Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Sally Lynn Hodder · WEST VIRGINIA UNIVERSITY · 2022 · $768,858 — West Virginia (WV), the only state located entirely in Appalachia, has the lowest life expectancy in the nation and ranks at or near the bottom in many chronic disease categories. The WV Clinical and Translational Science Institute (WVCTSI) was created in 2012 through the initial Institutional Devel…
ELLEN L BURNHAM · UNIVERSITY OF COLORADO DENVER · 2022 · $96,728 — Project Summary The proposed supplement will augment an established R24 Alcohol Research Resource, known as CoPARC (Colorado Pulmonary-Alcohol Research Collaborative), that has served as a human participant and patient biorepository supporting translational investigations at the intersection of alco…
Cynthia Y Tang · UNIVERSITY OF MISSOURI-COLUMBIA · 2022 · $39,032 — Project Summary The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has resulted in over 5 million deaths worldwide. As the burdens of the pandemic in the United States (US) shift from urban to rural communities, preliminary …
Jason W. Botten · CELDARA MEDICAL, LLC · 2022 · $290,738 — Summary Accelerating emergence and re-emergence of a wide array of viral epidemics has been a deadly feature of the 21st century. Potent or even effective therapies are rarely available to combat these diseases, and in general, the world remains unprepared to manage future outbreaks. The most recent…
Christoph Juchem · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2022 · $1,094,475 — While 1 in 5 children are at risk for psychiatric disorders, only 1 in 20 young children receive mental health care. There remains a gap in knowledge of early causes and precursor symptoms of psychiatric disorders; therefore, many children are not identified as at risk until school age, when a diagn…
Ivona Vasile Pandrea · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2022 · $396,980 — Abstract With more than 60 million SARS-CoV-2 -infected patients worldwide and nearly 1.5 million COVID-19-related deaths recoreded thus far (November 25), the COVID pandemic is one of the most critical global health problem ever known to humankind, and a major emergency in the US. COVID-19 disprop…
STEVEN A BENNER · FOUNDATION FOR APPLIED MOLECULAR EVOLUTN · 2022 · $313,900 — Easily Used Kits to Evolve Reagents that Covalently Tag and Inactivate Proteins Foundation for Applied Molecular Evolution Steven Benner ABSTRACT Under PAR-19-253, the NIGMS seeks new technologies that create a positive feedback loop that drives science forward by allowing new questions to be ask…
BRUCE E BOWLER · UNIVERSITY OF MONTANA · 2022 · $670,730 — Project Summary Montana is a geographically large and predominantly rural state with 12 Tribal nations. From the beginning of the SARS-CoV-2 pandemic through the spring of 2021, Montana was severely under-represented in national sequencing databases—and specifically in rural areas—limiting the state…
Alessandro Sette · LA JOLLA INSTITUTE FOR IMMUNOLOGY · 2022 · $2,391,540 — Project Summary – Overall The La Jolla HIPC team will focus on pathogens causing infectious diseases of the upper and lower respiratory tract that lead to substantial mortality and morbidity. Our approach is unique and innovative, as it focuses on defining immune signatures (IMS) of antigen-specifi…
Chawangwa Modongo · UNIVERSITY OF CALIFORNIA-IRVINE · 2022 · $596,211 — Project Summary The emergence and spread of SARS-CoV-2 variants of concern is threatening global health and our ability to prevent COVID-19 disease, raising concerns about a potential new wave of the pandemic. HIV may complicate the trajectory of the COVID-19 pandemic and efforts to eradicate the vi…
Leonard A Jason · DE PAUL UNIVERSITY · 2022 · $200,734 — Abstract This proposal would allow us to compare EBV and SARS-CoV-2 immune markers and metabolomics on the samples from our unique data sets. Immune and metabolomic analyses are interesting discovery tools and an important aspect of the integrative approach we will use, with their broad and flexible…
Peter B. Gilbert · FRED HUTCHINSON CANCER CENTER · 2022 · $293,711 — Project Abstract This proposal outlines the scientific agenda for the Leadership and Operations Center of the HIV Vaccine Trials Network (HVTN), the collaboration of physician scientists at 64 clinical trial sites in 15 countries on 4 continents dedicated to developing globally effective vaccines fo…
Scott C Weaver · UNIVERSITY OF TEXAS MED BR GALVESTON · 2022 · $987,497 — ABSTRACT As underscored by pandemic COVID-19, Zika, yellow fever and chikungunya viruses, new and emerging viruses represent increasing threats to human health, yet their mechanisms of emergence remain poorly understood, and effective interventions are not available for most. Research on their patho…
HENRY PAUL PARKMAN · TEMPLE UNIV OF THE COMMONWEALTH · 2022 · $1 — PROJECT SUMMARY Patients with gastroparesis often suffer with chronic symptoms that are not adequately treated due to both a lack of understanding of the underlying pathophysiology of gastroparesis and lack of effective treatments. Participation of Temple University as a clinical center in the NIDDK…
William Messer · OREGON HEALTH & SCIENCE UNIVERSITY · 2022 · $44,999 — A cluster of respiratory illness that emerged in December, 2019 in Wuhan China marked the arrival of novel coronavirus Severe Acute Respiratory Syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19. SARS-CoV-2 infection presents with a spectrum of symptoms, ranging from asymptomatic, …
MEREDITH C. B. ADAMS · UNIVERSITY OF ROCHESTER · 2022 · $756,521 — PROJECT SUMMARY Opioid use disorder (OUD) is a serious national crisis that affects public health and economic welfare, even prior to the COVID-19 pandemic. The COVID-19 pandemic and the mitigation policies to prevent the spread of SARS-CoV-2 upended social networks, healthcare access, led to histor…
Pallavi P Balte · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2022 · $246,750 — Summary/Abstract Tobacco product use has been well established as a major cause of death and disease, yet the public health burden of tobacco in the context of the COVID-19 pandemic – which has already killed more than 700,000 Americans and radically altered behaviors and health in populations acro…
Xueying Yang · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · 2022 · $255,091 — Project Summary/Abstract Effective and durable COVID-19 vaccines hold the potential to dramatically alter the COVID-19 pandemic. Remarkable achievement of COVID-19 vaccine development was observed in large, randomized-controlled trials, where several vaccines were found to be safe and efficacious in…
CRISTINA ELIZABETH DAVIS · UNIVERSITY OF CALIFORNIA AT DAVIS · 2022 · $898,498 — Project Summary/Abstract: This proposal has two major goals: 1) Define signature exhaled breath volatile organic compounds (VOCs) to diagnose SARS-CoV-2 infections, and 2) Develop a portable chemical sensing device that can capture and detect exhaled VOCs and includes machine learning algorithms for…
Hayden C Metsky · BROAD INSTITUTE, INC. · 2022 · $102,577 — Project Summary/Abstract Viral genome sequencing is growing exponentially and cutting-edge molecular technologies, guided by genomic data, show great promise in detecting and responding to viruses. Yet we lack a computational framework that efficiently leverages viral data to design the nucleic or a…