Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Jonathan Andrew Kropski · FEDERATION OF AMER SOC FOR EXPER BIOLOGY · 2022 · $40,000 — Project Summary The 2022 FASEB Summer Research Conference, "The Lung Epithelium in Health and Disease", is the 11th biannual conference in this area, bringing together developmental, cell and molecular biologists, geneticists, physiologists, clinicians and translational researchers with a primary in…
LISA A JACKSON · KAISER FOUNDATION RESEARCH INSTITUTE · 2022 · $2,114,527 — The 21-0004 protocol will evaluate the safety and immunogenicity of SARS-CoV-2 administered during pregnancy or postpartum. The Seattle Children’s Research Institute, a subcontractor to the Kaiser Washington VTEU, has been selected to perform SARS-CoV-2 pseudovirus neutralization assays for the 21-0…
Deborah J Donnell · FRED HUTCHINSON CANCER CENTER · 2022 · $389,142 — Abstract The proposed research, CoVPN 5002, will directly contribute to preparedness for SARS-CoV-2 vaccine and other COVID-19 prevention and treatment studies by determining the prevalence of SARS-CoV-2 infection and seroprevalence among samples of individuals at elevated risk as well as the genera…
Larry S. Schlesinger · TEXAS BIOMEDICAL RESEARCH INSTITUTE · 2022 · $7,483,557 — OVERALL ABSTRACT The Mission of the Southwest National Primate Research Center (SNPRC) is to improve the health of our global community through innovative biomedical research with nonhuman primates (NHPs). One way that it achieves this goal is by serving as a global resource to scientists that ca…
PAUL A WADE · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · 2022 · $3,185,628 — The Epigenomics and DNA Sequencing Core Lab provides a variety of services to the NIEHS scientific community. For next-generation sequencing, the core produces hundreds of millions of short sequence reads of individual DNA molecules using the Illumina NovaSeq 6000, NextSeq 500 or Illumina's MiSeq pl…
Steven Holland · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $2,596,620 — The major activities of this research project in the past have centered around using our optimized methods and procedures for imaging rhesus macaques, NZW rabbits, and common marmosets on PET/CT scanners while conducting a variety of chemotherapy and basic immunology experiments in Mtb models. We ha…
Daniel Levy · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · 2022 · $2,703,246 — As part of the Population Sciences Branch (PSB), the Levy Lab conducts genetic and multidimensional omics research focused on cardiovascular disease (CVD) and its risk factors. Two important areas of the Levy Lab's intramural research are: 1) blood pressure (BP) genetics 2) multidimensional omics o…
Joseph Frank · CLINICAL CENTER · 2022 — A CNN architecture was used to create a deep learning-based segmentation model of the liver seen on CT scans of a nonhuman primate (NHP). The CNN architecture was optimized by implementing a feature pyramid network (FPN). This FPN model was then utilized to generalize liver segmentation to other org…
THOMAS E DEVER · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · 2022 · $2,032,638 — We study the mechanism and regulation of protein synthesis in eukaryotic cells. Of special interest are the regulation of protein synthesis by GTP-binding (G) proteins and protein phosphorylation. In addition, we are studying unusual post-translational modifications of the factors that assist the ri…
Jessica Manning · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $38,687 — DESCRIPTIVE EPIDEMIOLOGY TO INFORM THE CAMBODIAN PUBLIC HEALTH RESPONSE TO COVID19 PANDEMIC. NIAID Cambodia ICER quickly repurposed an existing metagenomics pipeline, originally set up for vector-borne diseases, to genetically characterize index cases of COVID-19 in January 2020. At this early pre…
Michael Grigg · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $179,976 — Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the etiologic agent of COVID-19, emerged in 2019 as a public health emergency and global pandemic. SARS-CoV-2 is a linear, non-segmented, capped, polyadenylated positive-sense, single stranded RNA virus related to SARS-CoV and MERS-CoV, t…
Jason Gall · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $4,391,926 — Coronavirus vaccines and protein reagents will be developed at the VPP. The vaccines may be manufactured through the VCMP for human clinical trials in compliance with current Good Manufacturing Practices (cGMP) and released for use in human clinical trials in healthy human volunteers. These vaccines…
Manas Ray · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · 2022 · $1,517,648 — The NIEHS knock out mouse core (KOMC) is a service orientated facility, which aims at helping investigators at the NIEHS to develop animal models to further their research and fulfilling the mission statement of NIEHS. The KOMC aids investigators in generating transgenic mouse models specific for th…
Adrian McDermott · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $2,457,478 — In March 2020 the VIP began working in collaboration with VRC laboratories on the trial readouts for the Phase 1 DMID 20-0003 trial. Later that year the VIP was working within the Operation Warp Speed (OWS) (now called Countermeasures Accelerations Group) testing USG identified CoVID-19 vaccines. T…
Xin Wei Wang · DIVISION OF BASIC SCIENCES - NCI · 2022 · $254,693 — In collaboration with Luigi Notarangelo, MD, Irini Sereti, MD and Andrea Lisco, MD, PhD of NIAID, we are working to determine the landscape of viral exposure signature as the humoral immunological responses to the history of viral infection in COVID-19-positive patients using the VirS…
Kaitlyn Sadtler · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · 2022 · $641,377 — Analysis of SARS-CoV-2 Seroprevalence in the US Population and Rare Disease Patients Previously we established a range of antibody tests to evaluate SARS-CoV-2 seroprevalence (JoCI, 2021, Nat Comms 2021, JID 2021) in the US population (STM 2021, medRxiv) and abroad including Africa and Southeast As…
Wah Chiu · STANFORD UNIVERSITY · 2022 · $3,880,029 — ABSTRACT An integrated Structural Biology Core will be established to enable the Research Projects’ scientists employing state-of-the-art tools for structural determinations from RNA, protein to virus and virus infected cells. This Core is made up of three Subcores including protein production, x-ra…
Matthew Memoli · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $548,539 — Mosquito-borne diseases continue to cause significant morbidity and mortality worldwide despite on-going control efforts. In 2015, there were >200 million cases of malaria worldwide, causing nearly half a million deaths, with most of the deaths occurring among children under the age of 5 years. Mo…
Helen Chun-Hui Su · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $470,537 — These studies have been organized as part of a broader effort among multiple principal investigators in the Intramural Research Programs of NIAID, NIDCR, NCI, and NIAMS, as well as a research collaborative agreement with investigators at the American Genome Center/Uniformed Services University of th…
Stephen Leppla · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2022 · $51,366 — The monoclonal S9.6 antibody has the unique property of recognizing DNA/RNA hybrids in a sequence-independent manner. Previously, we popularized this antibody and made it available to hundreds of researchers. We worked with NIH tech transfer staff to license this antibody to several leading reagent …