Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Linnea Ariel Zimmerman · JOHNS HOPKINS UNIVERSITY · 2024 · $81,875 — Project Summary The goal of this research is to inform the development of adolescent health programs through understanding the development and trajectories of empowerment over the course of adolescence, among girls and boys, and quantifying how this process influences sexual and reproductive health …
Justin D Russell · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $138,735 — 1. PROJECT SUMMARY/ABSTRACT Candidate: I am presently a scientist in the BRAVE Research Center (BRC), within the Department of Psychiatry at the University of Wisconsin (UW). Career Goals: I seek to identify neural mechanisms though which childhood adversity can perturb typical development of biobeh…
Samantha L Martin · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $166,746 — Abstract Children with in-utero exposure to hypertensive disorders of pregnancy (HDP; gestational hypertension, chronic hypertension, preeclampsia, and superimposed preeclampsia) have an increased risk for hypertension and cardiovascular disease (CVD). Our preliminary data indicate that administerin…
Kelly Bakulski · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $638,611 — PROJECT SUMMARY The rising prevalence of Alzheimer's disease and related dementias (ADRD) is a major public health and clinical challenge in the United States. Identification of ADRD causes to inform prevention and policy is the most efficient way to address these challenges. Most research to date h…
KRISTA M PERREIRA · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $615,646 — Project Summary/Abstract Hispanic/Latino sexual and gender minorities (SGM) are the fastest growing ethnic group of SGM in the U.S. Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among Hispanic/Latinos. SGM inequities in cardiovascular disease (CVD) risk have been identif…
MARK MERCOLA · STANFORD UNIVERSITY · 2024 · $569,291 — Ventricular arrhythmia and sudden cardiac death (SCD) is a prevalent complication of hypertrophic cardiomyopathy (HCM) especially in young adults. Pathogenic variants of sarcomeric protein genes cause about half of inherited HCM and about a third of sporadic HCM. Little is known, however, about how …
Paul S Park · CASE WESTERN RESERVE UNIVERSITY · 2024 · $415,554 — Abstract Phototransduction is a fundamental biological process involving a set of biochemical reactions in photoreceptor cells initiating vision. The long-term goal of this research program is to understand the molecular mechanisms underlying the biochemical events in phototransduction under normal…
Randy B. Stockbridge · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $195,000 — PROJECT SUMMARY/ABSTRACT The problem: Dental caries is the leading health condition worldwide, affecting billions of people and causing pain, impaired nutrition and social functioning, reduction in work/school productivity, and significant economic impacts. For the most vulnerable groups, such as ch…
JOHN V. MORAN · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $319,163 — Abstract Long INterspersed Element-1 (LINE-1 or L1) transposable element derived sequences comprise approximately 17% of human genomic DNA. Although the overwhelming majority of LINE-1s have been rendered immobile by mutational processes over evolutionary time, an average human genome contains appr…
Elliott M Weiss · SEATTLE CHILDREN'S HOSPITAL · 2024 · $160,283 — PROJECT SUMMARY/ABSTRACT Neonatal clinical trials have difficulty including diverse populations of infants. Parents of infants who are racial or ethnic minorities, report lower income, or have lower educational attainment are less often approached, more likely to decline enrollment, and more likely …
RADHAKRISHNA RAO · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · 2024 · $495,570 — Alcohol-related diseases and disorders (ADD) account for over 5% of global health problems, and alcohol abuse is a causal factor in more than 200 diseases. Endotoxemia and systemic inflammation are common conditions associated with morbidity and mortality in various ADD. Extensive clinical and exper…
Ruschelle Marie Leone · GEORGIA STATE UNIVERSITY · 2024 · $185,220 — PROJECT ABSTRACT The overarching goal of this Mentored Research Scientist Career Development Award (K01) is to provide Dr. Ruschelle Leone with the training and research activities needed to become an independent investigator. Her program of research will focus on developing and evaluating innovativ…
Woon Ju Park · UNIVERSITY OF WASHINGTON · 2024 · $125,992 — Project Summary/Abstract Early blindness results in dramatic neuroplasticity within the human brain; anatomical and functional organization is altered at almost every level, ranging from neurotransmitter balance to neural function. I plan to combine psychophysics, computational functional magnetic r…
Daniel Lench · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2024 · $127,386 — Project Summary/Abstract Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) is an established therapy for PD patients with motor fluctuations and dyskinesias. While STN DBS is an effective treatment for motor symptoms, it can produce unintended side effects cognition including exec…
Sophia A. Hussen · EMORY UNIVERSITY · 2024 · $683,730 — PROJECT SUMMARY Emerging data demonstrates a rise in methamphetamine (meth) use among Black gay, bisexual and other men who have sex with men (GBMSM). Meth is associated with myriad physical and social harms, and has the potential to exacerbate existing health inequities impacting Black GBMSM. Exist…
Zirui Huang · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $516,464 — SUMMARY The overall goal of this work is to understand the neural basis of human consciousness and its modulation by anesthetic agents. State and contents are two aspects of consciousness that have been mostly studied independently. State refers to an organism's overall conscious condition that has …
Tian Qin · UT SOUTHWESTERN MEDICAL CENTER · 2024 · $324,060 — Project Summary/Abstract Cross-coupling reactions provide the most reliable and modular means to diverse chemical space, enabling the discovery of novel pharmaceuticals and elucidation of critical biological pathways. Seminal efforts spanning the last century have led to the development of a variety…
Takeo Watanabe · BROWN UNIVERSITY · 2024 · $398,750 — Summary This is a resubmission of the competitive renewal of the ongoing R01 grant. Visual perceptual learning (VPL) is an important tool that can be used to better understand visual plasticity. The long-term goal is to comprehensively understand the mechanisms of VPL and their underlying plasticity…
Matthew J. Flick · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $734,117 — SUMMARY/SCOPE OF WORK BACKGROUND AND SIGNIFICANCE: Thrombotic diseases are the leading cause of death and disability worldwide. Genetic, environmental, and pharmacological factors, as well as acute and chronic inflammatory diseases, are linked to exacerbated thrombosis. Despite this heterogeneity of…
Lopa Mishra · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · 2024 · $443,383 — PROJECT SUMMARY Alcohol-related liver disease (ALD) and nonalcoholic steatohepatitis (NASH) are two reasons Americans mostly require a liver transplant. Furthermore, aldehyde dehydrogenase gene 2 (ALDH2) deficiency, which impairs alcohol and lipid metabolism, affects ~560 million people globally. Ou…