Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
GABRIEL Alejandro DE ERAUSQUIN · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 2024 · $502,764 — P1 Abstract The novel coronavirus, SARS-CoV-2, spread worldwide, resulting in devastating consequences. Our preliminary data and several published studies strongly suggest that, in adults over 60 years of age, post- infectious cognitive impairment is present in nearly half of affected people, potent…
Monica Rosas Lemus · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2024 · $231,004 — SARS-CoV-2 caused the COVID-19 pandemic and millions of deaths worldwide. Although vaccines were developed in record time, the natural cycle of immunity is short and the rise of new variants complicates the development of herd immunity. New drugs have been proposed as antivirals however, it is known…
James M Holton · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · 2024 · $369,410 — Project Summary/Abstract - Core 3 – Flexible Macromolecular Crystallography This 3rd Technology Operations Core (TOC3) complements TOC1 by diversifying the ALS-ENABLE technology base to maximize flexibility in this now transformative era for structural biology. Artificial intelligence (AI) has revol…
GREGORY S MARTIN · EMORY UNIVERSITY · 2024 · $237,186 — The mission of the NIH-funded Atlanta Center for Microsystems Engineered POC Technologies (ACME POCT) has been assist and enable inventors from across the country who have developed microsystems-based POC technologies in defining their specific clinical needs, conducting clinical validation, and ref…
Matthew Hamill · JOHNS HOPKINS UNIVERSITY · 2024 · $500,514 — Clinical Core Project Summary The long-term goal of the Johns Hopkins Center for Innovative Diagnostics for Infectious Diseases (JH-C[ID]2) is to accelerate infectious disease diagnostic point-of-care (POC) technology innovation and access to impact global public health. Diagnostic advances in vitro…
ALEJANDRA CASILLAS · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $26,796 — Project Summary/Abstract - P50 Study #1 (BP REACH) Hypertension (HTN) is the leading contributor to preventable death, and a major risk factor for cardiovascular (CV) events. Suboptimal blood pressure (BP) control is the most common attributable CV risk factor, accounting for 56% of the burden of is…
Daniel Lingwood · HARVARD UNIVERSITY · 2024 · $411,028 — PROJECT SUMMARY/ABSTRACT: Advanced Lab Technologies Core One of the greatest added values of the HU CFAR has been facilitating member access to new and emerging technologies. Science is accelerated by changes in technology, and the evolution of flow cytometric, imaging and genomic techniques continu…
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2024 · $85,255 — This interagency agreement leverages the research capabilities, expertise, and interests of NIAID and the Veterans Health Administration (VHA) to respond to the current COVID-19 pandemic. Under this IAA, VHA research sites will participate in the ACTIV umbrella clinical research studies on candidat…
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2024 · $1,000,000 — To support the development of a non-human primate (NHP) lymph node (LN) microphysiologic system/tissue-on-a-chip with a focus on modeling immune responses to anti-viral vaccines (influenza, SARS-CoV-2) and testing the efficacy of these medical countermeasures.…
William Paul Duprex · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $587,096 — PROJECT SUMMARY/ABSTRACT The outbreak of COVID-19 has severely impacted global health and the economy. Cost-effective, highly efficacious therapeutics are urgently needed. Camelid VHH antibodies or nanobodies (Nbs) are small, highly stable, easily bioengineered, and can be rapidly and economically m…
Christina Gavegnano · VETERANS HEALTH ADMINISTRATION · 2024 — A major barrier to HIV eradication is maintenance of latently infected cells in people living with HIV (PWH). The Veteran population of PWH is nearly 2.5-fold greater versus non-Veteran individuals living in the United States, underscoring a major unmet need within the United States Veteran's popula…
Patricia Bamonti · VA BOSTON HEALTH CARE SYSTEM · 2024 — This study will develop and test the feasibility and limited-efficacy of a combined physical activity (PA) and cognitive-behavioral therapy intervention (bCBT) for Veterans with COPD, emotional distress (clinically significant depression and anxiety), and low PA level. Prior research has shown that …
ALEXANDER P REINER · UNIVERSITY OF WASHINGTON · 2024 · $761,033 — PROJECT SUMMARY The over-arching goal of this project is to address several major challenges to biologic interpretation, functional validation, and clinical translation of genetic association findings for quantitative red blood cell traits and non- malignant blood cell disorders in the post-genomic …
JONATHAN S MARCHANT · MEDICAL COLLEGE OF WISCONSIN · 2024 · $448,715 — PROJECT SUMMARY Increases in cellular Ca2+ resulting from activation of intracellular Ca2+ channels regulate many physiological events. Dysfunction of intracellular Ca2+ signaling pathways is involved in many disease states. To appreciate how cell functions are controlled by Ca2+ signals, and how pa…
LISA A MAIER · NATIONAL JEWISH HEALTH · 2024 · $646,640 — PROJECT SUMMARY/ABSTRACT: The goal of this study is to define cell-specific regulatory networks and key drivers of cellular response to beryllium (Be) that result in the granulomatous lung disease, chronic beryllium disease (CBD), at the site of organ involvement. Relying on the complementary, uniqu…
Patricia Elizabeth Prusaczyk · WASHINGTON UNIVERSITY · 2024 · $116,371 — 1 This is an application for a K01 award for Beth Prusaczyk, PhD, MSW, whose research focuses 2 on improving the health of vulnerable older adults, such as those with Alzheimer’s disease and 3 related dementias (ADRD) living in rural areas, by improving systems of care. The experiences 4 of those…
CARYN LERMAN · UNIVERSITY OF SOUTHERN CALIFORNIA · 2024 · $6,579,621 — PROJECT SUMMARY – Overall Component The USC Norris Comprehensive Cancer Center at the University of Southern California (NCCC) has been continuously funded as an NCI-designated Comprehensive Cancer Center since 1973. NCCC has a rich tradition of collaborative research and serves as a major regional …
susmita chowdhuri · JOHN D DINGELL VA MEDICAL CENTER · 2024 — Patients recovering from acute COVID-19 infection often suffer from a multitude of debilitating chronic physical symptoms that can last up to 6 months or more. The incidence of fatigue, cognitive impairment and respiratory symptoms are reported to be very high in the post-COVID period. The underlyin…
Dan Winer · BUCK INSTITUTE FOR RESEARCH ON AGING · 2024 · $543,472 — PROJECT SUMMARY / ABSTRACT Obesity is a major global health concern. When people become obese, the body fails to respond well to insulin, called insulin resistance. This process can lead to high blood sugar triggering type 2 diabetes, though the underlying causes are poorly understood. We have shown…
SYLVIA J. HYSONG · MICHAEL E DEBAKEY VA MEDICAL CENTER · 2024 — BACKGROUND. Screening lies at the heart of preventive care. However, COVID-19 has dramatically disrupted routine screening efforts, resulting in excess veteran mortality not directly attributable to COVID-19. Screening rates at VA during COVID have varied markedly by facility and clinical condition.…