Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
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DEBORAH PHIPPARD · PRECISION BIOSERVICES, INC. · 2020 · $117,253 — This contract provides critically needed comprehensive services related to operation of the NIAID Specimen Repository (NSR), and it will continue to help (1) secure, receive, catalog, process, aliquot, store, and disburse human biological specimens from subjects participating in NIAID-sponsored coho…
Nitin S Baliga · INSTITUTE FOR SYSTEMS BIOLOGY · 2020 · $441,482 — Project Summary The NIAID national protocol intends to enroll at least 1000 COVID19 patients in a study designed to track infected patients through tracking, over time, their immune responses, viral load, and a variety of multi-omic analytes that can provide deep insights into how infection by SARS-…
Julie May Croff · OSU CENTER FOR HEALTH SCIENCES · 2020 · $145,460 — Abstract The pandemic resulting from the emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prompted governmental orders across the U.S. to restrict social interaction to reduce the spread of the virus. Reduced social contact may have adverse effects on individuals in re…
Jonathan D Posner · UNIVERSITY OF WASHINGTON · 2020 · $413,677 — ABSTRACT COVID-19 is a severe respiratory tract infection caused by the newly discovered, and highly contagious, SARS- CoV-2 virus that emerged in late 2019 in Wuhan, China and has infected over 3 million people globally (> 1M US) and has caused over 215,000 deaths (58,000 US). SARS-CoV-2 RNA is the…
Austin Crumpton · CHARLES RIVER ANALYTICS, INC. · 2020 · $99,892 — Project Summary/Abstract The novel coronavirus (SARS-CoV-2) highlights urgent training needs for the emergency first responder community. In response to the ongoing COVID-19 pandemic, the Boston Fire Department (BFD) has reported an increased frequency of firehouse cleaning and decontamination acti…
Becky Lynn Genberg · JOHNS HOPKINS UNIVERSITY · 2020 · $665,811 — Project Summary/Abstract Despite the more than decades long downward trend in HIV incidence among people who inject drugs (PWID), there is cause for alarm due to the COVID-19 pandemic and the instability the response will likely cause, particularly among vulnerable populations. COVID-19 will disrupt…
Joseph F. Peterson · VANDERBILT UNIVERSITY MEDICAL CENTER · 2020 · $900,400 — As the COVID-19 pandemic emerged in early 2020 and rapidly spread across the US, an urgent need developed to improve our current understanding of what factors increase infection risk, likelihood of severe illness, or poor outcomes. Early reports suggest genetics, personal health history, socioeconom…
JERRY H GURWITZ · UNIV OF MASSACHUSETTS MED SCH WORCESTER · 2020 · $717,173 — PROJECT SUMMARY/ABSTRACT: The HCSRN-OAICs AGING Initiative seeks an administrative supplement (PA-18-591/NOT-AG-20-022) to R33AG057806 to address pressing research questions related to prevention, control, management, and treatment of COVID-19 in nursing homes, such as: What are the characteristics …
David W Seal · UNIVERSITY OF WISCONSIN-MADISON · 2020 · $127,201 — PROJECT SUMMARY In response to NOT-DA-20-047, Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements and Urgent Competitive Revisions for Research on the 2019 Novel Coronavirus, our research team proposes increase our understanding of drug use and syringe sharing …
E Wesley ELY · VANDERBILT UNIVERSITY MEDICAL CENTER · 2020 · $868,245 — The NIA-funded BRAIN-ICU-2 Study [Bringing to light the Risk factors And Incidence of Neuropsychological dysfunction (dementia) in ICU Survivors, 2nd Study] will define the relationship between ICU delirium and dementia. The proposed administrative supplement to BRAIN-ICU-2 Study (R01 AG58639) is in…
Roger Detels · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2020 · $110,256 — ABSTRACT COVID-19 cases continue to rise, with over 3,000,000 cases and 130,000 deaths in the US and almost 12 million cases worldwide to date. Manifestations of SARS CoV-2 infection range from asymptomatic to mild, moderate, or severe disease, and primarily affects the lung, but increasing data sug…
KATHLEEN T. BRADY · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2020 · $100,000 — PROJECT SUMMARY – SCTR INSTITUTE Parent Award UL1-TR001450 Since 2009, the South Carolina Clinical and Translational Research Institute (SCTR) has transformed the research environment across South Carolina (SC) by creating a Learning Health System that supports high- quality clinical and translation…
Robert H Tukey · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2020 · $3,759,967 — ABSTRACT San Ysidro sits on the US-Mexico border and has a linguistically and ethnically diverse (91% Latinx) population, which is impacted by significant economic and health disparities. 33% of household incomes are less than $29K/yr, and there is a high rate of the comorbidities linked to poor COV…
D. GEOFFREY VINCE · CLEVELAND CLINIC LERNER COM-CWRU · 2020 · $406,488 — Cleveland Clinic (CC) and its partners Case Western Reserve University, Cincinnati Children's Hospital Medical Center, The Ohio State University and University of Cincinnati have a longstanding commitment and documented success in transitioning laboratory and clinical innovations into dramatic impro…
CARL A LATKIN · JOHNS HOPKINS UNIVERSITY · 2020 · $163,364 — Project Summary The SARS-CoV-2 (COVID-19) epidemic has been rapidly changing. Vulnerable populations, such as people who use drugs (PWUD), are particularly susceptible both to severe COVID-19 illness as well as health and well-being consequences associated with the secondary impacts of the COVID-19 …
Matthew C. Altman · BENAROYA RESEARCH INST AT VIRGINIA MASON · 2020 · $543,574 — Project Summary/Abstract This application is being submitted to PA-20-135 in accordance with NOT-AI-20-034. We are requesting an emergency supplement to R01AI32774 “Mechanisms of IL-6 mediated T cell pathogenesis in autoimmunity” (PI: Jane H. Buckner). This supplement will directly address the NOT-A…
Conall Michael O'Cleirigh · MASSACHUSETTS GENERAL HOSPITAL · 2020 · $166,958 — Early data indicate that smoking increases the severity of coronavirus disease (COVID-19) symptoms. Individuals living with HIV are more likely to smoke and less likely to quit than those in the general population, placing them at high risk for poor COVID-19 outcomes. Comorbidities associated with H…
DANIEL K. BENJAMIN · DUKE UNIVERSITY · 2020 · $869,057 — PROJECT SUMMARY/ABSTRACT The impact of the current COVID-19 global pandemic is likely underestimated. The specific impact on pregnant women, their infants and children is even less well characterized. We will use the infrastructure of the Duke / Vanderbilt Trial Innovation Center to address these kn…
Joseph A. Sparano · MONTEFIORE MEDICAL CENTER (BRONX, NY) · 2020 · $149,833 — The parent grant of this supplement is the ANal Cancer/HSIL Outcomes Research (ANCHOR) Study, a large multi-site randomized clinical trial and protocol of the AIDS Malignancy Consortium (AMC), UM1CA121947. It is designed to determine if identification and treatment of anal high-grade squamous intrae…
PEI TANG · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2020 · $156,491 — The alpha7 nicotinic acetylcholine receptor (α7nAChR) has emerged as a unique player in the infection and progression of COVID-19, which has caused more than 325,000 deaths. α7nAChR links tobacco smoking to major clinical manifestations in COVID-19, including respiratory infection, anosmia, systemic…