Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
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ANNE E CRESS · UNIVERSITY OF FLORIDA · 2024 · $378,584 — ABSTRACT: The elevated ARDS mortality observed in the COVID-19 pandemic has highlighted the contribution of excessive mechanical stress produced by mechanical ventilation in promoting lethal increases in lung vascular permea- bility. Integrin β4 (ITGB4 gene) and kindlin-2 (FERMT2 gene) are essential…
Rafi Ahmed · EMORY UNIVERSITY · 2024 · $396,354 — ABSTRACT Immunological memory is a fundamental feature of the adaptive immune system. However emerging evidence demonstrates that the innate immune system can also display a form of adaptive, memory-like behavior, a phenomenon termed “trained immunity.” Recently using single cell ATAC-seq we demonst…
Cornelis Johan Elferink · BAYLOR COLLEGE OF MEDICINE · 2024 · $591,045 — SUMMARY: PILOT PROJECT PROGRAM The Pilot Project Program (PPP) is one of the key mechanisms by which the Gulf Coast-Center for Precision Environmental Health (GC-CPEH) enhances the environmental health identity and impact of the research base of its parent institutions, Baylor College of Medicine (B…
SANDRA WEINTRAUB · NORTHWESTERN UNIVERSITY AT CHICAGO · 2024 · $809,789 — PROJECT SUMMARY - CLINICAL CORE The Clinical Core will establish and maintain a cohort of extensively characterized individuals who have volunteered to participate in research projects addressing brain aging and dementia. In the next 5-year cycle, the Clinical Core of the Northwestern ADRC will cont…
Niteesh K Choudhry · BRIGHAM AND WOMEN'S HOSPITAL · 2024 · $339,500 — The Administrative Core represents the executive, coordinating, and oversight component of the Brigham and Women’s (BWH) Hospital Roybal Center for Therapeutic Optimization using Behavioral Science. The Core has a multi-disciplinary, multi-institutional governance and leadership organizational struc…
Melicia C Whitt-Glover · WASHINGTON UNIVERSITY · 2024 · $134,904 — PROJECT SUMMARY/ABSTRACT – Solutions to Diabetes in Black Americans National Resource Core The goal of the Solutions to Diabetes in Black Americans National Resource Core (SDBA) is to provide content, conceptual, and methodological expertise to improve the effectiveness and sustainability of transla…
Otakuye Conroy-Ben · INTER TRIBAL COUNCIL OF ARIZONA, INC. · 2024 · $119,201 — PROJECT SUMMARY Wastewater-based epidemiology (WBE) is a powerful tool that can measure population health in communities with centralized sewer treatment systems and is particularly relevant for Tribes who wish to assess health disparities such as COVID and substance abuse. In WBE, chemical metaboli…
Wilbur A Lam · EMORY UNIVERSITY · 2024 · $958,939 — Project Summary CORE 2: TECHNOLOGY CORE The mission of the NIH-funded Atlanta Center for Microsystems Engineered POC Technologies (ACME POCT) is to assist and enable inventors from across the country who have developed microsystems-based POC technologies in defining their specific clinical needs, re…
Susan Anne Tuddenham · JOHNS HOPKINS UNIVERSITY · 2024 · $191,515 — Dissemination Core Project Summary The long-term goal of the Johns Hopkins Center for Innovative Diagnostics for Infectious Diseases is to accelerate infectious disease diagnostic point-of-care (POC) technology innovation and access to impact global public health. The training of physical and comput…
Lin Yang · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · 2024 · $325,713 — Abstract – X-ray Scattering Technology Core The X-ray Scattering Technology Core will provide user access to the Life Science X-ray Scattering (LiX) beamline. During the current funding period we have refined the scientific focus of the LiX beamline, concentrating on supporting solution scatterin…
Claire M Kamp Dush · UNIVERSITY OF MINNESOTA · 2024 · $9,745 — DEVELOPMENT CORE: SUMMARY The goal of the Development Core is to mentor, retain, and develop the next generation of MPC leaders and to expand MPC research development services beyond the University of Minnesota. The Core has four aims: (1) Establish the MPC Population Scholars Program, an intensive …
Scott Dexter Boyd · STANFORD UNIVERSITY · 2024 · $187,844 — PROJECT 2: SUMMARY The B cell and plasma cell populations that give rise to serum and mucosal antibodies will ultimately determine the effectiveness and duration of an individual’s humoral immune response to SARS-CoV-2 infection. We will use several mutually-supporting strategies to analyze these ce…
Peter Connor · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $356,850 — PROJECT SUMMARY – ADMINISTRATIVE CORE Successful cancer centers, whether freestanding or matrix, master complexity, navigate dynamic external environments, and deliver cancer discovery to their community and patients. Effective administration provides infrastructure of quality services and partners …
Sarah A Nowak · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · 2024 · $208,911 — PROJECT SUMMARY: Sarah Nowak, PhD, Research Project Leader (RPL) The World Health Organization (WHO) has identified vaccine hesitancy as one of the top ten threats to global health. Vaccine hesitancy has been associated with beliefs that may be seemingly unrelated to vaccines, including both true…
Kira Grogg · YALE UNIVERSITY · 2024 · $31,490 — The overall goal of the CMITT Training program is to teach scientific advances made by biomedical researchers using PET/MR, while the main objective of our Dissemination program is to inform and educate the broader scientific community about the technical capabilities and accomplishments of simultan…
Padmini Salgame · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $1,687,027 — ABSTRACT Animal Models and Related Services (AMRS) Core The overall goal of Animal Models and Related Services (AMRS) Core 3 is to establish a biocontainment research support service core devoted to developing animal models of BSL3 pathogens and associated support services. Core 3 is highly relevant…
Sixto Manuel Leal · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $316,700 — Project Summary/Abstract: Core 3 outlines a strategic plan to establish integrated core services within the UAB SEBLAB enabling safe and efficient use of the cutting edge scientific equipment recently funded by NIAID award 1G20AI167409-S1. This proposal establishes six functional integrated research…
Bei Wu · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $679,009 — Research Project 3 – NYUCI-ES – Abstract The physical and emotional demands of dementia caregiving can have enormous negative effects on caregivers’ physical and mental health. Dementia caregivers have increased risk of hypertension and diabetes, compared to non-caregivers, especially in minority po…
ELIZABETH W KARLSON · BRIGHAM AND WOMEN'S HOSPITAL · 2024 · $339,909 — PROJECT SUMMARY/ABSTRACT – Resource Core 1: Human Biosamples Core Obtaining fresh, carefully phenotyped human samples is the most daunting logistical hurdle facing the Joint Biology Consortium (JBC) Research Community. The Human Biosamples Core overcomes this barrier with a “systems solution” that i…
PETER Thornton FOX · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2024 · $929,085 — The ISAVRAD U19 proposes a five-site, two-arm (patients and controls), longitudinal (3 assessments/subject) study enrolling 4,300 individuals. All 5 enrollment sites are experienced in recruiting genetically homogenous cohorts. Pilot data of various types are provided in the respective projects and …