Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Shyamasundaran Kottilil · UNIVERSITY OF MARYLAND BALTIMORE · 2020 · $154,500 — Risk factors for developing severe illness/acute respiratory distress syndrome from coronavirus disease 2019 (COVID-19) include older age, male gender, and underlying conditions, currently identified as smoking, chronic lung disease or moderate to severe asthma, heart disease with complications, sev…
Angela Robertson Bazzi · BOSTON UNIVERSITY MEDICAL CAMPUS · 2020 · $107,979 — PROJECT SUMMARY/ABSTRACT This application is being submitted in response to NOT-DA-20-047. Injection drug use has contributed to new HIV outbreaks in many regions of the United States. The parent K01 award seeks to improve the delivery of antiretroviral pre-exposure prophylaxis (PrEP) to people who …
J DOUGLAS COATSWORTH · UNIVERSITY OF TENNESSEE KNOXVILLE · 2020 · $125,036 — The novel coronavirus disease (COVID-19) pandemic of 2020 has disrupted normal daily functioning for people across the globe as governments have sought to limit community spread of the disease. Because the virus affects the respiratory tract, individuals with compromised lung function, such as those…
Michael S Glickman · WEILL MEDICAL COLL OF CORNELL UNIV · 2020 · $353,106 — The COVID-19 pandemic has now spread from high- and middle-income countries to low-income countries, including Haiti and Tanzania. The natural history of COVID-19 is unknown in low-income countries. We propose to study a combined cohort of 3,054 adults in Haiti and Tanzania to determine the attack r…
Linda B. Cottler · UNIVERSITY OF FLORIDA · 2020 · $130,357 — SUMMARY OF PARENT GRANT AND PROPOSED SUPPLEMENT Parent Study: Through our parent U01, our National Drug Early Warning System (NDEWS) Coordinating Center aims to provide NIDA and the field with the most timely, salient, and valuable information on emerging substance use trends. By expanding data coll…
Joshua Glenn Petrie · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2020 · $42,992 — PROJECT SUMMARY / ABSTRACT The COVID-19 pandemic has strained hospital capacity and led to shortages in personal protective equipment and testing supplies. This is particularly concerning because the SARS-CoV-2 virus that causes COVID-19 has resulted in notable healthcare associated outbreaks, as ha…
Christopher G Kevil · LOUISIANA STATE UNIV HSC SHREVEPORT · 2020 · $191,038 — PROJECT SUMMARY/ABSTRACT The present project is part of the Centers of Biomedical Research Excellence (COBRE) grant focused on research on redox biology mechanisms of cardiovascular disease. The objective of the COBRE Center for Redox Biology and Cardiovascular Disease is to establish a nationally r…
Jean-Laurent Casanova · ROCKEFELLER UNIVERSITY · 2020 · $371,507 — Project Summary In December 2019, a novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, China, and quickly spread worldwide, with an increasing number of cases and deaths. In populations naive to this new pathogen, there has been immense inter-individual clinical variability among infected …
Christina Ruth Studts · UNIVERSITY OF COLORADO DENVER · 2020 · $189,453 — PROJECT SUMMARY/ABSTRACT COVID-19 has unleashed a sudden and sustained disruption to usual healthcare and social milieu in the United States, and of particular concern are deaf/hard of hearing (DHH) children who rely on hearing healthcare and ancillary services for access to auditory language and ot…
Jessica A Hamerman · BENAROYA RESEARCH INST AT VIRGINIA MASON · 2020 · $253,182 — PROJECT SUMMARY Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the presence of circulating autoantibodies to nucleic acids and to proteins with which they associate. Signaling through the nucleic acid sensing TLRs, TLR7 and TLR9, is critical in SLE pathogenesis,…
STEVEN M KOGAN · UNIVERSITY OF GEORGIA · 2020 · $148,354 — Project Summary/Abstract The young Black men who are the focus of the proposed Urgent Competitive Revision to R01AA026623 are from small towns and rural communities in Georgia, an area of persistent poverty for Black residents that coincides with the nation’s worst educational, economic, and health …
Feifan Yu · ALPHATHERA, INC. · 2020 · $547,186 — The speed and extent of COVID-19 pandemic, caused by the SARS-CoV2 virus, have created unprecedented devastations and challenges. It is now well-established that timely and accurate diagnosis is essential to taming this pandemic. Unlike PCR based tests, which can only diagnose active infections, ser…
Andrew Slator Paterson · LUMINOSTICS, INC. · 2020 · $718,866 — Abstract In this Emergency Supplemental project, Luminostics will leverage our de-risked and scale-ready CLIP platform to develop a rapid smartphone-based point-of-care (POC) diagnostic for the detection of SARS-CoV-2 antigens from respiratory specimens. Luminostics' CLIP technology enables high-sen…
Hak Soo Choi · MASSACHUSETTS GENERAL HOSPITAL · 2020 · $651,080 — Project Summary/Abstract (limit within 30 lines) The COVID-19 emerged in December 2019 and then spread rapidly over 214 countries. As of May 15, 2020, a total of more than 4.5M confirmed cases and over 300,000 deaths have been reported worldwide, posing significant health and economic threats to ou…
Dermot Patrick McGovern · CEDARS-SINAI MEDICAL CENTER · 2020 · $346,893 — The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), are significant causes of morbidity with recent estimates suggesting there are more than 3 million Americans with IBD with very significant financial burden to the US economy. The world is currently in the middl…
CRAIG B THOMPSON · SLOAN-KETTERING INST CAN RESEARCH · 2020 · $177,000 — Novel Coronavirus 2019 SARS-CoV-2 (COVID-19) infection is a global pandemic disease that has severely affected the United States. Emerging data suggests that racial and ethnic minority groups are disproportionately affected by COVID-19 and African Americans (AA) are overrepresented among hospitalize…
Bruce Y Lee · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · 2020 · $322,626 — PROJECT SUMMARY ABSTRACT With the ongoing COVID-19 coronavirus pandemic, the potential environmental transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of significant concern, especially in hospitals. Choosing and coordinating the right approaches (e.g., environmental cl…
Eliver Ghosn · EMORY UNIVERSITY · 2020 · $359,677 — SUMMARY COVID-19 disease is an ongoing global pandemic caused by a new beta-coronavirus SARS-CoV- 2. A major obstacle to battling SARS-CoV-2 is a better understanding of the human innate immune responses that can lead to an uncontrolled hyper-inflammation in the lung and, ultimately, to an acute res…
VASILIS VASILIOU · YALE UNIVERSITY · 2020 · $150,625 — Abstract The induces flu-like treatment health, 1,919,430 societal people COVID-19. disease means infected extremely ventilators, SARS-CoV-2 . We propose to identify alterations in the plasma metabolome of patients experiencing different levels of severity of COVID-19. Such changes should be pivotal…
Nicholas J. Mantis · WADSWORTH CENTER · 2020 · $1,153,230 — Project Summary As the COVID-19 pandemic continues to spread across the United States it is imperative that we implement technologies to screen large swaths of the population for the presence of antibodies to SARS-CoV-2. Serological surveillance not only affords a measure of virus exposure within a …