Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Sara Elizabeth Hamilton Hart · UNIVERSITY OF MINNESOTA · 2024 · $517,948 — Project Summary/Abstract The Mouse and Infection Models Core (Core B), will be directed by Dr. Hamilton Hart, with Dr. Niedernhofer as Co-I. This is an integral component of the PPG. The Core will be utilized by all three proposed projects and will allow PPG investigators to examine senescence and d…
LAURA Jane NIEDERNHOFER · UNIVERSITY OF MINNESOTA · 2024 · $541,140 — Senescent cells (SnCs) increase in tissues with age and are established to play a causal role in aging and age- related conditions/syndromes. SnCs confer their adverse effects, at least in part, through their senescence- associated secretory phenotype (SASP), which is pro-inflammatory. A particularl…
Janice M. Mehnert · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $391,425 — PROJECT SUMMARY/ABSTRACT The Perlmutter Cancer Center (PCC) Clinical Protocol and Data Management Core (CPDM) standardizes, manages, and reports on all cancer-related human subjects research across the NYU Langone Health (NYULH) network. CPDM also delivers education and training services for researc…
Reuben Shaw · SALK INSTITUTE FOR BIOLOGICAL STUDIES · 2024 · $354,588 — PROJECT SUMMARY – ADMINISTRATION The Salk Cancer Center (SCC) has a longstanding tradition of exceptional basic and translational science research. SCC Administration (ADMIN) provides critical infrastructure and carries out a diverse set of functions to ensure that all SCC activities run smoothly an…
Dana Dolinoy · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $543,307 — SUMMARY/ABSTRACT (Administrative Core) The Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) mission has two overarching goals: to accelerate research that defines and explains impacts of environmental exposures during vulnerable stages of life, and to promote translation of…
Mark Morris Davis · STANFORD UNIVERSITY · 2024 · $132,036 — PROJECT SUMMARY The administrative core of the Stanford CCHI has been highly successful in the past almost twenty years in its leadership and coordination of center activities, management of finances and resources, and facilitation of intra-center collaboration and scientific support. The continu…
KENNETH D STUART · SEATTLE CHILDREN'S HOSPITAL · 2024 · $349,031 — Scientific Project 1: Immune Responses to Pre-erythrocytic Malaria Vaccination or Infection Abstract This project will identify and characterize key characteristics of human immune responses to the pre-erythrocytic (PE) falciparum malaria infection and vaccination that targets this stage with a focu…
Ramnik J Xavier · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $250,499 — Project Summary/Abstract (Collaborative Project) In this project a set of recently developed experimental and computational tools for antigen discovery will be utilized to identify antigens of microbial and self origin in IgG4-related disease and in systemic sclerosis. The focus will be to identify …
Karen E Kim · UNIVERSITY OF CHICAGO · 2024 · $398,169 — PROJECT SUMMARY/ABSTRACT - COMMUNITY OUTREACH AND ENGAGEMENT COMPONENT (COE) The mission of University of Chicago Medicine Comprehensive Cancer Center (UCCCC) Community Outreach and Engagement Component (COE) is to promote equitable cancer care and inform, facilitate, and disseminate relevant resear…
Kathryn M. Anastos · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2024 · $680,084 — PROJECT SUMMARY ERC-CFAR: CLINICAL AND TRANSLATIONAL SCIENCE CORE (CTSC) To help meet the vision of Ending the HIV Epidemic (EHE), the Einstein-Rockefeller-CUNY Center for AIDS Research (ERC-CFAR) has formed strong collaborations both within and beyond our partner institutions, including the New Yor…
Priya B. Shete · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $175,652 — PROJECT SUMMARY – Clinical Science Core Progress towards meeting global public health tuberculosis (TB) targets for reductions in incidence, mortality and catastrophic costs have been slow, and appear to have stagnated due the recent COVID-19 pandemic. Without reinvigorating TB clinical research wit…
Wade Williams · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2024 · $155,680 — ADMINISTRATIVE CORE: ABSTRACT The Administrative (Admin) Core at the Stephenson Cancer Center (SCC) provides administrative support for all SCC research components and activities – including programs, members, shared resources, and other infrastructure – with the goal of operationalizing research in…
Xiu-Min Li · GENERAL NUTRACEUTICAL TECHNOLOGY, LLC · 2024 · $894,193 — ABSTRACT Food allergy (FA) has rapidly increased over 2 decades affecting 32 million Americans, with annual costs of $25 billion. FA anaphylaxis, a potentially life-threatening condition, increased 200-400% in children from toddlers to teens.10 Peanut/ tree nut and sesame allergy often co-exist, la…
Yale E Cohen · UNIVERSITY OF PENNSYLVANIA · 2024 · $326,946 — Although there is a rich history relating single-neuron spiking activity to brain function, our understanding of the neural bases of perception and behavior depends on identifying information processing within neuronal circuits that operate over different spatial scales. Despite their importance as …
Yi Yin · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $390,000 — PROJECT SUMMARY/ABSTRACT Homologous recombination (HR) is important for repairing DNA double strand breaks (DSB), and thus is an essential process in embryonic development, meiosis and suppressing tumorigenesis. HR can also be a double- edged sword: unrepaired breaks lead to cell death; errors by H…
Zhenghui Gordon Jiang · BETH ISRAEL DEACONESS MEDICAL CENTER · 2024 · $686,264 — SUMMARY Alcohol-associated hepatitis (AH) is a form of subacute liver failure with high mortality, limited treatment options, and elusive pathogenesis. Emerging evidence suggests that AH is associated with a profound impairment in hepatocellular cholesterol homeostasis. Hepatocytes are the central …
Eva Billerbeck · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2024 · $420,000 — Inflammatory liver diseases such as chronic hepatitis C virus (HCV) infection can progress to liver fibrosis and hepatocellular carcinoma (HCC). Hepatic T cell immunity is closely linked to liver diseases since T cells are not only essential for the clearance of hepatotropic viruses like HCV but may…
Xuan Anna Li · UNIV OF MARYLAND, COLLEGE PARK · 2024 · $185,452 — Project summary/abstract Reducing rates of relapse after abstinence is a key challenge for curbing the ongoing opioid epidemic. One of the common factors for triggering relapse is re-exposure to drug-associated cues. In rats, cue-induced oxycodone seeking progressively intensifies (incubates) over …
Andreana Natalie Holowatyj · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $568,895 — SUMMARY Despite the number of adults within their child-bearing years diagnosed with, treated for, and surviving colorectal cancer (CRC), reproductive health concerns stand as an unmet care need among adults ages 18 to 49 years with CRC (early-onset CRC) and their families. This is because there is …
Jennifer Below · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $679,562 — SUMMARY Dilated cardiomyopathy (DCM) affects up to 1:250 individuals and is responsible for ~40% of cardiac transplants. Guidelines recommend genetic testing in DCM probands to help establish diagnosis, guide medical care, inform risk stratification, and identify at-risk relatives. However, causal v…