Document text
Principal Investigator: David Alland
Organization: RBHS-NEW JERSEY MEDICAL SCHOOL
Fiscal Year: 2021
Award: $3,328,439
Funding agency: National Institute of Allergy and Infectious Diseases
PROTECT ABSTRACT
The Rutgers University Regional Biocontainment Laboratory (RBL) serves as a central facility to perform
biosafety level three (BSL3) research for academic and commercial entities within Rutgers University, the
Northeast United States, and beyond. Heavily used for high-threat pathogen research, this facility is now
confronted with aging systems including those involved in electrical, flooring, ventilation, security and equipment.
These deficiencies place the facility at risk for prolonged shutdowns when repairs or upgrades are needed and
threaten our ability to attract and retain first class scientists. This proposal seeks to rectify these deficiencies,
returning the Rutgers RBL to a state-of-the-art facility and a critical regional resource. This will be performed in
the following aims: 1. Install a second electric feeder cable into the existing double-ended switchgear. 2. Install
new high performance epoxy floor system on new substrate. 3. Upgrade the Johnson Controls Building
Management System (BMS) serving the RBL HVAC equipment. 4. Replace the existing belt-driven high plume
exhaust fans. 5. Replace existing air handling unit (AHU-1,2 & 3) supply fans with fan wall arrays. 6. Install new
keypads at all entry points. 7. Upgrade the video surveillance system. 8. Purchase a portable vaporized hydrogen
peroxide (VH2O2) system to enable selective room and equipment decontamination. 9. Purchase and install a
new state of the art multicolor cell sorter. 10. Purchase a QIAcube instrument to replace manual RNA/DNA
extractions. Together, these upgrades and new purchases will ensure that the Rutgers RBL is able to continue
its mission to support high-threat pathogen research for the current decade and beyond.
Terms: <2019 novel corona virus><2019 novel coronavirus><2019-nCoV><Affect><Aging><Air><Animals><B anthracis><B. anthracis><Bacillus anthracis><Biologic Products><Biological Agent><Biological Products><Books><CHIKV><COVID-19><COVID-19 virus><COVID19><COVID19 virus><CV-19><CV19><Cell Body><Cells><Chikungunya virus><CoV-2><CoV2><Consumption><Contracting Opportunities><Contracts><DNA><Decontamination><Deoxyribonucleic Acid><Diagnostic><Emergencies><Emergency Situation><Ensure><Equipment><F tularensis><F. tularensis><Failure><Floor><Foundations><Francisella tularensis><Frequencies><Future><Grant><H2O2><Hydrogen Peroxide><Hydroperoxide><Immunochemical Immunologic><Immunologic><Immunological><Immunologically><Immunologics><Investigators><Laboratories><Laboratory Research><Length of Life><Life><Longevity><M tb><M tuberculosis><M. tb><M. tuberculosis><Maintenance><Manuals><Mission><Mycobacterium tuberculosis><NIH><National Institutes of Health><Non-Polyadenylated RNA><Pasteurella tularensis><Pathogenesis><Performance><RNA><RNA Gene Products><Research><Research Activity><Research Personnel><Research Resources><Researchers><Resources><Ribonucleic Acid><Risk><SARS corona virus 2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Safety><Scientist><Security><Services><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Stress><System><Therapeutic><Time><Training><United States><United States National Institutes of Health><Universities><Vendor><Work><Wuhan coronavirus><Yellow fever virus><anthracis><biopharmaceutical><biotherapeutic agent><corona virus disease 2019><coronavirus disease 2019><coronavirus disease 2019 virus><equipment acquirement><equipment acquisition><equipment investment><equipment procurement><equipment purchase><equipment purchasing><exhaust><foot><hCoV19><improved><instrument><instrument acquisition><instrument investment><instrument procurement><instrument purchase><laboratory facility><life span><lifespan><mtb><nCoV2><pathogen><portability><repair><repaired><research facility><vapor><ventilation>