Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Laura Lynn Gonzalez · DYNAMOID, INC. · 2024 · $1,036,415 — Across the country, students are unengaged and unmotivated in science classes, resulting in lowered self-efficacy and decreased interest in further STEM classes or STEM careers. For schools, falling test scores and fewer STEM courses offered affect rankings and the ability to attract students and st…
Deborah J Lenschow · WASHINGTON UNIVERSITY · 2024 · $777,498 — OVERALL ABSTRACT The WU-RDRRC seeks to advance the health of patients with rheumatic diseases by supporting enabling technology and promoting the members’ basic, clinical, and translational research interests that are organized around three major themes: 1) elucidating basic mechanisms of inflammat…
Erez Eitan · NEURODEX INC · 2024 · $942,163 — PROJECT SUMMARY In this Fast Track SBIR application, NeuroDex, Inc. proposes to use its expertise in extracellular vesicle (EV) immunoaffinity isolation to develop a blood test that detects synucleinopathies with high sensitivity, with the long- term goal of helping clinicians identify patients for …
JEFFERY J AULETTA · NATIONAL MARROW DONOR PROGRAM · 2024 · $1,072,951 — Project Summary Severe combined immunodeficiency (SCID) is a group of genetic disorders that abrogate T cell development and function. Allogeneic hematopoietic cell transplantation (HCT) is the standard treatment for the disease and can be performed successfully in SCID patients without the high do…
Julie Anne Boom · BAYLOR COLLEGE OF MEDICINE · 2024 · $1,234,285 — Component A: Project Summary Texas Children’s Hospital (TCH) aims to continue inpatient and emergency department surveillance as part of the larger national New Vaccine Surveillance Network (NVSN) to assess the burden of pediatric respiratory and gastrointestinal illnesses and acute flaccid myelitis…
Daniel R. Kuritzkes · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · 2024 · $301,913 — The Dual bNAb Treatment in Children Study (“Tatelo”) is an ongoing phase I/II, multi-site clinical trial of dual treatment with two broadly neutralizing monoclonal antibodies (bNAbs), VRC01LS and 10-1074, offered to HIV-1 infected virally suppressed children. The study is evaluating the efficacy o…
Adam Lee Bailey · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $243,505 — PROJECT SUMMARY/ABSTRACT As COVID-19 has illustrated, the emergence of novel RNA viruses from wild animals poses a significant threat to human health. In this proposal, we will begin to assess the zoonotic potential of an entire family of viruses: the arteriviruses. The arteriviruses are the only ma…
Darby E. Saxbe · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $353,073 — PROJECT SUMMARY The COVID-19 pandemic has had sweeping effects on pregnant women and their partners. The need to adhere to social distancing guidelines has altered the social connectedness of expectant parents, with effects on stress, loneliness, reduced access to in- person prenatal care, and chil…
Sarah E. Millar · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $731,611 — Project Summary/Abstract Infection of the olfactory epithelium in COVID-19 patients is thought to underlie loss of smell (anosmia), a pathognomonic symptom that can be long-term in some patients, significantly affecting quality of life. The olfactory epithelium is also believed to be a major entry p…
Jiandi Wan · UNIVERSITY OF CALIFORNIA AT DAVIS · 2024 · $224,955 — Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, debilitating disease with inconclusive causes and no laboratory-based diagnostic tests. Oxygen tension (PO2)-regulated red blood cell (RBC) capillary velocity has emerged recently as a new mechanism regulating cerebral capilla…
JENNIFER M LOFTIS · PORTLAND VA MEDICAL CENTER · 2024 — Among the concerns of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the development of neurological manifestations of post-acute sequelae of SARS-CoV-2 infection (PASC) or neuro- PASC. Research shows that neuropsychiatric impairments, including cognitive problems, depr…
Roger Bedimo · VA NORTH TEXAS HEALTH CARE SYSTEM · 2024 — Neurologic symptoms are among the most common post-acute sequelae of COVID-19 (PASC). Recent studies show that there is a very high rate of neurocognitive changes among Veterans surviving acute COVID- 19 infection. The long-term neurocognitive changes of this infection could be even worse and remain…
Anju Paudel · PENNSYLVANIA STATE UNIVERSITY, THE · 2024 · $230,194 — PROJECT SUMMARY About 25% of daily care interactions between staff and residents in long-term care including Assisted Living Facilities (ALFs) comprise of poor care interactions. Individuals with Alzheimer’s disease and related dementias (ADRD) are especially at risk for poor care interactions relat…
Melanie Lynn Kornides · UNIVERSITY OF PENNSYLVANIA · 2024 · $592,790 — Project Summary Background: Misinformation on social media, or the sharing of false or incomplete information without intent to cause harm, is contributing to vaccine hesitancy among parents and impeding uptake of the HPV vaccine among adolescents in the United States. Innovative communication strat…
GILL DIAMOND · TULANE UNIVERSITY OF LOUISIANA · 2024 · $737,561 — Abstract Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a life-threatening illness with multi-system involvement in a subset of infected individuals. Oral and nasopharyngeal (NP) epithelial cells express the SARS-CoV-2 receptor…
Cheryl Hogue · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · 2024 · $655,597 — Project Summary/Abstract. We seek to establish the Undergraduate Research Initiative for Student Enhancement (U-RISE) program at California State University, Northridge (CSUN). We use a growth mindset as a scaffolding for the activities and interventions we propose in this new program. The future of…
Anne Elizabeth Fehrenbacher · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $182,088 — PROJECT SUMMARY/ABSTRACT Anne E. Fehrenbacher, PhD, MPH is a social epidemiologist in the Department of Psychiatry and Biobehavioral Sciences at the University of California, Los Angeles and a Fogary GloCal Fellow at the Public Health Research Institute of India. Dr. Fehrenbacher’s long-term career…
Barun Mathema · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $632,098 — Project Summary Despite renewed public health efforts, including more effective treatment, tuberculosis (TB) incidence has reduced only incrementally, an effect driven by the inability to contain community TB transmission. Early identification and treatment of infectious individuals is central to br…
Deok-Ho Kim · CORNELL UNIVERSITY · 2024 · $237,913 — PROJECT SUMMARY Blood vessels play a central role in maintaining host immunity by transporting immune cells to sites of infection. During the process, blood vessels experience endothelial junction remodeling to control vascular permeability and immune cell extravasation. Under infection, blood vesse…
Michael Tse-Yin Lu · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $1,195,255 — Project Summary/Abstract This proposal will support the Data Coordinating Center (DCC) for the Randomized Trial to Prevent Vascular Events in HIV Trial (REPRIEVE) Extension for up to two additional years, with an additional year for study close-out. This additional time is necessary to collect the m…