Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Ferenc Livak · DIVISION OF BASIC SCIENCES - NCI · 2022 · $1,677,497 — The mission of the CCR LGI Flow Cytometry Core in Building 37 (FC37) is to offer up-to-date instrumentation and technical expertise to CCR investigators to assist cancer research. The core provides full-scale, state-of-the-art flow cytometry services including analytical sample acquis…
Daniel S Chertow · CLINICAL CENTER · 2022 — Project 1: We previously developed a NHP ICU model in healthy (uninfected) NHPs. We have extended this model to included supportive care of animals infected with E.coli or K. pneumoniae. Among K. pneumoniae infected animals, we have completed initial bacterial dose-response studies and are now proc…
Parizad Torabi-Parizi · CLINICAL CENTER · 2022 — Coronavirus disease 19 (COVID-19) is a rapidly growing health threat in the United States with a fatality rate ten times greater than with seasonal influenza. The virus is highly transmissible and has rapidly infected large numbers of people in China, in several European countries, and now in the US…
Alexander Bukreyev · UNIVERSITY OF TEXAS MED BR GALVESTON · 2022 · $361,188 — ADMINISTRATIVE CORE (Core A): PROJECT SUMMARY/ABSTRACT The Administrative Core is responsible for the strategic planning, overall management, and coordination of the Program Project (P01) “Molecular Mechanisms of the Dysregulated Immune Response to Ebola Virus”. It provides governance, financial ove…
Kevin Michael Tuohey · BOSTON UNIVERSITY MEDICAL CAMPUS · 2022 · $1,900,368 — Core 3: Environmental Health and Biosafety Regulations and Requirements Abstract The Environmental Health and Biosafety Regulations and Requirements (EHBRR) Core includes three components: Environmental Health and Safety, Emergency Management, and Occupational Medicine. The Core is integrated with c…
ANKITA GARG · UNIVERSITY OF GEORGIA · 2021 · $547,000 — PROJECT SUMMARY/ABSTRACT Investigators at UGA have established national and international recognition for their research on high- containment pathogens of global importance. UGA investigators are working towards understanding pathogenesis and developing newer vaccines, therapeutics and diagnostics t…
KENNETH M KAUFMAN · CINCINNATI VA MEDICAL CENTER RESEARCH · 2021 — The new Covid-19 virus is deadly for 0.2% to 4% of people infected, with older men the most severely afflicted with this scourge, being mortal to ~15% of those infected over 80 years, making the US Veteran population especially vulnerable. It is critically important to understand the mechanisms of t…
Junki Maruyama · UNIVERSITY OF TEXAS MED BR GALVESTON · 2021 · $113,977 — PROJECT SUMMARY/ABSTRACT This career development award will help fill in the knowledge and skills in basic virological research of Risk Group 4 agents, which need to be handled in the highest containment laboratory (BSL-4). This is essential for the goal to become an independent researcher as an exp…
David Alland · RBHS-NEW JERSEY MEDICAL SCHOOL · 2021 · $3,328,439 — PROTECT ABSTRACT The Rutgers University Regional Biocontainment Laboratory (RBL) serves as a central facility to perform biosafety level three (BSL3) research for academic and commercial entities within Rutgers University, the Northeast United States, and beyond. Heavily used for high-threat pathoge…
Jakob Trimpert · KANSAS STATE UNIVERSITY · 2021 · $3,430,993 — SUMMARY: Kansas State University (KSU) is well-positioned to become the preeminent institution to advance the discovery and development of biosecurity strategies for emerging and zoonotic infectious diseases. With KSU’s Biosecurity Research Institute (BSL-3), USDA’s Arthropod-Borne Animal Disease Re…
Christopher F Basler · GEORGIA STATE UNIVERSITY · 2021 · $180,913 — Project Summary Filoviruses, which include the ebolaviruses and marburgviruses, are non-segmented, negative-sense RNA viruses (NNSVs) that cause severe human disease. These viruses are of concern as emerging pathogens and as potential bioterrorism threats. Their importance and public health impact a…
Parizad Torabi-Parizi · CLINICAL CENTER · 2021 — Coronavirus disease 19 (COVID-19) is a rapidly growing health threat in the United States with a fatality rate ten times greater than with seasonal influenza. The virus is highly transmissible and has rapidly infected large numbers of people in China, in several European countries, and now in the US…
JILL E HUTCHCROFT · PURDUE UNIVERSITY · 2021 · $82,914 — Flow Cytometry Shared Resource (FC-SR) Project Summary The Purdue Flow Cytometry Shared Resource (FC-SR) provides advanced cell and particle analysis, cell sorting and single cell genomic capabilities to members of the Purdue University Center for Cancer Research (PCCR). The FC-SR has made major i…
Alexander Bukreyev · UNIVERSITY OF TEXAS MED BR GALVESTON · 2021 · $80,593 — ADMINISTRATIVE CORE (Core A): PROJECT SUMMARY/ABSTRACT The Administrative Core is responsible for the strategic planning, overall management, and coordination of the Program Project (P01) “Molecular Mechanisms of the Dysregulated Immune Response to Ebola Virus”. It provides governance, financial ove…
Ricardo Rajsbaum · UNIVERSITY OF TEXAS MED BR GALVESTON · 2021 · $395,000 — The most recent outbreak of Ebola virus (EBOV) in West Africa reached alarming numbers of infections and deaths, prompting extensive efforts to develop antiviral strategies; however, none have thus far been approved for use in humans. The development of antiviral drugs is mostly based on designing c…
Lijun Rong · CHICAGO BIOSOLUTIONS, INC. · 2021 · $982,388 — Ebola (EBOV) and Marburg (MARV) viruses belong to the Filoviridae family and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction after an incubation period of 4-14 days. Due to safety concerns, these viruses are designated as biosafety level 4 agents. Currently, there i…
DAVID Branch MOODY · BRIGHAM AND WOMEN'S HOSPITAL · 2021 · $223,260 — The Metabolomics Core (B) is comprised of a Biosafety Level 3 suite for handling infectious samples, massively parallel detection of mycobacterial metabolites using Time of Flight mass spectrometry (Agilent Accurate Mass ToF 6230), specialized resources for identifying known mycobacterial compound…
Alexander Bukreyev · UNIVERSITY OF TEXAS MED BR GALVESTON · 2021 · $215,591 — BSL-4 CORE (Core B): PROJECT SUMMARY/ABSTRACT The pathogenesis of Ebola virus (EBOV) disease is characterized by a dysregulated immune response that includes the suppression of the innate immune system leading to “immune paralysis” and paradoxically activation of inflammatory pathways characteristic…
Juergen A Richt · KANSAS STATE UNIVERSITY · 2021 · $2,266,526 — Overall Project Summary: This COBRE application will form a unique research center on Emerging and Zoonotic Infectious Diseases (EZID). Four primary research projects bridge areas of excellence in the Infectious Diseases programs at Kansas State University (KSU) within the Colleges of Arts and Scien…
Thomas William Geisbert · UNIVERSITY OF TEXAS MED BR GALVESTON · 2021 · $1,415,990 — PROJECT SUMMARY/ABSTRACT Nipah virus (NiV) causes febrile encephalitis and severe respiratory disease in humans with fatality rates as high as 100% in some outbreaks (average ~ 75% for outbreaks over the last decade). There are currently no licensed vaccines or therapies for combating NiV disease. N…