Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Kevin Erickson · BAYLOR COLLEGE OF MEDICINE · 2024 · $537,879 — Approximately 750,000 adults in the United States (US) have end-stage kidney disease (ESKD), where they require either dialysis or a kidney transplant in order to survive. Although in-center hemodialysis (HD) is the most common treatment for ESKD, it is associated with extremely high costs and poor …
Jennifer Streiffer Mascaro · EMORY UNIVERSITY · 2024 · $150,229 — Project Summary/Abstract: Healthcare provider burnout is pervasive in oncology, and it imparts harm to providers and patients, increases healthcare and workforce disparities, and exacerbates projected physician and nursing shortages. Although burnout is primarily caused by organizational stressors, …
Edward W Boyer · OHIO STATE UNIVERSITY · 2024 · $191,325 — Abstract Renewal of my Midcareer Investigator Award in Patient-Oriented Research (K24) will allow me to continue my strong efforts directed toward successful original investigations and mentoring to generate research capacity in mobile technologies to improve health (mHealth). The impact of the init…
JESSICA R GOODKIND · UNIVERSITY OF NEW MEXICO · 2024 · $1,141,114 — PROJECT SUMMARY The goal of this study is to test a multilevel approach to reduce adverse consequences of the COVID-19 pandemic with disparate impacts on Latinx and Black immigrants and refugees by observing and implementing three nested levels of intervention: 1) an efficacious 6-month peer advocac…
Edwin Jose Asturias · UNIVERSITY OF COLORADO DENVER · 2024 · $596,565 — PROJECT SUMMARY Despite recent progress, accelerated implementation of highly effective and sustainable public health policies will be required to meet the Sustainable Development Goals’ (SDG) targets for maternal and child health by 2030. The broad goal of this application is to continue to partici…
Gianluca Ursini · LIEBER INSTITUTE, INC. · 2024 · $1,431,755 — PROJECT SUMMARY The extent to which SARS-CoV-2 infection in pregnancy affects the biology of the maternal-placental-fetal triad and neurodevelopmental trajectory in offspring is not known. Early studies indicate that SARS-CoV-2 can induce alterations in the placenta which can increase risk for adver…
Laura Su · UNIVERSITY OF PENNSYLVANIA · 2024 · $610,852 — Project Summary An ongoing outbreak of a novel coronavirus infection (COVID-19) has claimed millions of lives and disrupted social infrastructures around the world. Fortunately, the new mRNA vaccines from Moderna or Pfizer/BioNTech are highly effective against SARS-CoV-2. However, much remains unkno…
Christina Psaros · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $168,824 — PROJECT SUMMARY South Africa (SA) has the largest HIV epidemic in the world, with 7.2 million people infected and a prevalence of 18.8% among adults ages 15-49. Nurses constitute the largest group of providers in SA’s healthcare system and are frontline treaters in HIV care. They experience particul…
Anthony R Fehr · UNIVERSITY OF KANSAS LAWRENCE · 2024 · $359,480 — PROJECT SUMMARY ADP-ribosylation is an important post-translational modification that directly influences several biological processes including cancer, allergy, and infectious disease. ADP-ribose can be added to proteins as one or more consecutive units by ADP-ribosyltransferases, also termed PARP…
Stephen E Lankenau · DREXEL UNIVERSITY · 2024 · $1,164,507 — PROJECT SUMMARY/ABSTRACT Reducing overdose mortality immediately and long-term is a top public health priority as the overdose epidemic in the U.S. continues to worsen. The COVID-19 pandemic, which began hitting the U.S. in early 2020, has exacerbated the overdose crisis - particularly among African…
Wendy M Kohrt · UNIVERSITY OF COLORADO DENVER · 2024 · $1,100,000 — MoTrPAC Project Summary The Molecular Transducers of Physical Activity Consortium (MoTrPAC) will discover and characterize the range of potential molecular transducers that underlie the health benefits of exercise in humans. MoTrPAC was launched in 2016 with six adult Clinical Centers and a pediatri…
Jennifer Jo Connor · UNIVERSITY OF MINNESOTA · 2024 · $608,507 — ABSTRACT Female genital mutilation/cutting (FGM/C) affects girls and women throughout the world, with 3 million girls cut each year. The highest rates of FGM/C are in East Africa. There are significant reproductive, sexual, and mental health consequences for girls and women impacted by FGM/C. Health…
Saigopalakrishna Yerneni · MAYO CLINIC ROCHESTER · 2024 · $142,452 — Diffuse midline glioma (DMG) is a lethal pediatric brain tumor without a cure and with a poor prognosis. The H3K27M mutation is present in 80% of DMG patients and is the primary driver of the disease. Therefore, targeting this oncohistone using mRNA-based gene therapies may represent a promising tre…
Amy R Nelson · UNIVERSITY OF SOUTH ALABAMA · 2024 · $684,526 — PROJECT SUMMARY Postoperative pneumonia occurs in ~2-8% of patients following various surgeries and increases the length of hospital stay and mortality. Pneumonia is a common cause of sepsis. Some pneumonia survivors, including those with post-intensive care unit syndrome, suffer from cognitive defi…
Carmen Renee Green · CITY COLLEGE OF NEW YORK · 2024 · $3,939,001 — OVERALL-ABSTRACT The overall goal of the new RCMI at the City College of New York (CCNY) is to create an integrated multi-tiered center, the NYCenter for Minority Health, Equity, and Social Justice (NYC-MHESJ). This proposal is founded on the historic commitment of CUNY MED and CCNY to the Harlem co…
Michael V. Voronkov · SERODOPA THERAPEUTICS INC · 2024 · $1,539,426 — PROJECT SUMMARY There has been a dramatic rise in synthetic opioid-related deaths, primarily due to high-potency opioids such as fentanyl and its analogs. The cumulative burden of fatal and non-fatal fentanyl overdoses on public health is unprecedented. An effective overdose reversal agent to rapidl…
Lori Ann Orlando · DUKE UNIVERSITY · 2024 · $345,120 — This cost extension for the IGNITE network was requested by NHGRI program office in order to complete the activities for the network trials GUARDD and ADOPT-PGX as well as the follow-on network activities. The delays in the trials for GUARDD and ADOPT-PGX were multifactorial and were greatly influen…
James E. Gern · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $656,603 — Project Summary Proteomics analysis of URECA nasal secretions. Rationale. The URECA 14-17 year time point includes collection of nasal secretions by nasosorption to complement information that will be gained by analyzing nasal cell RNA and DNA. Analysis of nasal specimens collected at 11 year of age…
Ian David Aronson · NDRI-USA, INC. · 2024 · $461,653 — Project Summary/Abstract People who inject drugs (PWID) experience disproportionate risk of being infected with SARS-CoV-2, the virus that causes COVID-19. Unfortunately, due to stigma, fear of mistreatment, and other factors, PWID are far less likely to be vaccinated compared to other populations.…
HOWARD H GOLDMAN · UNIVERSITY OF MARYLAND BALTIMORE · 2024 · $766,659 — A major NIMH goal for early psychosis treatment is to “prevent deterioration and disability among individuals suffering from psychotic illness”. However, rates of Social Security Administration disability (SSI/DI) enrollment remain high for young people in early psychosis treatment. Existing studies…