NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Sally Lynn Hodder · WEST VIRGINIA UNIVERSITY · 2024 · $960,949 — West Virginia (WV), the only state located entirely in Appalachia, has the lowest life expectancy in the nation and ranks at or near the bottom in many chronic disease categories. The WV Clinical and Translational Science Institute (WVCTSI) was created in 2012 through the initial Institutional Devel…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Alessandro Sette · LA JOLLA INSTITUTE FOR IMMUNOLOGY · 2024 · $2,391,540 — Project Summary – Overall The La Jolla HIPC team will focus on pathogens causing infectious diseases of the upper and lower respiratory tract that lead to substantial mortality and morbidity. Our approach is unique and innovative, as it focuses on defining immune signatures (IMS) of antigen-specifi…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
GABRIEL Alejandro DE ERAUSQUIN · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2024 · $8,610,822 — The science proposed in this program takes advantage of the unique scientific opportunity created by the ongoing coronavirus pandemic, to study the interaction between a definable and time-limited risk-inducing environmental event (exposure to the virus) and genomic variation on the occurrence of co…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Julie Parsonnet · STANFORD UNIVERSITY · 2024 · $193,000 — PROJECT SUMMARY At the start of the COVID-19 pandemic in late 2019, an estimated 1.2 million people—including 158,500 (13%) with undiagnosed infection—were living with HIV in the United States. Since then, HIV control efforts have been complicated by disruptions to HIV testing, care-related services…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
L Lee HAMM · TULANE UNIVERSITY OF LOUISIANA · 2024 · $9,304,973 — Project Summary – Overall The Tulane National Primate Research Center (TNPRC) is affiliated with Tulane University of Louisiana and was dedicated in 1964. The Center is part of Tulane University Health Sciences along with the School of Medicine, the School of Public Health and Tropical Medicine, and…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Mariano Juan Kanamori Nishimura · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2024 · $719,232 — PROJECT SUMMARY/ABSTRACT LatiNET will use a multilevel social network model to examine how SARS-CoV-2 misinformation and Conspiracy Theory (CT) messages are shared across five settings (friends, family, work, health service and influencers), impacting Latinx vaccine hesitancy. Social networks are se…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Christopher H Fox · AMERICAN ASSOCIATION FOR DENTAL, ORAL, AND CRANIOFACIAL RESEARCH · 2024 · $30,000 — Project Summary The American Association for Dental, Oral, and Craniofacial (AADOCR) Bloc Travel Grant program aims to target a diverse pipeline of the dental, oral, and craniofacial research workforce by providing travel and meeting support to the most promising U.S. dental and PhD students, reside…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
HENRY PAUL PARKMAN · TEMPLE UNIV OF THE COMMONWEALTH · 2024 · $378,877 — PROJECT SUMMARY Patients with gastroparesis often suffer with chronic symptoms that are not adequately treated due to both a lack of understanding of the underlying pathophysiology of gastroparesis and lack of effective treatments. Participation of Temple University as a clinical center in the NIDDK…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Sally Lynn Hodder · WEST VIRGINIA UNIVERSITY · 2024 · $3,997,470 — West Virginia (WV), the only state located entirely in Appalachia, has the lowest life expectancy in the nation and ranks at or near the bottom in many chronic disease categories. The WV Clinical and Translational Science Institute (WVCTSI) was created in 2012 through the initial Institutional Devel…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Sally Lynn Hodder · WEST VIRGINIA UNIVERSITY · 2024 · $299,858 — West Virginia (WV), the only state located entirely in Appalachia, has the lowest life expectancy in the nation and ranks at or near the bottom in many chronic disease categories. The WV Clinical and Translational Science Institute (WVCTSI) was created in 2012 through the initial Institutional Devel…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Jonathan B Overdevest · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $178,610 — PROJECT SUMMARY Smell loss is a common neurosensory disability accompanying infection with SARS-CoV-2 novel coronavirus. The frequency and persistence of alteration in the ability to smell, or olfactory dysfunction (OD), observed during the COVID-19 pandemic highlight a knowledge gap, where risk fac…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Bernadette Cortese · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2024 · $625,742 — ABSTRACT COVID exposed the critical need for new and improved treatment interventions for chemosensory (i.e. smell and taste) dysfunction. Evidence indicates that COVID-related smell loss (SL) often endures well past recovery of the initial infection and is highly associated with other long COVID ne…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Ryan P Bennett · OYAGEN, INC. · 2024 · $300,000 — The proposed Phase I SBIR will conduct IND-enabling studies to establish the pharmacokinetics (PK) and SARS-CoV-2 (CoV-2) antiviral efficacy of sangivamycin (Sang) in Golden Syrian hamsters. Sang is an adenosine nucleoside analog that we discovered to be a potent, dose- dependent inhibitor of CoV-2 …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Susan Moir · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2024 · $1,480,637 — In 2024, we pursued studies encompassing three major themes: 1) investigating B-cell function in lymphoid tissues of PLWH; 2) exploring the clinical benefits of HIV neutralizing antibodies; and 3) contributing to studies on B cells in non-HIV diseases. 1) In 2024, we began performing spatial transc…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
NICO TJANDRA · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · 2024 · $1,836,279 — As a progression in developing new technology to characterize dynamic molecular events which regulate important biological function, we chose to look at retroviral capsid assembly. This protein is a part of the Gag-poly protein which is processed as part of the maturation of the virus. The assembly …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Kathryn Saliba · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2024 · $19,598,023 — The Collaborative Clinical Research Branch (CCRB) is responsible for the Statement of Work of the CCRB Support Laboratories (Applied and Developmental Research Directorate, Leidos Biomedical Inc.), which are contracted through the National Cancer Institute-Frederick. The Laboratories support NIAID c…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Joshua Levy · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · 2024 · $1,415,699 — The goals of the Sinonasal and Olfaction program are to address unmet needs for improved patient care in smell, taste and inflammatory sinus disease. We lead mechanistic, translational and clinical studies that address one of two primary focus areas. 1) Sinonasal inflammation and its impact on olfac…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Jeffrey Reece · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · 2024 · $498,613 — The mission of the National Institutes of Health (NIH) is to seek fundamental knowledge about the nature and behavior of living systems and to apply that knowledge to enhance health, lengthen life, and reduce illness and disability. As part of the NIH, the National Institute of Diabetes and Diges…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
Gunjan Arora · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2024 · $625,921 — Viruses of the Coronaviridae family are enveloped viruses that possess a large (30kb), single-stranded, positive sense, RNA genome that infect a large number of mammals (alpha and beta coronaviruses) and birds (gamma coronaviruses). Four different seasonal coronaviruses (two alpha coronaviruses, 229…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2024
JERREL L YAKEL · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · 2024 · $2,741,932 — There have been several major accomplishments within the past fiscal year. This year we published 4 major papers, one of which promises to be one of the most significant discoveries yet from my lab (published in Cell Reports, and an NIEHS Intramural paper of the month), we have discovered a novel c…