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Milli-Q® Direct Water Purification System
Pure & ultrapure water directly from tap water
EMD Millipore is a division of Merck KGaA, Darmstadt, Germany
Pure & ultrapure water from a single water system
Scientists’ needs:
Scientists need a system that can deliver pure and ultrapure
water directly from tap water at the right price:
e meeting increasing quality standards
e providing convenience
è optimizing lab space
e allowing low running costs
Optimum water production
Pure water
Tap water is first purified to pure (Type 3) water by reverse osmosis
(RO) using techniques designed and optimized by EMD Millipore:
e Progard® pretreatment cartridge validated to extend the
lifetime of the RO cartridge.
e Reject recirculation loop that recycles reject water treated by the
Progard® to minimize tap water usage (recovery up to 66 %)* and
extend Progard® lifetime while avoiding fouling or scaling issues
that might shorten the RO cartridge lifetime.
e Unique system adaptation to feed water temperature in order to
avoid flow rate decrease during the wintertime when tap water is
colder.
e Unique safety device ensuring that only low ionic permeate
water will be sent to the tank in order to warrant adequate pure
water quality and to increase the lifetime of the ion-exchange
cartridge used to produce ultrapure water.
e Complete process monitoring system that systematically checks
water temperature, pressure, conductivity and RO rejection using
calibrated meters at different steps.
Ultrapure water
e Water is purified in a first step using unique Jetpore® ion-
exchange resin, synthetic activated carbon and a UV lamp
emitting at 185 and 254 nm to reach a resistivity of 18.2 MQ.cm
at 25° and a TOC value below 5 ppb; both values are monitored by
advanced analytical techniques.
e This water is sent through a small recirculation loop to the
Application Pak, where a final purification step, critical for specific
expriments, removes contaminants just before water leaves the
system.
“depending on feed water quality
The Milli-OQ® Direct answer:
The Milli-OQ® Direct is designed as a single water system which produces
pure and ultrapure water directly from tap water. The system:
e exceeds the requirements of the most demanding norms
e provides manual and volumetric water dispense at low and
high flow rate
e has a low footprint: wall-or bench-integrated installation
e allows optimized global costs
The pure water produced by reverse osmosis is stored in a tank
designed to minimize risks of contamination during water
storage. EMD Millipore's tank level sensor will allow the system
to automatically start or stop producing water when you want
to and will accurately display the tank's water level on the
system's screen. Safety devices prevent overflow or the system
from running dry.
From the reservoir, water can be sourced though a front valve,
sent by a delivery pump to feed instruments such as a glassware
washing machine, or further processed by the Milli-Q® Direct
to produce ultrapure (Type1) water.
Convenience in water delivery:
Easily prepare solutions with the
low flow function to precisely
adjust the meniscus in volumetric
flasks.
The 75 cm long tubing reaches the sink
for easy glassware washing at mid or
w~ high flow (up to 2 | per mn).
Save time with the volumetric
function automatically delivering
the water volume you need, and
the dispensing arm designed to
fit the height and shape of all
laboratory glassware.
Deliver water hands-free using the
footswitch option for more convenience.
Select an Application Pak to get the best adapted media for your research:
BioPak®, VOC-Pak™, EDS-Pak®, LC-Pak™, Millipak® polishers.
BioPak® Polisher
Pyrogen-free and
nuclease-free water
Catalogue N°:
CDUFBIOO1
VOC-Pak™ Polisher
Water for volatile
organic compounds
analysis
Catalogue N°:
VOCPAKOO1
EDS-Pak® Polisher
Water for endocrine
disrupters
experiments
Catalogue N°:
EDSPAKOO1
LC-Pak™ Polisher
Water for ultratrace
organic analysis
Catalogue N°:
LCPAKO001
Millipak® Polisher
Bacteria-free and
particulate-free
water
Catalogue N°:
MPGPO4001
Milli-OQ® Direct System at a glance
Dispenser removable from l l
support E High recovery Reverse Osmosis for
Built-in UV 185 nm lamp for pure water production at low cost
TOC reduction & measure
Application Pak adapted
to specific contaminants
removal Large digital & graphic screen with
detailed procedures for full online
support
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Milli-Q |
Progard® pretreatment cartridge to
increase RO module lifetime - with
RFID tag for safety & traceability
Consistent delivery of Ultrapure quality water
adapted to your needs at low or high flow rate
Q-Pak® polishing cartridge
adapted to general application
- with RFID tag for safety &
traceability
Dispenser on support adapted to glassware e
Quick Reference Guide with all
height and shape for automatic volume delivery ul uide wi
needed information in left door
1. Tap water feed 16. Resistivity & temperature measure for ultrapure
2. Inlet Solenoid Valve 9. Permeate conductivity cell water TOC indicator
3. Progard® pretreatment pack 10. 3-way solenoid valve 17. Q-Pak® polishing cartridge
4. Booster pump 11. UV lamp 254 nm (optional) 18. Ultrapure water resistivity and temperature
5. Measure of feed water conductivity and 12. Tank for Type 3 water storage measure
temperature 13. Recirculation & delivery pump 19. Ultrapure water dispenser
6. Reverse Osmosis cartridge(s) 14. UV lamp 185 nm 20. Application Pak polisher adapted to application
7. RO reject recovery loop 15. 3-way solenoid valve - part of the TOC indicator
Easy access to information
e Simplified and detailed information in
(local language).
e Alerts & alarms (which can be enhanced
by a buzzer) are visible on the system's main
screen, with complete information on actions
required accessible at the touch of a finger.
e Sensors regularly monitor the operation of
the system to ensure it operates within speci-
fications. For instance, if ionic contamination
of feed water exceeds specifications, causing
high conductivity, the built-in Feed Water
Conductivity Meter will trigger an alarm to
alert you.
e Clear graphics help you perform specific
tasks such as maintenance. From the same
screen, you can even print reports on the
system's water quality and history.
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e Critical information such as set points or
units is accessible only to the designated
responsible user and is protected by a login
and a password.
e Automatically stop ultrapure water dispense
after a fixed time period set by the user, in
order to avoid water loss or lab flooding.
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A Quick Reference Guide located in the door
of the Milli-OQ® Direct water system provides
all the information required to understand
the operation and maintenance of the system.
The system comes with a complete and
detailed user manual in 8 languages on CD-
ROM. A printed manual contains essential
information in (local language).
Easy and reduced maintenance
Maintenance frequency is minimal, and the procedures are simplified.
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Progard® Pack
replacement
Mi= | i
replacement
» Millipak® Express
40 replacement
Service
e Progard® pretreatment pack or the Q-Pak® polishing cartridge
replacement takes less than 5 minutes.
0-Pak® e Quick and easy traceability thanks to RFID tag which
polishing automatically registers the catalog and other new consumables in
cartridge the system's memory.
e The system will alert you to replace consumables or schedule
service visits at least 15 days before maintenance is actually
required.
EMD Millipore provides a comprehensive range of service programs performed by certified EMD Millipore field
service Support engineers to thoroughly maintain and qualify your Milli-Q® system for full compliance with
your industry's regulatory standards.
The service program portfolio covers all maintenance requirements such as installation, customized user
training, scientific and technical support, troubleshooting, preventive maintenance visits, and all validation
requirements using ad hoc calibrated equipment, procedures, workbooks and suitability tests within a GXPs
environment.
Safety
The Miulli-O® Direct system is tested by an
independent and accredited company for
compliance with the CE directives related to safety
and electromagnetic compatibility.
A certicate is delivered with the system and
the report can be consulted on request at the
manufacturing site.
The Milli-O® Direct system is built using components
and practices recommended by UL and has been cUL
marked. The registration can be verified on the UL
web site (http://www.ul.com).
Certification
The Milli-OQ® Direct system is delivered with a
Certificate of Conformity ensuring that it has been
built and tested fully assembled following EMD
Millipore Standard Operating Procedures, and a
Certificate of Calibration for the temperature and
resistivity meters built in the system. The Milli-Q®
Direct consumables are automatically delivered
with a Certificate of Quality.
EMD Millipore's manufacturing site is ISO 9001
v.2000 and ISO 140001 certified.
MILLI-Q® DIRECT SPECIFICATIONS
Feed Water Specifications Type 3 Water production and delivery
Parameter Value & Unit Parameter Value & Unit
Feed water quality Potable Tap Water Feed 8 |/hour
Feed Water Conductivity < 2000 uS/cm at 25°C Production Flow Rate ic Direct 8)
Feed Water TOC < 2000 ppb (Milli-O® Direct 16)
Feed Water Pressure 1 - 6 bar From tap:
Feed Water Temperature 5- 35°C up to 2.5 I/min
Feed Water Chlorine < 3 ppm(*) Delivery Flow rate ee
Feed Water Fouling Index < 12 up to 15 l/min at
Feed water pH 4 to 10 pH units 1 bar
Feed Water Connection 1/2 in Gaz M
(*) Feed Water Chlorine < 1ppm with Progard® T3 and < 3ppm with Progard® Milli-Q® Direct System Dimensions
T3 + Prepak 1
Parameter Value & Unit
Type 1 Product Water Quality
System footprint 1606 cm2 (249 in2)
Parameter Value & Unit system height l
Sg e Cabinet (base) 497 mm (19.56 in)
Resistivity 18.2 MQ.cm at 25 °C © Dispenser arm (top) 713 mm (28.07 in)
Toc < 5 ppb (ug/l) System width
Bacteria = < 0.1 cfu/ml e Cabinet (base) 332 mm (13.07 in)
PE e Dispenser arm (top) 413 mm (16.25 in)
(endotoxins) "= iliac i t ba 484 mm (19.05 in)
HHKK ® Caoine ase mm . in
RNases < 0.01 ng/ml (RNase-free) e Dispenser arm (top) 581 mm (22.87 in)
DNases**** < 4 pg/ul (DNase-free) 24/25 k
System weight (packaged) 8/16 9
* Resistivity can be displayed temperature-compensated at 25 °C or non- á 2 i 7 (52.91/55.11 Ib)
temperature-compensated as required by USP Syst one ty) 8/16 20/21 kg
* TOC specs - Test Conditions: Milli-O® Direct System equipped with Progard® T3 ee aL ol (44.09/46.29 Ib)
pretreatment pack and Q-Pak® TEX polishing cartridge and with feed (tap) water 27/28 kg
quality within specifications. Product water quality may vary due to local feed System weight (with water) 8/16
water conditions.
*™* Results with Millipak® express 40 or BioPak® final polisher in place
“* Results with BioPak® final polisher in place
(59.52/61.73 Ib)
Dispenser delivery loop length 750 mm (29.52 in)
Electrical power supply cable
290 cm (114.1 in)
. length
Type 1 Water Delivery
Electrical power supply voltage 100 - 230 V + 10 %
Parameter Value & Unit Electrical power supply frequency 50 - 60 Hz + 10 %
. Adjustable between 50 and Feed water connection 1/2 in. Gaz F
Manual dispense flow rate i
2000 ml/min
Data connection Ethernet (RJ45)
100 ml, then 250 ml to 5 |
by 250 ml increments
5 | to 60 I by 1 | increments
Automatic dispense volume
Q-POD ® Accessory Dimensions
3% for volumes between
250 ml and 60 |
0
Volumetric dispense dispersion CV < 3% for volumes
Volumetric dispense accuracy Vel lan
579 mm (23.50 in)
230 mm (9.05 in)
Parameter
Q-POD® height
between 250 ml and 60 | O-POD® diameter
Dispenser delivery loop length 800 mm (31.49 in)
Q-POD® weight (packaged)
Q-POD® weight (empty)
7.2 kg (15.87 lb)
Type 3 Water Quality 5 kg (11.02 Ib)
Parameter
Value & Unit
97 to 98% with new RO
lons rejection
cartridge
Organics Rejection
> 99% for MW > 200 Dalton
> 99%
Particulates & Bacteria Rejection
Q-POD® weight (with water)
Loop & cable to system length
5.5 kg (12.12 Ib)
290 cm (114.1 in)
Data connection Parallel Port
(25-pinD-Sub)
for print-out
A report on conformity of Milli-O® Direct water quality with Type 1 water
quality as described by ASTM®, ISO® 3696 and CLSI® norms and to Purified
Water as described in USP and EP is available upon request.
ACCESSORIES
Customize your Milli-O® Direct system to meet your
specific needs.
Reservoirs
© Select from the range of EMD Millipore tanks from 30 | to 350
| designed for optimum pure water storage.
Q-POD® Dispenser: Ultrapure water delivery at your fingertips
e Save your bench space by removing the arm and dispenser
from the Milli-O® Direct system and mounting it on the
Q-POD® support.
Q-POD® dispenser key features:
e Variable water flow (slow flow to 2 l/min) controlled by
plunger.
e Volumetric water delivery controlled from the Q-POD® base.
e Designed to accommodate all sizes of glassware - 250 ml
cylinder, 5 | flask or even a 30 | carboy.
e Graphic display shows at a glance the water quality
specifications and all critical information you need (resistivity,
TOC level, alerts, alarms, etc.).
e Printer connection to instantly record water quality history.
For more information, please visit our website:
www.millipore.com/labwater
Wall Mounting Bracket
e Save space by installing the Milli-OQ® Direct on the wall or under
the bench.
Milli-OQ® Direct with Wall Mounting Bracket and
Q-POD®
Protectors:
e Water Sensor - placed on the floor, this sensor stops water feed
to the system if there is water on the floor.
e Tank Level Sensor - transfers tank level information to the
system to start & stop pure water production at levels selected
by the user. A safety level prevents air from entering the ultrapure
water part when the tank is empty.
e Silicone Cover to protect your Q-POD® from harsh chemicals,
such as strong acid & bases, aggressive solvents or etchants.
e UV lamp 254 nm: installed upstream from the inlet to the tank,
this optional UV lamp allows reduction of the level of bacteria in
the permeate water by a factor of 1000.
Footswitch
e Connect the footswitch to the base of the Q-POD® dispenser or
directly to the Milli-Q® system for hands-free water delivery: press
once to start and once to stop.
——
Millipore, Milli-Q, Progard, Jetpore, BioPak, EDS-Pak, Millipak, Q-POD, Q-Gard, Quantum, and Q-Pak are registered trademarks of Merck
KGaA, Darmstadt, Germany. VOC-Pak, LC-Pak, EMD Millipore and the M mark are trademarks of Merck KGaA. ASTM, ISO, and CLSI are
registered trademarks of their respective owners.
Lit. No. PB1032ENUS 01/12.
© 2012 EMD Millipore Corporation, Billerica, MA. All rights reserved.