSITY MEDICAL CAMPUS · 2024 · $412,500 — PROJECT SUMMARY The “Tools for Transmission of Agents and Conditions (TRAC)” program will synergize statistical and mathematical modeling work in three areas of application: 1) Tuberculosis (TB) incidence and transmission; 2) monitoring substance use disorder (SUD) patterns; and 3) SARS CoV-2 transm…
Dawon Baik · UNIVERSITY OF COLORADO DENVER · 2024 · $172,823 — PROJECT SUMMARY/ABSTRACT My career goal is to establish an independent aging research program focused on designing and evaluating high quality, technology-based behavioral health interventions to improve self-management and quality of life (QoL) of community-dwelling older adults, particularly older…
Swathi Kiran · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · 2024 · $38,878 — PROJECT ABSTRACT The annual Academy of Aphasia meeting is the premier conference for researchers in the field of language processing and aphasia. Since the first meeting in 1963, this international meeting has brought together an interdisciplinary group of linguists, psychologists, neurologists, and…
Jianxin You · UNIVERSITY OF PENNSYLVANIA · 2024 · $353,134 — Project Summary Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly aggressive form of skin cancer. Immune suppression is one of the most important risk factors for developing MCPyV-associated MCC. MCPyV has a far greater chance to ind…
Kate Suzanne Carroll · UNIVERSITY OF FLORIDA · 2024 · $1 — PROJECT SUMMARY Antibiotics are central to modern medicine and rising antibiotic resistance is one of the biggest threats to global health. Identifying new and different drug targets for the development of new antibiotics is crucial to overcome resistance. Adjuvant strategies that either enhance the…
ELIZABETH S BURNSIDE · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $8,885,006 — Contact PD/PI: Brasier, Allan OVERALL ABSTRACT. This application is for renewal for the Clinical and Translational Science Award (CTSA) at the University of Wisconsin-Madison (UW) Institute for Clinical and Translational Research (ICTR). Through meaningful collaborations with partnering schools and …
Allison Marie Greaney · YALE UNIVERSITY · 2024 · $76,756 — PROJECT SUMMARY/ABSTRACT Fibrotic lung remodeling is a hallmark of many lung diseases, including severe influenza infection, idiopathic pulmonary fibrosis, and COVID-19. While a basal-like epithelial cell has been identified as a central player to this aberrant repair response, little has been done …
DAVID G DRUBIN · UNIVERSITY OF CALIFORNIA BERKELEY · 2024 · $1,028,708 — PROJECT SUMMARY Proposed are complementary studies on the mechanisms and regulation of clathrin-mediated endocytosis (CME) and actin force generation during CME in budding yeast and human stem cells. CME is responsible for uptake of molecules from a cell's environment through the permeability barrie…
CARLOS G GRIJALVA · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $224,548 — ABSTRACT Children tend to experience more frequent asymptomatic infections and milder illnesses associated with SARS-CoV-2 infections than adults, but the reasons for these age-associated differences are unclear. While typical patterns of respiratory syncytial virus, influenza, and other viruses we…
JOSHUA A BRESLAU · RAND CORPORATION · 2024 · $689,268 — This is a service-user informed mixed-methods study of the implementation and impacts of the Certified Community Behavioral Health Clinic (CCBHC) program in New York State. CCBHCs are comprehensive outpatient behavioral health clinics that were originally authorized by Congress in 2014, through a fe…
Judith Ann Callan · BEHAIVIOR INC. · 2024 · $780,183 — Project Summary/Abstract Opioid addiction affects people of all races, ages, gender identities, education, and income levels across the United States. The epidemic has been intensifying in recent years, with relapse rates reaching close to 91% (Kadam et al., 2017) and provisional data from 2020 indi…