Whitesides Group - Publications Page I of 7

Whitesides Group - Publications Page I of 7 The Whitesides Research Group Publications Publications 1962-1969 30. "The reaction of Copper(I) Hydride with Organocopper(I) Compounds", Whitesides, G. M., San Filippo, 3., Jr. , Stedronsky, E. R. and Casey, C. P., J. Am. Chem. Soc., 1969, 91, 6542.6544. 29. "Pseudorotation in (CH3)2NPF4", Whitesides, G. M. and Mitchell, H. L., J. Am. Chem. Soc., 1969, 91, 5384-5386. 28. "1H-13C Spin-Spin Coupling in Transition Metal Hydride Complexes', Whitesides, G. M. and Maglio, G., J. Am. Chem. Soc., 1969, 91, 4980.4986. 27. "Reaction of Lithium Dialkyl- and Diarylcuprates with Organic Halides", Whitesides, G. M., Fischer, W. P., Jr., San Filippo, J., Jr., Bashe, R. W. and House, H. O., J. Am. Chem. Soc., 1969, 91, 4871- 4882. 26. 'The Reaction of threo(CH3)3CCHDCHDFe(CO)2-p-05H5 with Triphenylphosphine", Whitesides, G. M. and Boschetto, D. J., J. Am. Chem. Soc., 1969, 91, 4313-4314. 25. "The Cydotrimerization of 2-Butyne-1,1,1-d3 by Transition Metal Catalysts", Whitesides, G. M. and Ehmann, W. J., J. Am. Chem. Soc., 1969, 91, 3800-3807. 24. "Irradiation of cis,cis-1,5-Cyclooctadiene in the Presence of Copper(I) Chloride", Whitesides, G. M., Goe, G. L. and Cope, A. C., J. Am. Chem. Soc., 1969, 91, 2608.2616. 23. 'Vanadium Nuclear Spin-Lattice Relaxation in p-Tropyliumvanadium(-I)-Tricarbonyl", Whitesides, G. M. and Mitchell, H. L., J. Am. Chem. Soc., 1969, 91, 2245-2250. 22. "Hindered Rotation in Substituted Paracyclophanes", Whitesides, G. M., Pawson, B. A. and Cope, A. C., J. Am. Chem. Soc., 1968, 90, 639.644. 21. "The Cyclotrimerization of 2-Butyne-1,1,1-d3 by Triphenyltris(tetra-hydrofuran)chromium(III)", Whitesides, G. M. and Ehmann, W. J., J. Am. Chem. Soc., 1967, .A9, 804-805. 20. "trans, trans-1,5-Cyclooctadiene", Whitesides, G. M., Goe, G. L. and Cope, A. C., J. Am. Chem. Soc., 1967, 89, 7136.7137. 19. "Pseudorotation in o-Isopropylphenylbis(p,p'-bitolyl)phosphorane", Whitesides, G. M. and Bunting, W. M., J. Am. Chem. Soc., 1967, 89, 6801-6802. 18. "Oxidative Coupling using Copper(I) Ate Complexes", Whitesides, G. M., San Filippo, 3., Jr., Casey, C. P. and Panek, E. 3., J. Am. Chem. Soc., 1967, 89, 5302-5303. 17. "Cydic Polyolefins. XLV. cis,trans-1,5-Cyclooctadiene", Cope, A. C., Howell, C. F., Bowers, 3., Lord, R. C. and Whitesides, G. M., J. Am. Chem. Soc., 1967, 89, 4024-4027. 16. "A Nuclear Magnetic Resonance Study of s-Cyclopentadienyl(triethylphosphine)copper(I)", Whitesides, G. M. and Fleming, J. S., J. Am. Chem. Soc., 1967, 89, 2855-2859. 15. "The Chemistry of Carbanions. XIII. The NMR Spectra of Various Methyl-magnesium Derivatives: Related Substances", House, H. O., Latham, R. A. and Whitesides, G. M., 2 Org. Chem., 1967, 32, 2481-2496. hup://ginwgroup.harvard.cdu/publications 1960s.html 11/6/2008 EFTA_R1_01521507 EFTA02444592 Whitesides Group - Publications Page 2 of 7 14. "Conformational Isomerism in 1-Substituted Derivatives of 3,3-Dimethylbutane", Whitesides, G. M., Sevenair, 3. P. and Goetz, R. W., J. Am. Chem. Soc., 1967, 85; 1135-1144. 13. 'The Stereochemistry of the Thermal Decomposition of Vinylic Copper(I) and Silver(I) Organometallic Compounds", Whitesides, G. M. and Casey, C. P., J. Am. Chem. Sec, 1966, 88, 4541-4543. 12. 'The Chemistry of Carbanions. XII. The Role of Copper in the Conjugate Addition of Organometallic Reagents", House, H. 0., Respess, W. L. and Whitesides, G. M., J. Org. Chem., 1966, 31, 3128.3144. 11. "Nuclear Magnetic Resonance Spectroscopy: The Configurational Stability of Primary Grignard Reagents. Structure and Medium Effects", Whitesides, G. M. and Roberts, J. D., J. Am. Chem. Sac., 1965, 87, 4878-4888. 10. "Nuclear Magnetic Resonance Spectroscopy: Temperature Dependence of the Spectrum of Fluorocyclooctatetraene", Gwynn, D. E., Whitesides, G. M. and Roberts, 3. D., J. Am. Chem. Soc., 1965, 87, 2862-2864. 9. "Magnetic Resonance Spectroscopy: The Configurational Stability of Primary Grignard Reagents. 3,3-Dimethylbutylmagnesium Chloride", Whitesides, G. M., Witanowski, M. and Roberts, J. D., J. Am. Chem. Soc, 1965, 87, 2854.2862. 8. "Nuclear Magnetic Resonance Spectroscopy: The Effect of Solvent on Magnetic Nonequivalence Arising from Molecular Asymmetry", Whitesides, G. M., Grocki, J. J., Holtz, D., Steinberg, H. and Roberts, 3. D., 1 Am. Chem. Soc, 1965, 87, 1058-1064. 7. "Nuclear Magnetic Resonance Spectroscopy: The Effect of Structure on Magnetic Nonequivalence Due to Molecular Asymmetry", Whitesides, G. M., Holtz, D. and Roberts, J. D., J. Am. Chem. Sac, 1964, 86, 2628-2634. 6. "Long-Range Proton Spin-Spin Coupling in Dimethyl Sulfone", Whitesides, G. M. and Roberts, J. D., J. Phys. Chem., 1964, 68, 1583.1584. 5. "Relative Signs of the 31P-1H and 31P-C-1H Nuclear Magnetic Resonance Coupling Constants", Whitesides, G. M., Beauchamp, J. C. and Roberts, J. D., J. Am. Chem. Soc., 1963, 85, 2665-2666. 4. 'The Configurational Stability of Primary Grignard Reagents", Whitesides, G. M., Kaplan, F. and Roberts, J. D., 1 Am. Chem. Soc., 1963, 85, 2167-2168. 3. "Nuclear Magnetic Resonance Spectroscopy. Structure and Dynamic Character of Allylic Grignard Reagents", Whitesides, G. M., Nordlander, J. E. and Roberts, J. D., Disc. Farad. Soc., 1962, 34, 185-190. 2. "Nuclear Magnetic Resonance Spectroscopy: g,g-Dimethylallylmagnesium Bromide", Whitesides, G. M., Nordlander, J. E. and Roberts, J. D., J. Am. Chem. Soc., 1962, 84, 2010-2011. 1. "Nuclear Magnetic Resonance Spectroscopy: Abnormal Splitting of Ethyl Groups due to Molecular Asymmetry, III", Whitesides, G. M., Kaplan, F., Nagarajan, K. and Roberts, J. D., Proc. Nat. Acad. Sol US4, 1962, 48, 1112-1114. hup://ginwgroup.harvard.cdu/publications 1960s.html 11/6/2008 EFTA_R1_01521508 EFTA02444593 Whitesides Group - Publications Page I of 8 The Whitesides Research Group Publications Publicatbns 1970-1979 108. "Conversion of the Adenosine Moieties of RNA to ATP for Use in Cofactor Recycling", Leuchs, H. )., Lewis, J. M., Rios-Mercadillo, V. M. and Whitesides, G. M., J. Am. Chem. Soc, 1979, 101, 5829-5830. 107. "Large-Scale Enzymatic Synthesis of sn-Glycerol 3-Phosphate", Rios-Mercadillo, V. M. and Whitesides, G. M., J. Am. Chem. Soc., 1979, 101, 5828.5829. 106. "A Basis for Orbital Symmetry Rules", Metieu, H., Ross, J. and Whitesides, G. M., Angew. Chem. hit. Ed. Engl., 1979, .18, 377.392. 105. "Preparation and Magnetic Filtration of Polyacrylamide Gel Beads Containing a Ferrofluid and Covalently Immobilized Proteins", Adalsteinsson, 0., Lamotte, A., Baddour, R. F., Colton, C. K., Pollak, A. and Whitesides, G. M., J. Mot. Cat, 1979, 6, 199.225. 104. "Polyacrylamide Gel Entrapment of Adenylate Kinase", Whitesides, G. M., Lamotte, A. L., Adalsteinsson, 0., Baddour, R. F., Chmurny, A. C. and Colton, C. K., J. Hot Cat, 1979, 6, 177- 198. 103. "Conversion of CH2=CHR to CH2=CR'R by Reaction with Cp2TiCl2/AIR'3", Barber, J. J., Willis, C. and Whitesides, G. M., J. Org. Chem., 1979, 44, 3603-3606. 102. "Water-Soluble Complexes of tert-Phosphines and Rhodium(I) as Homogenous Catalysts", Nuzzo, R. G., Feitler, D. and Whitesides, G. M., J. Am. Chem. Soc., 1979, 101, 3683.3685. 101. "SN2 Displacement and Reductive Coupling of Ketones with Olefins in N,N-Diethylacetamide and N-Ethylpyrrolidone", Sowinski, A. F. and Whitesides, G. M., J. Org. Chem., 1979, 44, 2369-2376. 100. 'Thermal Generation of Bis(triethylphosphine)-3,3-dimethylplatinacyclobutane from Dineopentylbis (triethylphosphine)platinum(II)", Foley, P. and Whitesides, G. M., J. Org. Chem., 1979, 101, 2732- 2733. 99. "An Improved Synthesis of Diammonium Acetyl Phosphate", Lewis, J. M., Haynie, S. L. and Whitesides, G. M., J. Org. Chem., 1979, 44, 864.865. 98. "Hydrogenation of Oriented Monolayers of w-Unsaturated Fatty Adds Supported on Platinum", Richard, M. A., Deutch, J. and Whitesides, G. M., J. Am. Chem. Soc, 1978, 104 6613-6625. 97. "Oxidative Addition and Reductive Elimination Reactions Involving Platinum Metallocycles", Young, G. B. and Whitesides, G. M., J. Am. Chem. Soc, 1978, 100, 5808-5815. 96. "Generalized Affinity Chromatography: Enzyme-Sulfonamide Conjugates Can Be Isolated by Adsorption on Immobilized Carbonic Anhydrase", Horowitz, R. and Whitesides, G. M., J. Am. diem. Soc., 1978, 100, 4632.4633. 95. "Bis(2-diphenylphosphinoethyDamine: A Flexible Synthesis of Functionalized Chelating Diphosphines", Wilson, M. E., Nuzzo, R. G. and Whitesides, G. M., J. Am. Chem. Sac, 1978, 100, 2269.2270. 94. "Conversion of a Protein to a Homogeneous Asymmetric Hydrogenation Catalyst by Site-Specith Modification with a Diphosphinerhodium(I) Moiety", Wilson, M. E. and Whitesides, G. M., J. AM http://grnwgroup.harvard.edu/publications 1970s.html I I /6/2008 EFTA_R1_01521509 EFTA02444594 Whitesides Group - Publications Page 2 of 8 Chem. Soc., 1978, 100, 306-307. 93. "Large-Scale Enzyme-Catalyzed Synthesis of ATP from Adenosine and Acetyl Phosphate: Regeneration of ATP from AMP", Baughn, R. L., Adalsteinsson, 0. and Whitesides, G. M., J. Am. Chem. Soc., 1978, 100, 304-306. 92. "Immobilization of Synthetically Useful Enzymes by Condensation Polymerization", Pollak, A., Baughn, R. L., Adalsteinsson, 0. and Whitesides, G. M., J. Am. Chem. Soc., 1978, 100, 302-304. 91. "Large-Scale ATP-Requiring Enzymatic Phosphorylation of Creatine Can Be Driven by Enzymatic ATP Regeneration", Shih, Y.-S. and Whitesides, G. M., J. Org. Chem., 1977, 42, 4165-4166. 90. 'The Stereochemistry of the Peters Reaction (RSO2HgX6RHgX)", Costa, L. C. and Whitesides, G. M., J. Organometal. Chem., 1977, 139, 151-163. 89. -The Location and Mobility of Functional Groups at the Surface of Oxidized, Low-Density Polyethylene Film", Rasmussen, J. R., Bergbreiter, D. E. and Whitesides, G. M., J. Am. Chem. Soc., 1977, 99, 4746-4756. 88. "Introduction, Modification, and Characterization of Functional Groups on the Surface of Low- Density Polyethylene Film", Rasmussen, J. R., Stedronsky, D. R. and Whitesides, G., M., 1 Am. Chem. Soc., 1977, 99, 4736-4745. 87. "Vinylic Radicals are Intermediates in the Oxidation of Vinylic Lithium Reagents to Lithium Enolates by Dioxygen, but not by Lithium tert-Butyl peroxide", Panek, E. 3., Kaiser, L. R. and Whitesides, G. M., J. Am. Chem. Soc., 1977, 99, 3708-3713. 86. "Propane-1,3-di(magnesium halide)", Costa, L. C. and Whitesides, G. M., .1. Am. Chem. Soc., 1977, 99, 2390.2391. 85. "Large-Scale Enzymatic Synthesis with Cofactor Regeneration: Glucose-6-Phosphate", Pollak, A., Baughn, R. L. and Whitesides, G. M., J. Am. Chem. Soc., 1977, 99, 2366-2367. 84. "Rates of Thiol-Disulfide Interchange Reactions between Mono- and Dithiols and Ellman's Reagent", Whitesides, G. M., Ulbum, J. E. and Szajewski, R. P., J. Org. Chem., 1977, 42, 332-338. 83. "Covalent Immobilization of Adenylate Kinase and Acetate Kinase in Polyacrylamide Gels: Enzymes for ATP Regeneration", Whitesides, G. M., Lamotte, A., Adalsteinsson, 0. and Colton, C. L., in Methods in Enzymology, K. Mosbach, Ed., Academic Press, New York, 1976, 44: 887-897. 82. "Affinity Chromatography", Whitesides, G. M. and Nishikawa, A. H., in Applications of Biochemical Systems in Organic Chemistry, Part 2, J. B. Jones, D. Perlman and C. J. Sih, Eds., John Wiley & Sons, New York, 1976, 929-968. 81. "Large-Scale Organic Synthesis Using Cell-Free Enzymes", Whitesides, G. M., in Applications of Biochemical Systems in Organic Chemistry, Part 2, J. B. Jones, D. Perlman and C. J. Sih, Eds., John Wiley & Sons, New York, 1976, 901-927. 80. "Synthesis and Reactions of Dicyclopentadienyltitanium(N) Metallocycles", McDermott, J. X., Wilson, M. E. and Whitesides, G. M., J. Am. Chem. Soc., 1976, 98, 6529-6536. 79. "Thermal Decomposition of Bis(phosphine)platinum(II) Metallocycles", McDermott, J. X., White, J. F. and Whitesides, G. M., 1. Am. Chem. Soc., 1976, 98, 6521.6528. 78. "High-Gradient Magnetic Filtration of Small Particles of Ferro-, Ferri-, and Paramagnetic Catalysts and Catalyst Supports", Hill, C. L., Lamotte, A., Althoff, W., Brunie, 3. C. and Whitesides, G. M., J. Cat., 1976, 43, 53-60. 77. "Convenient Preparations of a 1,2,3,4,5-Pentamethylcyclopentadiene and 1-Ethyl-2,3,4,5- Tetramethylcydopentadiene", Feitler, D. and Whitesides, G. M., Inorg. Chem., 1976, IS, 446-449. 76. "Organic Synthesis Using Enzymes in Two-Phase Aqueous Polymer Systems", Pollak, A. and hup://ginwgroup.harvard.cdu/publications 1970s.html II /6/2008 EFTA_R1_01521510 EFTA02444595 Whitesides Group - Publications Page 3 of 8 Whitesides, G. M., J. Am. Chem. Soc., 1976, 98, 289-291. 75. "Reaction of a,w-diGrignard Reagents with Silver(I) Salts Forms Carbocyclic Rings", Whitesides, G. M. and Gutowski, F. 0., J. Org. Chem., 1976, 41, 2882-2885. 74. "Magnetic Filtration of Small Heterogenous Catalyst Particles: Preparation of Ferrimagnetic Catalyst Supports", Whitesides, G. M., Hill, C. L and Brunie, 3. C. I. E., Peuoess Res. bevel, 1976, 15, 226.227. 73. "Olefins by Reaction of Lithium Dipropenylcuprates with Alkyl Halides: trans-2-Undecene", Linstrumelle, G., Krieger, J. K. and Whitesides, G. M., Org. Syn., 1976, 55, 103-106. 72. 'The Oxidation of Terminal Olefins to Methyl Ketones by Jones' Reagent is Catalyzed by Mercury (II)", Rogers, H. R., McDermott). X. and Whitesides, G. M., 1 Org. Chem., 1975, 40, 3577-3580. 71. "The Reaction of n-Butyllithium and 2,2,6,6-Tetramethylpiperdine Nitroxyl", Whitesides, G. M. and Newirth, T. L., J. Org. Chem., 1975, 40, 3448-3450. 70. "A Dynamic NMR Study of Fluorine Exchange in Liquid SF4", Klemperer, W. G., Krieger, J. K., McCreary, M. D., Muetterties, E. L., Traficante, D. D. and Whitesides, G. M., J. Am. Chem. Soc., 1975, 97, 7023.7030. 69. "Large-Scale Synthesis of Diammonium Acetyl Phosphate", Whitesides, G. M., Siegel, M. and Garrett, P., .1 Org. Chem., 1975, 40, 2516-2519. 68. "Mechanisms of Thermal Decomposition of Transition Metal Organometallic Compounds", Whitesides, G. M., in Organotransition-Metal Chemistry, Y. Ishii and M. Tsutsui, Eds., Plenum Press, New York, 1975, 223-227. 67. "The Synthesis of Fatty Acids Using Organocopper(I) Ate Complexes Derived from Grignard Reagents", Bergbreiter, D. E. and Whitesides, G. M., J. Org. Chem., 1975, 40, 779-782. 66. "Generation and Utilization of Copper(I) Ate Complexes from Diastereomeric and Enantiomeric Alkylmercury Reagents", Bergbreiter, D. E. and Whitesides, G. M., J. Am. aem. Soc., 1974, 96, 4937-4944. 65. "Pseudorotation in Arylbis(4,4'-dimethyl-2,2'-biphenylylene)phosphoranes", Whitesides, G. M., Eisenhut, M. and Bunting, W. M., 1 Am. Chem. Soc., 1974, 96, 5398-5407. 64. "Pseudorotation in XPF4", Eisenhut, M., Mitchell, H. L., Traficante, D. D., Kaufman, R. J., Deutch, J. M. and Whitesides, G. M., J, Am. Chem. Soc., 1974, 96, 5385.5397. 63. "Copper(I) Alkoxides: Synthesis, Reactions, and Thermal Decomposition", Whitesides, G. M., Sadowski, J. S. and Lilbum, J., J. Am. Chem. Soc., 1974, 96, 2829-2835. 62. "Preparation and Reactions of a Titanium(IV) Metallocycle Formation of Cyclopentanone from Ethylene and Carbon Monoxide", McDermott, J. X. and Whitesides, G. M., J. Am. Chem Soc., 1974, 96, 947-948. 61. "Enzymatic Regeneration of ATP from AMP and ADP. Part II: Enzyme Immobilization and Reactor Development", Whitesides, G. M., Chmurny, A., Garrett, P., Lamotte, A. and Cotton, C. K., in Enzyme Engineering, K. E. Pye and L. B. Wingard, Eds., Plenum Press, New York, 1974, 217-222. 60. "Enzymatic Regeneration of ATP from AMP and ADP. Part I: Thermodynamics, Kinetics, and Process Development", Gardner, C. R., Colton, C. K., Langer, R. S., Hamilton, B. K., Archer, M. C. and Whitesides, G. M., in Enzyme Engineering, K. E. Pye and L. B. Wingard, Eds., Plenum Press, New York, 1974, 209.216. 59. "Kinetics of Formation of Alkyl Grignard Reagents: Evidence for Rate-Determining Electron Transfer", Rogers, R. J., Mitchell, H. L. and Whitesides, G. M., 1 Org. Chem., 1974, 39, 857-858. 58. "The Stereoselective Synthesis of 1-Substituted Organometallic Derivatives of 3,3.Dimethylbutane- http://grnwgroup.harvard.cdu/publications 1970s.html 11/6/2008 EFTA_R1_01521511 EFTA02444596 Whitesides Group - Publications Page 4 of 8 1,2-d2", Bock, P. L. and Whitesides, G. M., J. Am. Chem. Soc., 1974, 96, 2826-2829. 57. "The Stereochemistry of Reactions at Carbon-Transition Metal s-Bonds. (CH3)3CCHDCHDFe(CO) 2C5H5", Bock, P. L., Boschetto, D. J., Rasmussen, J. R., Demers, J. P. and Whitesides, G. M., J. Am. Chem. Soc., 1974, 96, 2814-2825. 56. 'The Preparation and Thermal Decomposition of n-Alkyl(tri-n-butyl-phosphine)silver(1) Reagents", Whitesides, G. M., Bergbreiter, D. and Kendall, P. E., J. Am. Chem. Soc., 1974, 96, 2806-2813. 55. 'The Determination of Enantiomeric Purity Using Chiral Lanthanide Shift Reagents", McCreary, M. D., Lewis, D. W., Wernidc D. L. and Whitesides, G. M., J. Am. Chem. Soc., 1974, 96, 1038-1054. 54. "Reactions of Alkylmercuric Halides with Sodium Borohydride in the Presence of Molecular Oxygen", Hill, C. L. and Whitesides, G. M., J. Am. Chem. Soc., 1974, 96, 870-876. 53. "Selectivity in Organic Group Transfer in Reactions and Mixed Lithium Diorganocuprates", Mandeville, W. H. and Whitesides, G. M., J. Org. Chem., 1974, 39, 4O0-405. 52. "The Mechanism of Reaction of Carbon Monoxide with Phenyllithium", Trzupek, L. S., Newirth, T. L, Kelly, E. G., Sbarbati, N. E. and Whitesides, G. M., J. Am. Chem. Soc., 1973, 95, 8118-8133. 51. "Inversion of Configuration in the Bromination of Vinylic Mercurials", Casey, C. P., Whitesides, G. M. and Kurth, J., 1 Org. Chem., 1973, 38, 3406-3410. 50. "The Preparation and Thermal Decomposition of Platinum(II) Metallocycles", McDermott, 3. X., White, 3. F. and Whitesides, G. M., J. Am. Chem. Soc., 1973, 95, 4451-4452. 49. "Reactions of Transition Metal Peroxides with n-Butyllithium", Regen, S. L. and Whitesides, G. M., J. Organornetal Chem., 1973, 59, 293.297. 48. 'The Mechanism of Interchange of the Syn and Anti protons of Tetra(trihaptoallyl)zirconium(N)", Krieger, 3. K., Deutch, J. M. and Whitesides, G. M., Inorg. Chem., 1973, 12, 1535-1545. 47. "ESR Study of the Radical Ions of 1,2,3,4-Tetramethylnapthalene", Gerson, F., Peake, B. M. and Whitesides, G. M., Org. Mag. Res., 1972, 4, 361-363. 46. "Free Radical Intermediates in the Reaction of Neophyllithium with Oxygen", Panek, E. J. and Whitesides, G. M., J. Am. Chem. Soc., 1972, 94, 8768-8675. 45. 'The Stereochemistry of the Conjugate Addition of Derivatives of endo-2-Norbornylcopper(I) to Mesityl Oxide", Whitesides, G. M. and Kendall, P. E., J. Org. Chem., 1972, 37, 3718-3725. 44. "Preparation of Deuterated Organic Compounds from Activated Organic Halides by Reduction with Zinc", Trzupek, L. S., Stedronsky, E. R. and Whitesides, G. M., J. Org. Chem., 1972, 3Z 3300- 3303. 43. "Nitrogen and Boron Spin-Lattice Relaxation in Borazole", Whitesides, G. M., Regen, S. L., Lisle, J. B. and Mays, R., J. Phys. Chem., 1972, 76, 2871-2877. 42. "Mechanism of Thermal Decomposition of Di-n-butylbis(triphenyl-phosphine)platinum(II)", Whitesides, G. M., Gaasch, 3. F. and Stedronsky, E. R., J. Am. Chem. Soc., 1972, 94, 5258.5270. 41. "The Catalytic Oxidation of Vicinal Diols to a-Diketones", Regen, S. L. and Whitesides, G. M., J. Org. Chem., 1972, 37, 1832-1833. 40. "Radical Intermediates in the Thermal Decomposition of Neophyl(tri-n-butylphosphine)silver(I)", Whitesides, G. M., Panek, E. 3. and Stedronsky, E. R., J. Am. Chem. Soc., 1972, 94, 232.240. 39. 'The Determination of Enantiomeric Purity Using Chiral Lanthanide Shift Reagents", Whitesides, G. M. and Lewis, D. W., J. Am. Chem. Soc., 1971, 93, 5914-5916. 38. "Analysis of the 1H NMR Spectrum of Di-n-butyl-2,2-d2 bis(triphenylphos-phine)platinum(II)", hup://ginwgroup.harvard.cdu/publications 1970s.html 11/6/2008 EFTA_R1_01521512 EFTA02444597 Whitesides Group - Publications Page 5 of 8 Whitesides, G. M. and Gaasch, J. F., J. Organometal.Chem., 1971, 33, 241-246. 37. "The Stereochemistry of Reactions Occurring at Iron-carbon s-Bonds", Whitesides, G. M. and Boschetto, D. 3., J. Am. Chem. Soc., 1971, 93, 1529-1531. 36. 'The Thermal Decomposition of Vinylic Copper(I) and Silver(I) Organometallic Compounds", Whitesides, G. M., Casey, C. P. and Krieger, 3. K., J. Am. Chem. Soc., 1971, 93, 1379-1389. 35. 'Trisp-(t-butylhydroxymethylene)-d-camphoratoleuropium(111): a Reagent for Determining Enantiomeric Purity", Whitesides, G. M. and Lewis, D. W., J. Am. Chem. Sx., 1970, 92, 6979- 6980. 34. "The Mechanism of Reduction of Alkylmercuric Halides by Metal Hydrides", Whitesides, G. M. and San Filippo, J., Jr., J. Am. Chem. Soc., 1970, 92, 6611-6624. 33. 'The Mechanism of Formation of 1,2,3,4-Tetramethylnapthalene from 2-Butyne and Triphenyltris (tetrahydrofuran)chromium(III)", Whitesides, G. M. and Ehmann, W. J., J. Am. Chem. Soc., 1970, 92, 5625-5640. 32. "(pbd)p Bonding in Phenyltrichloro-tin, -germane, and -silane", Whitesides, G. M., Selgestad, J. G., Thomas, S. P., Andrews, D. W., Morrison, B. A., Panek, E. J. and San Filippo, 3., Jr., J. Organometal. Chem., 1970, 22, 365-374. 31. "The Mechanism of Thermal Decomposition of n-Butyl(tri-n-butylphosphine)copper(I)", Whitesides, G. M., Stedronsky, E. R., Casey, C. P. and San Filippo, 3., Jr., J. Am. Chem. Soc., 1970, 91, 1426-1427. hup://ginwgroup.harvard.cdu/publications 1970s.html II /6/2008 EFTA_R1_01521513 EFTA02444598 Whitesides Group - Publications Page I of 14 The Whitesides Research Group Publications Publications 1980-1989 273. "Preparation of Cytidine 5'-Monophospho-N-Acetylneuraminic Acid (CMP-NeuAc) and Uridine 5'- Diphosphoglucuronic Acid (UDP-GlcUA); Syntheses of a-2,6-Sialyllactosamine, a-2,6-Sialyllactose, and Hyaluronic Add", Simon, E. S., Toone, E. J., Ostroff, G., Bednarski, M. D. and Whitesides, G. M., in Methods Enzymol.: Complex Carbohydrates, Part F, V. Ginsburg, Ed., 1989, 179, 275.287. 272. "The Synthesis of Aldose Sugars from Half-protected Dialdehydes Using Rabbit Muscle Aldolase", Borysenko, C. W., Spaltenstein, A., Straub, J. A. and Whitesides, G. M., J. Am. aem. Soc., 1989, III, 9275.9276. 271. "Hemagglutinins from Two Influenza Virus Variants Bind to Sialic Acid Derivatives with Millimolar Dissociation Constants: A 500 MHz Proton Nuclear Magnetic Resonance Study", Sauter, N. K., Bednarski, M. D., Wurzburg, B. A., Hanson, J. E., Whitesides, G. M., Skehel, J. 3. and Wiley, D. C., Biochemistry, 1989, 28, 8388-8396. 270. "Lactate Dehydrogenase-Catalyzed Regeneration of NAD from NADH for Use in Enzyme-Catalyzed Synthesis", Chenault, H. K. and Whitesides, G. M., Elloorg. Chem., 1989, 17, 400-409. 269. "Preparation of Phosphoenolpyruvate from D-(-)-3-Phosphoglyceric Acid for Use in Regeneration of ATP", Simon, E. S., Grabowski, S. and Whitesides, G. M., 1 Am. Chem. Soc., 1989, ill, 8920- 8921. 268. "Enzyme-Catalyzed Synthesis of Carbohydrates", Toone, E. J., Simon, E. S., Bednarski, M. D. and Whitesides, G. M., Tet. Rep., 1989, 45, 5365-5422. 267. "The Physical-Organic Chemistry of Surfaces, and Its Relevance to Molecular Recognition", Whitesides, G. M. and Biebuyck, H., in Molecular Recognition: Chemical and Biochemical Problems, S. M. Roberts, Ed., Royal Society of Chemistry, Cambridge, 1989, 78, 270.285. 266. "A New, General Method for the Determination of Binding Constants: Photoacoustic Titration of Dansylamide with Carbonic Anhydrase", Jain, A., Marzluff, E. M., Jacobsen, 3. R., Whitesides, G. M. and Grabowski, 2 1, J. Chem. Soc. Chem. Comm., 1989, 1557-1559. 265. "Orthogonal Systems for Self-Assembled Monolayers: Alkanethiols on Gold and Alkane Carboxylic Acids on Alumina", Laibinis, P. E., Hickman, 3. 3., Wrighton, M. S. and Whitesides, G. M., Science, 1989, 245, 845-847. 264. "Combining Spontaneous Molecular Assembly with Microfabrication to Pattern Surfaces: Selective Binding of Isonitrile to Platinum Microwires and Characterization by Electrochemistry and Surface Spectroscopy", Hickman, 3. 3., Zou, C., Ofer, D., Harvey, P., Wrighton, M. S., Laibinis, P. E., Bain, C. D. and Whitesides, G. M., J. Am. Chem. Soc., 1989, 111, 7271-7272. 263. "Synthesis without Cells", Simon, E. S., Akiyama, A. and Whitesides, G. M., in A Revolution in Biotechnology, J. L. Marx, Ed., ICSU Press, Cambridge, 1989, 15-27. 262. "Modelling Organic Surfaces with Self-Assembled Monolayers", Bain, C. D. and Whitesides, G. M., Angew. Chem. Int. Ed. Engl., 1989, 28, 506-516. 261. 'The Mechanism of Formation of Grignard Reagents: Trapping of Free Alkyl Radical Intermediates by Reaction with Tetramethylpiperidine-N-oxyl", Root, K. S., Hill, C. L., Lawrence, L. M. and Whitesides, G. M., J. Am. Chem. Soc., 1989, 111, 5405-5412. hitp://ginwgroup.harvard.cdu/publications 1980s.html 11/6/2008 EFTA_R1_01521514 EFTA02444599 Whitesides Group - Publications Page 2 of I4 260. "A Study by Contact Angle of the Acid-Base Behavior of Monolayers Containing w- Mercaptocarboxylic Acids Adsorbed on Gold: An Example of Reactive Spreading", Bain, C. D. and Whitesides, G. M., Langmuir, 1989, 5, 1370-1378. 259. "Formation of Monolayers by the Coadsorption of Thiols on Gold: Variation in the Length of the Alkyl Chain", Bain, C. D. and Whitesides, G. M., J. Am. Chem. Soc., 1989, .111, 7164-7175. 258. "Formation of Monolayers by the Coadsorption of Thiols on Gold: Variation in the Head Group, Tail Group, and Solvent", Bain, C. D., Evall, J. and Whitesides, G. M., J. Am. Chem. Soc., 1989, 111, 7155-7164. 257. "Kinetic Resolution of Unnatural and Rarely Occurring Amino Acids: Enantioselective Hydrolysis of N-Acyl Amino Acids Catalyzed by Acylase N, Chenault, H. K., Dahmer, J. and Whitesides, G. M., J. Am. Chem. Soc., 1989, 111, 6354.6364. 256. "D-Lactate Dehydrogenase: Substrate Specificity and Use as a Catalyst in the Synthesis of Homochiral 2-Hydroxy Acids", Simon, E. S., Plante, R. and Whitesides, G. M., App/. Biochem. Biotech., 1989, 22, 169-179. 255. "Structure and Reactivity of Alkylsiloxane Monolayers Formed by Reaction of Alkyltrichlorosilanes on Silicon Substrates", Wasserman, S. R., Tao, Y.-T. and Whitesides, G. M., Langmuir, 1989, 5, 1074-1087. 254. "Monolayers of 11-Trichlorosilylundecyl Thioacetate: A System that Promotes Adhesion between Silicon Dioxide and Evaporated Gold", Wasserman, S. R., Biebuyck, H. and Whitesides, G. M., 1. Mater. Res, 1989, 4, 886-891. 253. "The Structure of Self-Assembled Monolayers of Alkylsiloxanes on Silicon: A Comparison of Results from Ellipsometry and Low-Angle X-Ray Reflectivity", Wasserman, S. R., Whitesides, G. M., Tidswell, I. M., Ocko, B. M., Pershan, P. S. and Axe, J. 0., J. Am. Chem. Soc., 1989, 111, 5852- 5861. 252. "Comparison of Self-Assembled Monolayers on Gold: Coadsorption of Thiols and Disulfides", Bain, C. D., Biebuyck, H. A. and Whitesides, G. M., Langmuir, 1989, 5, 723-727. 251. "Attenuation Lengths of Photoelectrons in Hydrocarbon Films", Bain, C. D. and Whitesides, G. M., 1 Phys. Chem., 1989, 93, 1670-1673. 250. "Characterization and Stability of Cyclic Disulfides and Cyclic Dimeric Bis(disulfides)", Houk, 3. and Whitesides, G. M., Tetrahedron, 1989, 45, 91-102. 249. "Rabbit Muscle Aldolase (RAMA) as a Catalyst in Organic Synthesis", Bednarski, M. D., Simon, E. S., Bischofberger, N., Fessner, W.-D., Kim, M.-3., Lees, W., Saito, T., Waldmann, H. and Whitesides, G. M., 1 Am. Chem. Soc., 1989, .1.11, 627.635. 248. "Enzymatic Baeyer-Villiger Type Oxidations of Ketones Catalyzed by Cyclohexanone Oxygenase", Abril, 0., Ryerson, C. C., Walsh, C. and Whitesides, G. M., Bioorg. Chem., 1989, /7, 41-52. 247. "Oxidation of 2-Propanol to Acetone by Dioxygen on a Platinized Electrode under Open-Circuit Conditions", DiCosimo, R. and Whitesides, G. M., J. Phys. Chem., 1989, 93, 768-775. 246. "Liquid-Phase Oxidation of 2-Propanol to Acetone by Dioxygen Using Supported Platinum Catalysts", Nicoletti, J. W. and Whitesides, G. M., J. Phys. them., 1989, 93, 759-767. 245. "A Combined Chemical-Enzymatic Synthesis of 3-Deoxy-D-arabino-heptulosonic Acid 7- Phosphate", Turner, N. J. and Whitesides, G. M., J. Am. Chem. Soc., 1989, III, 624.627. 244. "Enzymatic Methods for the Preparation of Acetyl-CoA and Analogs", Billhardt, U.-M., Stein, P. and Whitesides, G. M., Bioorg. Chem., 1989, .17, 1-12. 243. "Formation of Monolayer Films by the Spontaneous Assembly of Organic Thiols from Solution onto hup://ginwgroup.harvard.cdu/publications 1980s.html I 1/6/2008 EFTA_R1_01521515 EFTA02444600 Whitesides Group - Publications Page 3 of 14 Gold", Bain, C. D., Troughton, E. B., Tao, Y.-T., Evall, J., Whitesides, G. M. and Nuzzo, R. G., J. Am. Chem. Soc., 1989, 111, 321.335. 242. "The Anthranilate Amide of 'Polyethylene Carboxylic Acid' Shows an Exceptionally Large Change with pH in Its Wettability by Water", Wilson, M. and Whitesides, G. M., J. Am. Chem. Soc., 1988, 110, 8718.8719. 241. "Poly(3-n-butyl-2,5-diethynylenethiophenylene): A Soluble Polymer Containing Diacetylene Units and Its Conversion to a Highly-Cross-Linked Organic Solid", Callstrom, M. R., Neenan, T. X. and Whitesides, G. M., Macromolecules, 1988, 21, 3528-3530. 240. "Hyper-Goss-Linked Organic Solids: Preparation from Poly(aryldiacetylenes) and Preliminary Measurements of their Young's Modulus, Hardness and Thermal Stability", Neenan, T. X., Callstrom, M. R., Scarmoutzos, L. M., Stewart, K. R. and Whitesides, G. M., Macromolecules, 1988, 21, 3525.3528. 239. "Formation of Two-Component Surfaces by the Spontaneous Assembly of Monolayers on Gold from Solutions Containing Mixtures of Organic Thiols", Bain, C. D. and Whitesides, G. M., J. Am. Chem. Soc., 1988, 110, 6560.6561. 238. "Materials for Advanced Electronic Devices", Whitesides, G. M., in Biotechnology and Materials Science: Chemistry for the Future, M. A. Good, Ed., American Chemical Society, Washington, 1988, 85-99. 237. "Depth Sensitivity of Wetting: Monolayers of w-Mercaptoethers on Gold", Bain, C. D. and Whitesides, G. M., J. Am. Chem. Soc., 1988, 110, 5897-5898. 236. "Organic Chemistry in Two Dimensions: Surface-Functionalized Polymers and Self-Assembled Monolayer Films", Whitesides, G. M. and Ferguson, G. S., Chemtracts, 1988, 1, 171-187. 235. "Cofactor Regeneration for Enzyme-Catalyzed Synthesis", Chenault, H. K., Simon, E. S. and Whitesides, G. M., in Biotechnology & Genetic Engineering Reviews, G. E. Russell, Ed., Intercept, Wimborne, 1988, 6, 221-270. 234. "Correlation between Wettability and Structure in Monolayers in Alkanethiols Adsorbed on Gold", Bain, C. D. and Whitesides, G. M., J. Am. Chem. Soc., 1988, 110, 3665-3666. 233. "Synthesis of CMP-NeuAc from N-Acetylgluoosamine: Generation of aP from CMP using Adenylate Kinase", Simon, E. S., Bednarski, M. D. and Whitesides, G. M., J. Am. Chem. Soc. , 1988, 110, 7159-7163. 232. "Synthesis of Analogs of 1,3-Dihydroxyacetone Phosphate and Glyceraldehyde-3-phosphate for Use in Studies of Fructose-1,6-Diphosphate Aldolase", Bischofberger, N., Waldmann, H., Saito, T., Simon, E. S., Lees, W., Bednarski, M. D. and Whitesides, G. M., Journal of Organic Chemistry, 1988, 53, 3457.3465. 231. "Intermolecular Activation of C-D Bonds in Benzene-d6 by trans-Neopentyl (trifluoromethanesulfonato)bis(trimethylphosphine)platinum(I1)", Brainard, R. L., Nutt, W. R., Lee, T. R. and Whitesides, G. M., Organornetallics, 1988, 7, 2379-2386. 230. "Enzymes as Catalysts in Organic Synthesis", Akiyama, A., Bednarski, M., Kim, M.-J., Simon, E. S., Waldmann, H. and Whitesides, G. M., Chemtedi, 1988, 627-634. 229. "Molecular -Level Control over Surface Order in Self-Assembled Monolayer Films of Thiols on Gold", Bain, C. D. and Whitesides, G. M., Science, 1988, 240, 62-63. 228. "The Synthesis of High Carbon Materials from Acetylenic Precursors. Preparation of Aromatic Monomers Bearing Multiple Ethynyl Groups", Neenan, T. X. and Whitesides, G. M., J. Org. Chem., 1988, 53, 2489-2496. 227. "L-Lactate Dehydrogenase: Substrate Specificity and Use as a Catalyst in the Synthesis of Homochiral 2-Hydroxy Acids", Kim, and Whitesides, G. M., 1 Am. Chem. Soc., 1988, 110, hup://ginwgroup.harvard.cdu/publications 1980s.html 11/6/2008 EFTA_R1_01521516 EFTA02444601 Whitesides Group - Publications Page 4 of I4 2959-2964. 226. Vetting of Functionalized Polyethylene Film Having Ionizable Organic Acids and Bases at the Polymer-Water Interface: Relations between Functional Group Polarity, Extent of Ionization, and Contact Angle with Water", Holmes-Farley, S. R., Bain, C. and Whitesides, G. M., Langmuir, 1988, 4, 921-937. 225. "Isotopic Exchange Reactions Occurring in the Hydrogenation of 1,5- Cyclooctadienedialkylplatinum(II) Complexes over Platinum Black", Miller, T. M. and Whitesides, G. M., J. Am. Chem. Soc., 1988, //0, 3164-3170. 224. "Deuterium Labeling Experiments Relevant to the Mechanism of Platinum-Catalyzed Hydrogenation of Diolefindialkylplatinum(II) Complexes: Evidence for Isotopic Exchange via Platinum Surface Hydrogen; the Stereochemistry of Reduction", Miller, T. M., McCarthy, T. J. and Whitesides, G. M., J. Am. Chem. Soc., 1988, 110, 3156.3163. 223. "Heterogeneous, Platinum-Catalyzed Hydrogenation of Diolefindialkylplatinum(II) Complexes: Kinetics", Miller, T. M., Izumi, A. N., Shih, Y.-S. and Whitesides, G. M., J. Am. Chem. Soc., 1988, 110, 3146.3156. 222. 'The Structures of Self-Assembled Monolayer Alms of Organosulfur Compounds Adsorbed on Gold Single Crystals: Electron Diffraction Studies", Strong, L. and Whitesides, G. M., Langmuir, 1988, 4, 546-558. 221. "Monolayer Films Prepared by the Spontaneous Self-Assembly of Symmetrical and Unsymmetrical Dialkyl Sulfides from Solution onto Gold Substrates: Structure, Properties, and Reactivity of Constituent Functional Groups", Troughton, E. B., Bain, C. D., Whitesides, G. M., Nuzzo, R. G., Allara, D. L. and Porter, M. D., Langmuir, 1988, 4, 365-385. 220. "The Use of Enzymes as Catalysts for Synthesis in Medicinal Chemistry: Chiral Synthons and Carbohydrates", Whitesides, G. M. and Kim, M.-J., in New Methods in Drug Research, Vol. 2, A. Makriyannis, Ed., J.R. Prous, Philadelphia, 1988, 1-15. 219. "[Bis(dicydohexylphosphino)ethane]platinum(0): Reactions with Alkyl, (Trimethylsilyfimethyl, Aryl, Benzyl, and Alkynyl Carbon-Hydrogen Bonds", Hackett, M. and Whitesides, G. M., 1 Am. Chem. Soc., 1988, 110, 1449-1462. 218. "The Activation of the C-H Bonds of Benzene by Reaction with [Bis(dicyclo-hexylphosphino) ethane]platinum(0), Generated by the Thermolysis of cis-[Bis(dicyclohexylphosphino)ethane] (hydride)(neopentyl)platinum(II)", Hackett, M., Ibers, J. A. and Whitesides, G. M., 1 Am. Chem. Soc., 1988, 110, 1436-1448. 217. "Generation of Cytidine 5'-Triphosphate Using Adenylate Kinase", Simon, E. S., Bednarski, M. D. and Whitesides, G. M., Tet Lett., 1988, 29, 1123-1126. 216. "Synthesis of 3-Deoxy-D-manno-2-octulosonate-8-phosphate (KDO-8-P) from D-Arabinose: Generation of D-Arabinose-5-Phosphate Using Hexokinase", Bednarski, M. D., Grans, D. C., DiCosimo, R., Simon, E. S., Stein, P. D. and Whitesides, G. M., Tet. Lett., 1988, 29, 427-430. 215. "Carlons: Organic Polymers from Condensation of Carbon Dinudeophiles with Difunctional Derivatives of Carboxylic Acids", Kool, L. B. and Whitesides, G. M., 1 Am. Chem. Soc., 1988, 110, 306-307. 214. "Enzyme-Catalyzed Synthesis of Nucleoside Triphosphates from Nucleoside Monophosphates: ATP from AMP and Ribavirin 5'-triphosphate from Ribavirin 5'-monophosphate", Kim, M.-3. and Whitesides, G. M., Appi. Biochem. Biotech., 1987, 16, 95-108. 213. "Enzymatic Regeneration of Adenosine 5'-Triphosphate: Acetyl Phosphate, Phosphoenylpyruvate, Methoxycarbonyl Phosphate, Dihydroxyacetone Phosphate, 5-Phospho-a-D-ribosyl Pyrophosphate, Uridine-5'-diphosphoglucose", Cans, D. C., Kazlauskas, Ft J., Hirschbein, B. L., Wong, C.-H., Abril, 0. and Whitesides, G. M., in Methods Enzymol.: Immobilized Enzymes/Cells, Pt. C, K. Mosbach, Ed., 1987, 136, 263-80. hup://ginwgroup.harvard.cdu/publications 1980s.html I1/6/2008 EFTA_R1_01521517 EFTA02444602 Whitesides Group - Publications Page 5 of I4 212. "Protein Synthesis in Cell-Free Reticulocyte Lysates on Multi-Hour Incubation", Findeis, M. A. and Whitesides, G. M., App/. Biochem. Biotech., 1987, 15, 169-189. 211. "Placeholder-No publication with this call number",,, 1987.,, 1987. 210. "The Measurement of Thiel-Disulfide Interchange Reactions and Thiol pKa Values", Houk, 1, Singh, R. and Whitesides, G. M., in Methods in Enzymology: Sulfur and Sulfur Amino Acids, W. B. Jakoby and 0. W. Griffith, Eds., Academic Press, New York, 1987, 129-143. 209. "Structure -Reactivity Relations for Thiol-Disulfide Interchange", Houk, J. and Whitesides, G. M., J. Am. Chem. Soc., 1987, log 6825.6836. 208. "What, If Anything, Can Chemistry Offer to Fracture Mechanics?", G. M. and Neenan, T. X., in Chemistry and Physics of Fracture, NATO ASI Series E: Applied Sciences - No. 130, R. M. Latanision, Ed., Dordrecht, 1987, 12-22. 207. "Enzymes in Organic Synthesis", Waldmann, H. and Whitesides, G. M., in Ullmann's Encyclopedia of Industrial Chemistry, A9: 206. "Limited Nerve Impulse Blockade by 'Leashed' Local Anesthetics", Butterworth, 1. F., Moran, J. R., Whitesides, G. M. and Strichartz, G. R.,1. Med. Chem., 1987, 30, 1295-1302. 205. "A Short Synthesis of Ambroxim from Sclareol", Decorzant, R., Vial, C., NM, F. and Whitesides, G. M., Tetrahedron, 1987, 43, 1871-1879. 204. "Enzymes as Catalysts in Practical Organic Synthesis", Akiyama, A., Bednarski, M., Kim, M.-J. S., E.S., Waldmann, H. and Whitesides, G. M., Chem. Britain, 1987, 23, 645-654. 203. "The Enantiomeric Purity of Polar Substrates Can Be Determined with Chiral Lanthanide NMR Shift Reagents in Polar Solvents", Sweeting, L. M., Crans, D. C. and Whitesides, G. M., J. Org. Chem., 1987, 52, 2273-2276. 202. "Fumarase-Catalyzed Synthesis of L-threo-Chloromalic Acid, and Its Conversion to 2-Deoxy-D- Ribose and D-erythro-Sphingosine", Findeis, M. A. and Whitesides, G. M., J. Org. Chem., 1987, 52, 2838-2848. 201. "Regeneration of Nicotinamide Cofactors for Use in Enzymatic Synthesis", Chenault, K. and Whitesides, G. M., App/. Sachem. Biotech., 1987, 14, 147-197. 200. "Enzymatic Routes to Enantiomerically Enriched 1-Butene Oxide", Chenault, H. K., Kim, M.-J., Akiyama, A., Miyazawa, T., Simon, E. and Whitesides, G. M., J. Org. Chem., 1987, 52, 2608-2611. 199. "Membrane -Enclosed Enzymatic Catalysis (MEEC): A Useful, Practical Method for the Manipulation of Enzymes in Organic Synthesis", Bednarski, M. D., Chenault, H. K., Simon, E. S. and Whitesides, G. M., J. Am. Chem. Soc., 1987, 109, 1283-1285. 198. "Reconstruction of the Interface of Oxidatively Functionalized Polyethylene (PE-CO2H) and Derivatives on Heating", Holmes-Farley, S. R., Reamey, R. H., Nuzzo, R., McCarthy, T. J. and Whitesides, G. M., Langmuir, 1987, 3, 799-815. 197. "The Synthesis and Thermolysis of Dimethylbis(trialkylphosphine)-platinum(II) Complexes in Which the Phosphine Ugands Contain Adamantyl, Adamantylmethyl, and Methyl Groups", Hackett, M. and Whitesides, G. M., aganometallia, 1987, 6, 403-410. 196. "The Enzymatic Utilization of Sucrose in the Synthesis of Amylose and Derivatives of Amylose Using Phosphorylases", Waldmann, H., Gygax, D., Bednarski, M., Shangraw, W. R. and Whitesides, G. M., Carbohyd. Res., 1986, 157, c4-c7. 195. 'The Reactivity of Carboxylic Acid and Ester Groups in the Functionalized Interfacial Region of 'Polyethylene Carboxylic Acid' (PE-CO2H) and Derivatives: Differentiation of the Functional Groups into Shallow and Deep Subsets Based on a Comparison of Contact Angle and ATR-IR http://ginwgroup.harvard.cdu/publications 1980s.html I1/6/2008 EFTA_R1_01521518 EFTA02444603 Whitesides Group - Publications Page 6 of I4 Measurements", Holmes-Farley, S. R. and Whitesides, G. M., Langmuir, 1986, 2, 62-76. 194. "Cis(bis(dicyclohexylphosphino)ethane)platinum(0) Reacts with Unactivated Carbon-Hydrogen Bonds", Hackett, M., Ibers, 3. A., Jemakoff, P. and Whitesides, G. M., J. Am. Chem. Soc., 1986, 108, 8094-8095. 193. "Aldolase-Catalyzed Synthesis of Complex CS and C9 Monosaccharides", Bednarski, M. D., Waldmann, H. J. and Whitesides, G. M., Tet. Lett., 1986, 5807.5810. 192. "Synthesis of a Water-Soluble Derivative of Cydohexathacontane-1,2,13,14,25,26-hexone", Mandeville, W. H. and Whitesides, G. M., J. Org. Chem., 1986, 51, 3257-3261. 191. "Radical Isomerization during Grignard Reagent Formation. A Quantitative Treatment", Garst, J. F., Deutch, J. E. and Whitesides, G. M., J. Am. Chem. Soc., 1986, 108, 2490-2491. 190. "Chemistry and Materials Science: Molecular Design and Engineering", Whitesides, G. M., Wrighton, M. S. and Parshall, G., in Advancing Materials Research, National Academy of Sciences, Washington, D.C., 1986, 203-224. 189. "Improved Adhesion of Thin Conformal Organic Films to Metal Surfaces", Stewart, K. R., Whitesides, G. M., Godfried, H. P. and Silvera, I. F., Rev. Sci. Instrum., 1986, 57, 1381.1383. 188. 'The Mechanisms of Thermal Decomposition of trans-Chloroneopentylbis(tricyclopentylphosphine) platinum(II)", Brainard, R. L., Miller, T. M. and Whitesides, G. M., Organometal/ics, 1986, 5, 1481- 1490. 187. "Fluorescence Properties of Dansyl Groups Covalently Bonded to the Surface of Oxidatively Functionalized Low-Density Polyethylene Film", Holmes-Farley, S. R. and Whitesides, G. M., Langmuir, 1986, 2, 266.282. 186. 'The Mechanism of Thermal Decomposition of Bis(tricyclopentylphosphine)-platinacyclopentane (II): Intramolecular b-Hydride Elimination from the Platinacyclopentane Ring is Slow Relative to an Intermolecular Chain Reaction Involving Hydridoplatinum Intermediates", Miller, T. M. and Whitesides, G. M., Organometalks, 1986, 5, 1473-1480. 185. "Preparation of Optically Active 1,2-Diols and a-Hydroxyketones Using Glycerol Dehydrogenase as Catalyst: Limits to Enzyme-Catalyzed Synthesis Due to Non-competitive and Mixed Inhibition by Product", Lee, L. G. and Whitesides, G. M., J. Org. Chem., 1986, 51, 25-36. 184. "Acid-Based Behavior of Carboxylic Acid Groups Covalently Attached at the Surface of Polyethylene: The Usefulness of Contact Angle in Following the Ionization of Surface Functionality", Holmes-Farley, S. R., Reamey, R. H., McCarthy, T. J., Deutch, J. and Whitesides, G. M., Langmuir, 1985, 1, 725.740. 183. "Glycerol Kinase: Synthesis of Dihydroxyacetone Phosphate, sn-Glycerol-3-Phosphate, and Chiral Analogues", Grans, D. C. and Whitesides, G. M., J. Am. Chem. Soc., 1985, 107, 7019-7027. 182. "Glycerol Kinase: Substrate Specificity", Cans, D. C. and Whitesides, G. M., J. Am. Chem. Soc, 1985, 107, 7008-7018. 181. "Enzymes as Catalysts in Synthetic Organic Chemistry", Whitesides, G. M. and Wong, C-H., Angew. Chem. Int. Ed. Engl., 1985, 24, 617-638. 180. "Enzyme-Catalyzed Organic Synthesis: A Comparison of Strategies for in situ Regeneration of NAD from NADH", Lee, L. G. and Whitesides, G. M., J. Am. Chem. Soc., 1985, 107, 6999-7008. 179. "Suppression of Unwanted Heterogeneous Platinum(0)-Catalyzed Reactions by Poisoning with Mercury(0) in Systems Involving Competing Homogeneous Reactions of Soluble Organoplatinum Compounds: Thermal Decomposition of Bis(triethylphosphine)-3,3,4,4- tetramethylplatinacycbpentane", Whitesides, G. M., Hackett, M., Brainard, R. L., Lavalleye, J.-P. P. M., Sowinski, A. F., Izumi, A. N., Moore, S. S., Brown, D. W. and Staudt, E. M., Organometal/ics, 1985, 4, 1819-1830. hup://ginwgroup.harvard.cdu/publications 1980s.html I 1/6/2008 EFTA_R1_01521519 EFTA02444604 Whitesides Group - Publications Page 7 of 14 178. 'The Mechanism of Thermal Decomposition of trans-Chloroethylbis-(triethylphosphine)platinum (II)", Brainard, R. L. and Whitesides, G. M., Organometallics, 1985, 4, 1550-1557. 177. "Enzymatic Synthesis of DeoxyATP Using DNA as Starting Material", Ladner, W. E. and Whitesides, G. M., J. Org. Chem., 1985, 50, 1076.1079. 176. "Organic Synthesis Using Enzymes", Whitesides, G. M., in Organic Chemical Synthesis Using Enzymes, Ciba Foundation Symposium No. 111, Ciba Foundation, London, 1985, 76-90. 175. "Synthesis of Methoxycarbonyl Phosphate, A New Reagent Having High Phosphoryl Donor Potential for Use in ATP Cofactor Regeneration", Kazlauskas, R. J. and Whitesides, G. M., J. Org. Chem., 1985, 50, 1069-1076. 174. "Organic Chemicals from Marine Sources", Whitesides, G. M. and Elliot, J., in Biotechnology in the Marine Sciences, R. M. Colwell, E. R. Pariser and A. J. Sinskey, Eds., John Wiley, New York, 1984, 135-152. 173. "Lipase-Catalyzed Hydrolysis as a Route to Esters of Chiral Epoxy Alcohols", Ladner, W. E. and Whitesides, G. M., J. Am. Chem. Soc., 1984, 106, 7250-7251. 172. "Enzymatic Methods in Organic Synthesis", Findeis, M. A. and Whitesides, G. M., Ann. Rep. Mad Otem., 1984, 19, 263-272. 171. "Enzymatic Synthesis of Arginine Phosphate with Coupled ATP Cofactor Regeneration", Bolte, J. and Whitesides, G. M., thoorg. Chem., 1984, 12, 170-175. 170. "A Practical Enzymatic Synthesis of (SP)-Adenosine 5'-0-(1-Thiotriphosphate)((SP)-ATP-a-S)", Moran, J. R. and Whitesides, G. M., 1 Org. Chem., 1984, 49, 704.706. 169. "Practical Enzymatic Synthesis of Adenosine-5'-O-(3-Thiophosphate)(ATP-g-S)", Abril, 0., Crans, D. C. and Whitesides, G. M., 1 Org. Chem., 1984, 49, 1360-1364. 168. "An Efficient Chemical and Enzymatic Synthesis of Nicotinamide Adenine Dinudeotide (NAD+)", Walt, D. R., Rios-Mercadillo, V. M., Auge, J. and Whitesides, G. M., 1 Am. Chem. Soc, 1984, 106, 234-239. 167. "The Mechanism of Hydrogenolysis of Dineopentylbis(triethylphosphine)platinum(II)", Reamey, R. H. and Whitesides, G. M., J. Am. Chem. Soc., 1984, 106, 81-85. 166. "Organometallic Reactions of Platinum Involving Metallic Hydrides", Whitesides, G. M., Reamey, R. H., Brainard, R. L., Izumi, A. N. and McCarthy, T. J., Annals New York Acad. Sci, 1983, 415, 56- 66. 165. "Chemical Modification of Acrylamide Gels: Verification of the Role of Ionization in Phase Transitions", Nicoll, D., Young, C., Tanaka, T., Pollak, A. and Whitesides, G. M., Macromolecules, 1983, 16, 887-890. 164. "Magnetic Separations in Biotechnology", Whitesides, G. M., Kazlauskas, R. and Josephson, L., 7787ECH, 1983, 1, 144-148. 163. "Practical Synthesis of 5-Phospho-D-ribosyl-a-1-pyrophosphate (PRPP): Enzymatic Routes from Ribose-5-phosphate or Ribose", Gross, A., Abril, 0., Lewis, J. M., Geresh, S. and Whitesides, G. M., 1 Am. Chem. Soc, 1983, 105, 7428-7434. 162. "Enzymes as Catalysts in Organic Synthesis", Whitesides, G. M. and Wong, C-H., Aldrichimica Acta, 1983, 16, 27-34. 161. "A Convenient Synthesis of Disodium Acetyl Phosphate for Use in situ ATP Cofactor Regeneration", Crans, D. C. and Whitesides, G. M., J. Org. Chem., 1983, 26, 3130-3132. 160. "Enzymatic Synthesis of S-Adenosyl-L-Methionine from L-Methionine and ATP", Gross, A., Geresh, hup://gmwgroup.harvard.cdu/publications 1 980s.html 1 1 /6/2008 EFTA_R1_01521520 EFTA02444605 Whitesides Group - Publications Page 8 of I4 S. and Whitesides, G. M., App/. Biochem. Biotech., 1983, 8, 415-422. 159. "Enzyme-Catalyzed Organic Synthesis: Regeneration of Deuterated Nicotinamide Cofactors for Use in Large-Scale Enzymatic Synthesis of Deuterated Substances", Wong, C.-H. and Whitesides, G. M., J. Am. Chem. Soc, 1983, 105, 5012-5014. 158. "Synthesis of Sugars by Aldolase-Catalyzed Condensation Reactions", Wong, C.-H. and Whitesides, G. M., J. Org. Chem., 1983, 48, 3199-3205. 157. "Chemical and Enzymatic Synthesis of 6-Deoxyhexoses. Conversion to 2,5-Dimethy1-4-Hydroxy- 2,3-Dihydro-furan-3-one (FuraneolO) and Analogues", Wong, C.-H. and Whitesides, G. M., J. Org. Chem., 1983, 48, 3493-3497. 156. 155. 154. "Activation Parameters for Thiolate-Disulfide Interchange", Patterson, M. A. IC, 3. Org. Chem., 1983, 48, 112-115. "Relations between Fracture and Coordination Chemistry", Fracture, R. M. Latanision and J. R. Pickens, Eds., Plenum Whitesides, G. M., Houk, J. and Whitesides, G. M., in Atomistics of Press,New York, 1983, 337-362. "Preparation of a Mixture of Nucleoside Triphosphates from Yeast RNA: Use in Enzymatic Synthesis Requiring Nucleoside Triphosphate Regeneration, and Conversion to Nucleoside Diphosphate Sugars", Wong, C.-H., Haynie, S. L. and Whitesides, G. M., J. Am. Chem. Soc, 1983, 105, 115-117. 153. "Enzyme-Catalyzed Synthesis of N-Acetyllactosamine with in situ Regeneration of Uridine 5'- Diphosphate Glucose and Uridine 5'-Diphosphate Galactose, Wong, C.-H., Haynie, S. L. and Whitesides, G. M., J. Org. Chem., 1982, 47, 5416-5418. 152. "Ribulose-1,5-Biphosphate: Routes from Glucose-6-Phosphate (via 6-Phosphogluconate and Ribulose-5-phosphate) and from Adenosine Monophosphate (via Ribose-5-phosphate and Ribulose-5-phosphate)", Wong, C.-H., Pollak, A., McCurry, S. D., Sue, M. M., Knowles, J. R. and Whitesides, G. M., in Methods in Enzymology, W. A. Wood, Ed., Academic Meas, New York, 1982, 108-121. 151. "Asymmetric Synthesis Using Cofactor-Requiring Enzymes", Whitesides, G. M., Wong, C.-H. and Pollak, A., in Asymmetric Reactions and Processes in Chemistry, E. Eliel and S. Otsuka, Eds., American Chemical Society, Washington, D.C., 1982, 185, 1-205. 150. "Synthesis of Phosphoenolpyruvate and Its Use in ATP Cofactor Regeneration", Hirschbein, B. L., Mazenod, F. P. and Whitesides, G. M., 1 Org. Chem., 1982, 47, 3765-3766. 149. "Enzyme-Catalyzed Transhydrogenation between Nicotinamide Cofactors and Its Application in Organic Synthesis", Wong, C.-H. and Whitesides, G. M., 1 Am. Chem. Soc., 1982, 104, 3542- 3544. 148. "Enzyme-Catalyzed Organic Synthesis: NAD(P)H Cofactor Regeneration Using Ethanol/Alcohol Dehydrogenase/Aldehyde Dehydrogenase and Methanol/Alcohol Dehydrog