Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
LYLE G BEST · MISSOURI BREAKS RESEARCH, INC. · 2024 · $120,454 — A. Summary of Funded Parent Grant: Factors Influencing Pediatric Asthma into Adulthood (R01MD019027) The prevalence of asthma among American Indian (AI) children is 9.3% as compared to 5.5% in non- Hispanic White children. Asthma disparities become even more pronounced into adulthood, with AI adults…
DANIEL T KAMEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $170,994 — PROJECT SUMMARY Leptomeningeal disease (LMD) is the metastasis of cancer cells into the pia arachnoid and cerebrospinal fluid (CSF), and is a devastating disease with survival rates of 4 months after diagnosis. Lumbar puncture (LP) with cytology is the gold standard for confirming the diagnosis of L…
Kelly Keisen Lee · UNIVERSITY OF WASHINGTON · 2024 · $589,522 — Protein-mediated membrane fusion is essential for a multitude of fundamental biological processes. Despite intensive study, at present we have a limited mechanistic understanding of how fusion protein machinery manipulates lipid membranes in order to induce their fusion. This lack of knowledge is pa…
CAMILA VENTURA · RESEARCH TRIANGLE INSTITUTE · 2024 · $612,740 — PROJECT SUMMARY/ABSTRACT Although rates of congenital Zika virus syndrome (CZS) have declined since the 2015–2016 Zika virus (ZIKV) outbreak in Brazil, transmission of the virus still occurs, with nearly 9,000 cases reported already in 2023. Without global eradication, the threat of another large ou…
Todd A Wyatt · OMAHA VA MEDICAL CENTER · 2024 — My primary research interests address chronic inflammatory lung disease, and the impact that behavioral and environmental exposures play in the compromise of lung innate defense against pathologic lung infections and injury. Utilizing pre-clinical mouse models and state-of-the-art molecular, biochem…
Thomas Kerr · UNIVERSITY OF BRITISH COLUMBIA · 2024 · $564,980 — PROJECT SUMMARY/ABSTRACT Overdoses deaths have increased sharply in Canada and the US since the outset of the COVID-19 pandemic. While fentanyl is a critical driver of North America’s overdose epidemic, rising fentanyl-stimulant polysubstance use and ongoing drug supply changes (fluctuating fentanyl…
Patricia L Hibberd · BOSTON UNIVERSITY MEDICAL CAMPUS · 2024 · $508,025 — Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS- CoV-2) was first reported in Wuhan, Hubei Province of China in December 2019 and by early 2021, there have been more than 100 million cases of COVID-19 globally. The consequences of COVID-19 in preg…
Gabriel Chamie · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $196,250 — Project Summary Dr. Gabriel Chamie is an infectious diseases physician and Associate Professor of Medicine in the Division of HIV, Infectious Diseases and Global Medicine at the University of California, San Francisco (UCSF). His research has focused on developing effective approaches to promote com…
Li-Tao Guo · RNACONNECT INC · 2024 · $1,555,946 — Summary RNA is the central biomolecule of life, as it connects the sequence of DNA to the production of proteins, and serves as a structural building block for critical components within the cell. Despite the importance of detecting, quantifying and sequencing RNAs in order to exploit their roles in…
Yong Chen · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $676,523 — SUMMARY Evidence-based medicine faces increasingly mounting challenges. With the explosively growing scientific literature, it will be harder than ever to identify the best evidence available, especially given the large volume of non-traditional and emerging sources of evidence: e.g., evidence deriv…
Syed Saif Hasan · UNIVERSITY OF MARYLAND BALTIMORE · 2024 · $411,570 — PROJECT SUMMARY The secretory pathway is responsible for the biogenesis of soluble and membrane proteins involved in communication, energy transduction, nutrient uptake, and defense. These proteins are synthesized in the endoplasmic reticulum (ER) and then trafficked to Golgi and other organelles su…
Carolina Vélez-Grau · BOSTON COLLEGE · 2024 · $196,992 — Over the past decade, youth reports of poor mental health, sadness, hopelessness, and suicide ideation have significantly increased. Suicide ideation is a risk factor for suicide attempts and death by suicide. Key risk factors include depression symptoms, low sense of belonging, and feeling like a b…
Dakota Danielle Witzel · SOUTH DAKOTA STATE UNIVERSITY · 2024 · $148,500 — Project Summary/Abstract Prolonged, elevated inflammation is detrimental to health, with ties to disease and mortality, making prolonged, elevated inflammation an economic burden and public health issue. Daily stressors and affective reactions to daily stressors may be mechanisms that increase risk …
Melanie Frances Molina · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $189,972 — PROJECT SUMMARY/ABSTRACT Dr. Melanie Molina is an Assistant Clinical Professor of Emergency Medicine at the University of California, San Francisco (UCSF) whose long-term goal is to become an independent investigator studying how to leverage health information technology to improve care for patient…
Erica DaVonne Farrand · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $189,332 — PROJECT SUMMARY Hybrid healthcare delivery is an integral part of the new healthcare landscape, connecting patients and clinicians using a combination of in-person and telehealth modalities. Hybrid models transform traditional chronic disease management, which is episodic, reactive, and expensive, t…
Lenore Pipes · UNIVERSITY OF CALIFORNIA BERKELEY · 2024 · $43,161 — Project Summary/Abstract The overall goal of this project is to use approaches from statistics and computer science to solve significant chal- lenges in the analysis of metabarcode and metagenomics data. Metagenomics, the study of combined genomes of organisms present in a single community, is an eme…
ELIZABETH J SANTA ANA · RALPH H JOHNSON VA MEDICAL CENTER · 2024 — Justification: High inpatient readmissions among Veterans with SUDs constitutes a costly and persistent healthcare problem. VHA Handbook 1160.06 guides the development and implementation of recovery-oriented mental health (MH) services, although significant service gaps remain on VA inpatient settin…
Connor J McCabe · UNIVERSITY OF WASHINGTON · 2024 · $249,000 — The long-term objective of this Pathway to Independence Award is to support candidate Dr. McCabe in building an independent research program and to facilitate his transition into an independent faculty research position. To date, Dr. McCabe’s research has focused on 1.) refining quantitative methods…
HERBERT M LACHMAN · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2024 · $252,000 — Program Director/Principal Investigator (Lachman, Herbert M) Abstract Mutations in PPM1D (Protein Phosphatase Magnesium-Dependent 1 Delta), which codes for a member of the protein serine-threonine phosphatase family, have recently been found in individuals with Jansen-De Vries Syndrome (JdVS), a con…
Benjamin L Karfunkle · VIRGINIA COMMONWEALTH UNIVERSITY · 2024 · $297,358 — The CORE-EM Hub Alliance (Coalition for Research in Emergency Medicine) was funded as a SIREN Hub in 2017 to facilitate excellence in resuscitation research. CORE-EM is currently ranked #2 for enrollments within SIREN, and is composed of six, highly experienced, multiple principal investigators (MPI…