Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Lindsay Fernandez-Rhodes · PENNSYLVANIA STATE UNIVERSITY, THE · 2024 · $160,400 — PROJECT SUMMARY One in four children in the United States (US) has at least one immigrant parent—more than a third of whom came to the US from Mexico more than any other country of origin. Children of Mexican immigrants, in particular those without documentation status, are exposed to psychosocial s…
Juliet Nabbuye Sekandi · UNIVERSITY OF GEORGIA · 2024 · $203,850 — PROJECT SUMMARY Poor adherence to oral medications is highly prevalent in 40-50% of patients with chronic diseases worldwide. Close monitoring of medication adherence is a critical part of successful routine patient care and drug efficacy trials but traditional observation methods of medication mon…
John Patrick Carey · JOHNS HOPKINS UNIVERSITY · 2024 · $768,514 — Project Summary Temporal bone research is essential for refining our understanding of the mechanisms of otologic disease; however, the difficulty in accessing this tissue, the typically long processing times, and the expense have contributed to a dwindling number of labs engaged in this work. In the…
SANDRA A BROWN · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2024 · $524,097 — PROJECT SUMMARY Excessive alcohol drinking Initiated during adolescence is known to disturb typical neurodevelopmental patterns, increase the risk of developing alcohol use disorder (AUD), and accelerate involutional processes in adulthood. In response to RFA-AA-21-008, the Administrative Resource (…
Dallas Hughes · NOVOBIOTIC PHARMACEUTICALS, LLC · 2024 · $992,480 — ABSTRACT The goal of this proposal is to investigate the potential for teixobactin (TXB) to treat drug-resistant tuberculosis (TB). TB is a major global health issue and second largest killer by an infectious agent. Non-compliance by TB patients due to lengthy treatment times have resulted in drug-r…
Mirella Dapretto · CEDARS-SINAI MEDICAL CENTER · 2024 · $1,802,205 — Neurodevelopmental processes are shaped by dynamic interactions between genes and environments. Maladaptive experiences early in life can alter developmental trajectories, leading to harmful and enduring developmental sequelae. Pre- and postnatal hazards include maternal substance exposure, toxicant…
Benjamin P. Linas · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $1,599,903 — The HEAL Data2Action (D2A) Program is a coordinated effort to promote the synthesis and real-world application of existing data to guide and monitor improvements in service delivery to prevent or treat opioid use disorder (OUD) and pain. Collectively, these projects will address gaps in the delivery…
STEPHEN B. KRITCHEVSKY · MAYO CLINIC ROCHESTER · 2024 · $744,685 — PROJECT SUMMARY/ABSTRACT Fundamental aging processes appear to be root-cause contributors to most of the disorders and diseases across the lifespan that account for the bulk of disability, mortality, and health costs. The goal of the nation-wide Translational Geroscience Network (TGN) is to accelera…
John S. Hutton · UT SOUTHWESTERN MEDICAL CENTER · 2024 · $149,693 — PROJECT SUMMARY Many children arrive at kindergarten unprepared to learn to read, at-risk of falling more behind, with major inequities linked to race, geography and poverty (rates >50%). These are amplified during disruptions such as COVID, when access to information and resources is perturbed. Low…
Patrick Dunn Smith · DREXEL UNIVERSITY · 2024 · $48,974 — Project Summary Each year, millions of US renters are legally evicted from their homes, with structurally marginalized groups – particularly Black and Latinx women – bearing the highest burden of evictions. Past research has shown that personal exposure to eviction worsens physical and mental health…
Haichao Wang · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · 2024 · $418,750 — PROJECT SUMMARY Microbial infections annually claim hundreds of thousands of victims in the U.S. alone, but its complex pathogenesis is still poorly understood. Our seminal discovery of HMGB1 as a late mediator of lethal endotoxemia (Science, 1999, Cited >4,000 times) has fueled continuous search fo…
James M Burke · UNIVERSITY OF FLORIDA · 2024 · $483,000 — PROJECT SUMMARY Ribonuclease L (RNase L) is a key component of the mammalian innate antiviral response. For decades, RNase L was presumed to reduce viral protein synthesis by cleaving ribosomes to arrest translation. However, we and others recently demonstrated that RNase L-cleaved ribosomes are tr…
MONICA L. BASKIN · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2024 · $1,492,336 — ABSTRACT The “Deep South,” including Alabama, Mississippi, and Louisiana, has the highest rates of obesity, diabetes and hypertension in the nation. As a result, life expectancy in the Deep South is substantially lower than other regions. The mission of the Deep South Center to Reduce Disparities in…
Renate Lux · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $236,250 — PROJECT SUMMARY Vaping of aerosolized tobacco and cannabis products using electronic nicotine delivery devices (ENDS) is increasingly popular among adolescents and young adults. The associated emerging health crisis has significant systemic and oral health implications as nicotine (N) consumption i…
Beth Phillips · OHIO STATE UNIVERSITY · 2024 · $684,388 — Reading difficulties continue to be a pervasive public health issue. Many children experience reading difficulties due to underdeveloped phonological awareness – and, specifically, phonemic awareness. Although decades of basic research have established phonemic awareness as causally related to readi…
Gregg Steven Gonsalves · YALE UNIVERSITY · 2024 · $719,401 — Project Summary There have been numerous outbreaks of human immunodeficiency virus (HIV) among people who use drugs (PWUD) since the well-publicized outbreak in Scott County, Indiana in 2015. In addition to HIV infections, hepatitis C virus (HCV) infections, skin and soft tissue infections (SSTI), s…
Ashly Elizabeth Jordan · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $227,861 — PROJECT SUMMARY/ABSTRACT Methadone treatment (MT) for opioid use disorder (OUD) significantly reduces overdose risk, but remains underutilized in the U.S. Limited availability of Opioid Treatment Programs (OTPs) – the only facilities licensed to dispense methadone, as well as regulations that have …
Maja J Mataric · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $299,999 — Untreated anxiety undermines long-term physical and emotional wellbeing, especially among college students, with rates worsening since the onset of the COVID-19 pandemic. Cognitive Behavioral Therapy (CBT) is the leading evidence-based intervention for anxiety, but many students fail to complete e…
Maria Mori Brooks · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $249,971 — PROJECT SUMMARY Telephone-based cognition testing lends itself more easily to a broader range of populations than in-person face-to-face testing, is cost-effective, and because it places a lower burden on study participants, reduces attrition in longitudinal studies. However, scores obtained from ph…
Rebeca Wong · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2024 · $1,694,384 — The Mexican Health and Aging Study (MHAS) is a longitudinal study using a national sample of community-dwelling adults aged 50 and older in urban and rural Mexico. Six waves of data collection over 20 years have been completed. Since its inception, the protocols and survey instruments are highly com…