Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
adrian u wiestner · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · 2024 · $1,371,922 — Monoclonal antibodies (mAbs) combined with chemotherapy improve survival of lymphoma patients. Fc receptor-dependent effector mechanisms achieve tumor cell killing but also induce antigen loss through trogocytosis. Activation of complement can lead to cell lysis and invariably deposits complement C3…
Tiffany Powell-Wiley · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · 2024 · $1,120,284 — We used epidemiologic data from the 1999-2002 National Health and Nutrition Examination Surveys to assess the relationship between neighborhood deprivation index (NDI) and log-transformed leukocyte telomere length (LTL) to begin to assess the biological mechanisms by which deprived neighborhood cond…
Narayana Manjunatha · HARVARD MEDICAL SCHOOL · 2024 · $817,815 — Project Summary Abstract Schizophrenia is a significant contributor to the global burden of disease. In India, this burden is further exacerbated because individuals living with schizophrenia have limited access to effective psychosocial interventions aimed at promoting recovery, rehabilitation, and…
Jessie Edwards · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $458,952 — PROJECT SUMMARY When an outbreak of an established or emerging infectious disease occurs we ask a standard set of questions that are critical to a lifesaving public health response: Where will future incidence occur? How many cases will there be? And where can we most effectively intervene? The prop…
C. Neill EPPERSON · UNIVERSITY OF COLORADO DENVER · 2024 · $203,926 — Abstract Physician-scientists serve a critical role in helping bridge the gap between basic and translational research and as noted in PAR-20-094 “bring a unique perspective to research through [a] blend of clinical and research experiences.” Thus training Psychiatrists for future careers as physici…
Jessica L. Adler · FLORIDA INTERNATIONAL UNIVERSITY · 2024 · $50,000 — PROJECT SUMMARY The disproportionate impact of covid-19 in U.S. jails and prisons offers stark evidence of a reality rooted in history: the incarceration of more than two million people constitutes a public health catastrophe. Mass incarceration threatens the well-being of communities and exacerbat…
Lona Mody · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $114,911 — ABSTRACT Frail older adults in institutional settings such as hospitals and nursing homes (NHs) are at a particularly high risk of poor outcomes. Translation of research findings into clinical practice, particularly in NHs, is challenging. Educating and training a multidisciplinary group of junior i…
Alfredo QUIJANO RUBIO · MONOD BIO, INC. · 2024 · $290,066 — Abstract. Bacterial endotoxins are components of the outer cell membranes of gram-negative organisms and is one of the most potent human toxins. Due to the health dangers associated with endotoxin contamination, testing is critical for pharmaceuticals, biological products, and medical devices. The m…
Briana Mezuk · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $216,643 — Summary The goal of this R25 proposal is to continue and expand our state-of-the-art, interdisciplinary training program to enhance the methodological skills of early-career scientists conducting integrative health research. Health and health inequities are a function of social, behavioral, biologic…
Jennifer Logan Green · SAN DIEGO STATE UNIVERSITY · 2024 · $151,672 — Project Summary/Abstract This K01 is a mixed methods research project in collaboration with an industry partner (i.e., Healthy Minds Innovations) and will be conducted across three aims during a 5-year comprehensive training program. In this innovative proposal, the candidate has identified a mentor…
ROBERT D HOWE · HARVARD UNIVERSITY · 2024 · $202,312 — Title Video Disease Activity Index: a video measure to monitor rheumatoid arthritis in telemedicine Project Summary/Abstract Rheumatoid arthritis (RA) is a degenerative autoimmune condition of the joints that is treated with medications that suppress the immune system. Medications must be regularly …
Katherine Segar · NEW YORK STRUCTURAL BIOLOGY CENTER · 2024 · $48,974 — PROJECT SUMMARY RNA viruses are an emerging health threat, evolving rapidly to proliferate and spread. Within these viruses are structured RNA elements that facilitate infection and virus survival. Internal Ribosome Entry Sites (IRESs) are a type of RNA structure found within RNA viruses that facili…
Mayumi Lynn Prins · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $16,251 — PROJECT SUMMARY/ABSTRACT Traumatic brain injury (TBI) is one of the top causes of death and disability worldwide. However, due to its complexity, it remains one of the most challenging neurological conditions to treat. Advances in our understanding of TBI pathobiology and improvements in clinical ca…
ANNE Marie MAURICIO · NORTHWEST PREVENTION SCIENCE INC · 2024 · $1,257,942 — Project Summary/Abstract Youth with mental health and behavior disorders have been underserved for decades, and many children receive no services at all. Since the COVID-19 pandemic, the need for effective mental health treatments for children and families has increased substantially, with research …
Umesh Ramanlal Desai · VIRGINIA COMMONWEALTH UNIVERSITY · 2024 · $489,038 — Anticoagulants are the mainstay in the treatment of thrombotic diseases, such as heart attack and stroke, and may also be used in other diseases such as cancer and COVID-19. Although several anticoagulants including heparins, warfarin, and direct oral anticoagulants (DOACs) are used in the clinic, e…
Adolfo Garcia-Sastre · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $785,873 — The objective of the Technology Core is to provide state-of-the-art, innovative -OMICs technologies for the targeted and global characterization of Project samples in a quantitative, reproducible, and efficient manner. The core brings together cutting-edge tools and the expertise of leading systems …
DOUGLAS A LAUFFENBURGER · SCRIPPS RESEARCH INSTITUTE, THE · 2024 · $501,406 — Project Summary - Modeling Core The Center for Viral Systems Biology (CViSB) collects and aggregates complex, multidimensional, and heterogeneous data, leading to challenges in interpreting these diverse experimental measurements. The Modeling Core’s primary goal is to develop and apply computationa…
Andrew Zelhof · TRUSTEES OF INDIANA UNIVERSITY · 2024 · $106,561 — Project Summary: The Drosophila Genomics Resource Center (DGRC) supports the international community of scientists utilizing Drosophila melanogaster for biomedical research. The mission of the DGRC is to 1) provide broad access to genomics resources by acquiring, authenticating, archiving, curating,…
SCOTT J. HULTGREN · WASHINGTON UNIVERSITY · 2024 · $366,301 — PROJECT SUMMARY/ABSTRACT: The climate surrounding COVID-19 has dramatically reminded us of the dire consequences of being unprepared for health crises. One looming health crisis is the surge of antibiotic-resistant bacterial infections that are no longer sensitive to our life saving antibiotic arsen…
Kari C. Nadeau · STANFORD UNIVERSITY · 2024 · $237,867 — 1 ABSTRACT – Clinical Core 2 The Clinical Core of the Stanford HIPC U19 will provide state-of-the-art clinical and biospecimen support for all 3 the research projects, the Immune Monitoring and the Data Management and Analysis Cores, as well as the 4 expertise, facilities, personnel, procedures a…