Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Allison Leigh Speer · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · 2024 · $14,250 — Project Summary/Abstract In the past several decades, researchers have made extraordinary progress in our understanding of enteric nervous system (ENS) development and function. Vital scientific advances have occurred in identifying the major signaling pathways, transcription control, migratory beha…
MICHAEL J MORRIS · SLOAN-KETTERING INST CAN RESEARCH · 2024 · $1,177,039 — Project Summary/Abstract The MATCHES (Making Telehealth Delivery of Cancer Care at Home Effective and Safe) Telehealth Research Center aims to build the evidence base necessary to establish best practices for telehealth-enabled cancer care. The overarching goal of the Center is to create a research …
Andrew Otte · PURDUE UNIVERSITY · 2024 · $1,114,179 — Project Summary Buprenorphine has been proven as an important therapy in helping patients overcome opioid addition and in preventing overdose. Past usage of BUP has been shown to be both extremely safe and effective. Unfortunately, one of the major problems with all medication assisted treatment is …
Hadi Mohammadigoushki · FLORIDA STATE UNIVERSITY · 2024 · $189,456 — PROJECT SUMMARY/ABSTRACT Monoclonal antibodies (mAbs) represent an important class of biologic therapeutics that can treat COVID-19, cancer and other infectious diseases. Despite their promising potential, pro- cessing, storage and/or administration of mAbs into patients is challenging because the …
Milen Kirilov · INGENIOUS TARGETING LABORATORY, INC. · 2024 · $996,252 — Project Summary Genetically-modified mouse models have proven to be essential for the production of antibody-related biological drugs (biologics). To date, the majority of biologics originate from mouse models, and small animal models are used not only to generate the antibodies, but also as a platf…
Jason M Nagata · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $173,910 — PROJECT SUMMARY / ABSTRACT Cardiovascular disease (CVD) is the leading cause of death in the United States and physical activity is a potent way to decrease this risk. Serious gaps remain in our understanding of the optimal duration of physical activity and sedentary behavior during adolescence and …
Chulwoo Park · SAN JOSE STATE UNIVERSITY · 2024 · $183,125 — PROJECT SUMMARY Asian American immigrants have been particularly vulnerable to health disparities and mental health conditions during the COVID-19 pandemic in comparison to other racial/ethnic groups. There are multiple reasons: a language barrier, its impacts on isolation and marginalization, and a…
ANUPAM AGARWAL · BIRMINGHAM VA MEDICAL CENTER · 2024 — Project Summary Acute kidney injury (AKI) is a common and serious complication of medical and surgical diseases that has significant attributable morbidity and mortality in critically ill Veterans. Analysis of Veterans Health Administrative data reported that Veterans who develop AKI during a hospi…
Jenna Guthmiller · UNIVERSITY OF COLORADO DENVER · 2024 · $436,669 — PROJECT SUMMARY Influenza viruses remain a major global threat to human health, which is exacerbated by the lack of an effective vaccine. Humoral immunity does not target all parts of the virus evenly, a phenomenon known as immunodominance. Following seasonal vaccination, humans preferentially gener…
Nicola Decaro · OHIO STATE UNIVERSITY · 2024 · $239,852 — 1 Project Summary 2 There is growing evidence that canine coronaviruses (CCoVs) can infect humans and be associated with 3 clinical (mostly acute respiratory) illness in children and adults. Human infections with CCoVs with recombinant 4 canine-feline-porcine spike proteins (hCFPL-CoVs) have been…
Thomas Ekkehard Ritz · SOUTHERN METHODIST UNIVERSITY · 2024 · $485,483 — Summary Respiratory tract infections cause a considerable burden to health care systems and societies as a whole, which has been exasperated by COVID-19. Available preventative treatments for respiratory infections and the common cold have remained unsatisfactory and are often not adhered to. Psych…
CATHY H. WU · UNIVERSITY OF DELAWARE · 2024 · $433,379 — Protein Knowledge Networks and Semantic Computing for Disease Discovery The growing volume and breadth of information from the scientific literature and biomedical databases pose challenges to the research community to exploit the content for discovery. This MIRA grant application will advance our k…
CAROL L GALLETLY · MEDICAL COLLEGE OF WISCONSIN · 2024 · $541,052 — Over 44 million immigrants live in the US, and nearly half (44%) are Latinx. Historically, US immigrants have been reluctant to engage in public health infectious disease control measures such as testing, contact tracing, vaccination, and prompt medical care. Yet the public's cooperation is essentia…
H Hamdi Eryilmaz · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $463,290 — ABSTRACT Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a symptom-based diagnosis characterized by severe debilitating fatigue, cognitive dysfunction, and widespread pain. Most cases of ME/CFS begin with a viral infection or involve multiple exposures to pathogens over time. Soon aft…
JOEL H KRAMER · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $1,050,008 — PROJECT SUMMARY/ABSTRACT Small vessel cerebrovascular disease is common in the elderly, and is a well-known contributor to cognitive decline. A major gap in the field, however, is the ongoing need for reliable and reproducible biologic markers of vascular disease suitable for early detection, diseas…
Fudong Liu · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · 2024 · $769,918 — PROJECT SUMMARY To date over 16 million people in the US have been infected with the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19). While the vast majority will survive the acute illness, many are at risk for experiencing long-te…
Mary Allison Barlow · JOHNS HOPKINS UNIVERSITY · 2024 · $2,826,539 — PROJECT SUMMARY Drug and alcohol use related health problems and overdose deaths disproportionately impact quality and longevity of life for many American Indian and Alaska Native (Indigenous) communities. The proposed Community-Driven Indigenous Research, Cultural Strengths & Leadership to Advance …
Yuhua Bao · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $1,114,378 — Regulatory changes made in 2020 that relaxed criteria for take-home dosing (THD) of methadone offer an opportunity to improve retention in care with a lifesaving treatment. Methadone is a highly effective medication for treating opioid use disorders (OUD) that is provided in opioid treatment program…
Shannon M Monnat · SYRACUSE UNIVERSITY · 2024 · $417,609 — The COVID-19 pandemic and the mitigation policies it prompted may have had profound consequences for the psychological health of U.S. adults, including their risk of dying from drug overdose and suicide. To mitigate the spread of COVID-19, some U.S. states enacted policies like stay-at-home orders a…
Robert J. Gropler · WASHINGTON UNIVERSITY · 2024 · $1,310,650 — Overall Project Summary In this renewal application of our National Center for Biomedical Imaging and Bioengineering (NCBIB), the PET Radiotracer and Translation Center (PET-RTRC), our objective is to further fortify the Center as a national resource that leverages the expertise at Washington Univer…